DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nub and pou1f1

DIOPT Version :9

Sequence 1:	NP_001097153.1	Gene:	nub / 34669	FlyBaseID:	FBgn0085424	Length:	961	Species:	Drosophila melanogaster
Sequence 2:	NP_998016.1	Gene:	pou1f1 / 405777	ZFINID:	ZDB-GENE-040630-7	Length:	350	Species:	Danio rerio

Alignment Length:	347	Identity:	118/347 - (34%)
Similarity:	170/347 - (48%)	Gaps:	96/347 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   683 PLQLNHKMTQQPRSSTPHSIRSPIAIRSPASSPQQLHHHH-------------HHPL-------- 726
            ||.::|.......::   :|.|.:....|.....:..|.|             |:|:
Zfish    24 PLLMHHSAAADCHNT---NICSTVPSGLPLVQSSKRSHMHLSTSALGNASASLHYPMPPCHYSNQ 85

  Fly   727 QITPPSSAASLKLSGML-------TPSTP----TSGTQMSQGTTTPQ----PK-TVASAAAARAA 775
            |.|....||...||..:       |.|.|    .:|....||...|:    |: ::|..:.|.:.
Zfish    86 QTTYGMMAAQEMLSASISQTRILQTCSVPHANMVNGANSLQGALAPRLYKFPEHSLAGGSCALSH 150

  Fly   776 G-EPSP------------------------EETTDLE-----ELEQFAKTFKQRRIKLGFTQGDV 810
            | .|.|                        :||.|::     |||:||..||.||||||:||.:|
Zfish   151 GFAPLPQTLLTDEPILGDIKQELRRKSRTLDETPDMDSPQIRELEKFANDFKLRRIKLGYTQTNV 215

  Fly   811 GLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLDDADRTIQATGGVFDPAALQATVS 875
            |.|:..::|::||||||.|||.|.|||||.||||.:|.|||::|::    .|.:|:
Zfish   216 GEALAAVHGSEFSQTTICRFENLQLSFKNACKLKSILAKWLEEAEQ----AGALFN--------- 267

  Fly   876 TPEIIG---RRRKKRTSIETTIRGALEKAFLANQKPTSEEITQLADRLSMEKEVVRVWFCNRRQK 937
              |.:|   |:||:||:|....:.|||::|:...||:|:||.::|:.|.:||||||||||||||:
Zfish   268 --EKMGLHERKRKRRTTISLGAKEALERSFVEKSKPSSQEIVRMAEGLHLEKEVVRVWFCNRRQR 330

  Fly   938 EKRINPSLDSPTGADDDESSYM 959
            |||:..||        ..||:|
Zfish   331 EKRVKTSL--------HHSSFM 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nub	NP_001097153.1	DUF4472	315..>399	CDD:291409
		POU	791..855	CDD:197673	39/63 (62%)
		Homeobox	886..939	CDD:278475	28/52 (54%)
pou1f1	NP_998016.1	POU	186..260	CDD:197673	42/73 (58%)
pou1f1	NP_998016.1	Homeobox	279..332	CDD:278475	28/52 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810