DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment nub and Pou5f1

DIOPT Version :9

Sequence 1:	NP_001097153.1	Gene:	nub / 34669	FlyBaseID:	FBgn0085424	Length:	961	Species:	Drosophila melanogaster
Sequence 2:	NP_001009178.1	Gene:	Pou5f1 / 294562	RGDID:	1359491	Length:	352	Species:	Rattus norvegicus

Alignment Length:	219	Identity:	99/219 - (45%)
Similarity:	131/219 - (59%)	Gaps:	19/219 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   726 LQITPPSSAASLKLSGMLTPSTPTSGTQMSQGTTTPQPKTVASAAAARAAGEPSPEETTDL---- 786
            |.:.|.....:|:..|.......::....|.|..|.:|..|.....     ||||||:.|:
  Rat    77 LGLVPQVGVETLQPEGQAGARVESNSEGASSGPCTARPSAVKLEKV-----EPSPEESQDMKALQ 136

  Fly   787 EELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWL 851
            :|||||||..||:||.||:||.||||.:|.|:|..||||||.|||||.||.||||||:|||:||:
  Rat   137 KELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSLKNMCKLRPLLEKWV 201

  Fly   852 DDADRTIQATGGVFDPAALQATVSTPEIIGRRRKKRTSIETTIRGALEKAFLANQKPTSEEITQL 916
            ::||..          ..||....:..::..|::||||||..:|..||..||...||:.::||.:
  Rat   202 EEADNN----------ENLQEICKSETLVQARKRKRTSIENRVRWNLENMFLQCPKPSLQQITSI 256

  Fly   917 ADRLSMEKEVVRVWFCNRRQKEKR 940
            |.:|.:|::||||||||||||.||
  Rat   257 AKQLGLERDVVRVWFCNRRQKGKR 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nub	NP_001097153.1	DUF4472	315..>399	CDD:291409
		POU	791..855	CDD:197673	43/63 (68%)
		Homeobox	886..939	CDD:278475	30/52 (58%)
Pou5f1	NP_001009178.1	POU	131..205	CDD:197673	47/73 (64%)
Pou5f1	NP_001009178.1	Homeobox	226..280	CDD:395001	30/53 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810