DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nub and Pou1f1

DIOPT Version :9

Sequence 1:	NP_001097153.1	Gene:	nub / 34669	FlyBaseID:	FBgn0085424	Length:	961	Species:	Drosophila melanogaster
Sequence 2:	NP_032875.1	Gene:	Pou1f1 / 18736	MGIID:	97588	Length:	291	Species:	Mus musculus

Alignment Length:	281	Identity:	109/281 - (38%)
Similarity:	155/281 - (55%)	Gaps:	56/281 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   706 IAIRSPASSPQQLHHHHHHPLQITPPSSAASLKLSGM--LTPSTPTS--GTQMS-----QGTTTP 761
            |.:.|.||:...| ..||...:..|.|:.|:..:|..  |..|.|:.  |.|.|     .|:.||
Mouse    13 ITLNSDASAALPL-RMHHSAAECLPASNHATNVMSTATGLHYSVPSCHYGNQPSTYGVMAGSLTP 76

  Fly   762 ------------------QPKTVASAAA----------ARAAGEPSPEETTDLEELEQFAKTFKQ 798
                              ||......||          ::...||...::.::.||||||..||.
Mouse    77 CLYKFPDHTLSHGFPPLHQPLLAEDPAASEFKQELRRKSKLVEEPIDMDSPEIRELEQFANEFKV 141

  Fly   799 RRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLDDADRTIQATGG 863
            ||||||:||.:||.|:..::|::||||||.|||.|.|||||.||||.:|.|||::|::    .|.
Mouse   142 RRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQ----VGA 202

  Fly   864 VFDPAALQATVSTPEIIG---RRRKKRTSIETTIRGALEKAFLANQKPTSEEITQLADRLSMEKE 925
            :::           |.:|   |:||:||:|....:.|||:.|..:.||:|:||.::|:.|::|||
Mouse   203 LYN-----------EKVGANERKRKRRTTISVAAKDALERHFGEHSKPSSQEIMRMAEELNLEKE 256

  Fly   926 VVRVWFCNRRQKEKRINPSLD 946
            |||||||||||:|||:..||:
Mouse   257 VVRVWFCNRRQREKRVKTSLN 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nub	NP_001097153.1	DUF4472	315..>399	CDD:291409
		POU	791..855	CDD:197673	40/63 (63%)
		Homeobox	886..939	CDD:278475	28/52 (54%)
Pou1f1	NP_032875.1	POU	124..198	CDD:197673	43/73 (59%)
Pou1f1	NP_032875.1	Homeobox	217..270	CDD:278475	28/52 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910