DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nub and acj6

DIOPT Version :9

Sequence 1:	NP_001097153.1	Gene:	nub / 34669	FlyBaseID:	FBgn0085424	Length:	961	Species:	Drosophila melanogaster
Sequence 2:	NP_524876.1	Gene:	acj6 / 47080	FlyBaseID:	FBgn0000028	Length:	396	Species:	Drosophila melanogaster

Alignment Length:	410	Identity:	140/410 - (34%)
Similarity:	193/410 - (47%)	Gaps:	76/410 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   575 PGMSSP----QAQLAAAGLGMNNPLLTGSLSPQDFAQFHQLLQQRQVALTQQFNSYMELLRSGSL 635
            ||..||    ..|:...   |.||.:..|.|......  :||:...:..    ||: ...::|.:
  Fly    21 PGRYSPSYRSSEQMRRC---MPNPSIHISSSCDSLES--RLLEDASLLC----NSW-SARQNGDI 75

  Fly   636 GLAQDDPALT-AQVAAAQFLMQSQLQAL-SQASQQLQ--------ALQKQQQRQVDE-PL--QLN 687
            ....:|..|: |:..||..:.:.|.|.: ||...|::        ::....||.:.| |.  |::
  Fly    76 FAGINDGILSRAEALAAVDIQKHQAQHVHSQMPSQIKHDVMYHHHSMSGPPQRPLQENPFSRQMH 140

  Fly   688 HKMTQQPRSSTPHSIRSPIAIRSPASSPQQLHHH-----------HHHPLQITPPSSAASLKLSG 741
            |.|.|........|:.:...|.....:|...|.|           ||||               |
  Fly   141 HSMDQLDMLDPTGSMTTLAPISESPLTPTHQHLHGSYHSMNHMMSHHHP---------------G 190

  Fly   742 MLTPSTPTSGTQMSQGTTTPQPKTVASAAAARAAGEPSPEETTDLEELEQFAKTFKQRRIKLGFT 806
            .|  |..|.|.........|    |.:||.| ||| ..|:..||..|||.||:.|||||||||.|
  Fly   191 TL--SGHTGGHHGHSAVHHP----VITAAVA-AAG-LHPDTDTDPRELEAFAERFKQRRIKLGVT 247

  Fly   807 QGDVGLAMG--KLYG-NDFSQTTISRFEALNLSFKNMCKLKPLLQKWLDDADRTIQATGGVFDPA 868
            |.|||.|:.  ||.| ...||:||.|||:|.||..||..|||:||.||::|:  .||.....||.
  Fly   248 QADVGKALANLKLPGVGALSQSTICRFESLTLSHNNMIALKPILQAWLEEAE--AQAKNKRRDPD 310

  Fly   869 ALQATVSTPEII--GRRRKKRTSIETTIRGALEKAFLANQKPTSEEITQLADRLSMEKEVVRVWF 931
            |       |.::  |.:::|||||....:.:||..|....:|:.|:|..:|::|.::|.||||||
  Fly   311 A-------PSVLPAGEKKRKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAEKLDLKKNVVRVWF 368

  Fly   932 CNRRQKEKRINPSL-DSPTG 950
            ||:|||:|||..|: .|.||
  Fly   369 CNQRQKQKRIVSSVTPSMTG 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nub	NP_001097153.1	DUF4472	315..>399	CDD:291409
		POU	791..855	CDD:197673	39/66 (59%)
		Homeobox	886..939	CDD:278475	25/52 (48%)
acj6	NP_524876.1	POU	222..299	CDD:197673	44/76 (58%)
acj6	NP_524876.1	Homeobox	323..377	CDD:395001	25/53 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464261
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3802
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840