Protein Alignment nub and Pou5f1

DIOPT Version :10

• Sequence 1: NP_001097153.1
• Gene: nub / 34669
• FlyBaseID: FBgn0085424
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_038661.2
• Gene: Pou5f1 / 18999
• MGIID: 101893
• Length: 352
• Species: Mus musculus
• Alignment Length: 222
• Identity: 100/222 - (45%)
• Similarity: 138/222 - (62%)
• Gaps: 25/222 - (11%)

  Fly   726 LQITPPSSAASLKLSGMLTPSTPTSGTQM---SQGTTTPQPKTVASAAAARAAGEPSPEETTDL- 786
            |.:.|.....:|:..|.       :|.::   |:||:: :|......|......||:|||:.|:
Mouse    77 LGLVPQVGVETLQPEGQ-------AGARVESNSEGTSS-EPCADRPNAVKLEKVEPTPEESQDMK 133

  Fly   787 ---EELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQ 848
               :|||||||..||:||.||:||.||||.:|.|:|..||||||.|||||.||.||||||:|||:
Mouse   134 ALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSLKNMCKLRPLLE 198

  Fly   849 KWLDDADRTIQATGGVFDPAALQATVSTPEIIGRRRKKRTSIETTIRGALEKAFLANQKPTSEEI 913
            ||:::||..          ..||....:..::..|::||||||..:|.:||..||...||:.::|
Mouse   199 KWVEEADNN----------ENLQEICKSETLVQARKRKRTSIENRVRWSLETMFLKCPKPSLQQI 253

  Fly   914 TQLADRLSMEKEVVRVWFCNRRQKEKR 940
            |.:|::|.:||:||||||||||||.||
Mouse   254 THIANQLGLEKDVVRVWFCNRRQKGKR 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nub	NP_001097153.1	POU	791..855	CDD:197673	43/63 (68%)
		Homeodomain	884..940	CDD:459649	31/55 (56%)
Pou5f1	NP_038661.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48
		9aaTAD. /evidence=ECO:0000250|UniProtKB:Q01860	4..12
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..115		6/31 (19%)
		POU	131..205	CDD:197673	47/73 (64%)
		DNA-binding. /evidence=ECO:0000269|PubMed:23376973, ECO:0007744|PDB:3L1P	173..179		5/5 (100%)
		DNA-binding. /evidence=ECO:0000269|PubMed:23376973, ECO:0007744|PDB:3L1P	186..189		1/2 (50%)
		Homeodomain	224..280	CDD:459649	31/55 (56%)