DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ref2 and alyref

DIOPT Version :9

Sequence 1:	NP_001246007.1	Gene:	Ref2 / 34667	FlyBaseID:	FBgn0032439	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_001017027.1	Gene:	alyref / 549781	XenbaseID:	XB-GENE-973553	Length:	260	Species:	Xenopus tropicalis

Alignment Length:	210	Identity:	65/210 - (30%)
Similarity:	95/210 - (45%)	Gaps:	38/210 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSDKMKMSLDDIIKMKFNKNKFVNAK--NERVQGGSIRKRNSEGGLRGIQRSRNGTG-------- 55
            |.|||.||||||||:..::......:  ....:|||  .|...||..|..|...|.|
Frog     1 MGDKMDMSLDDIIKLNRSQRPAGRGRGGGRGARGGS--ARGGAGGRIGGGRGGGGGGAAGGGGPM 63

  Fly    56 -----FIRKSKFKQETLLKPPKKPT---------------------LVMVCNLDYGVDDDDIMEL 94
                 ..|..:.:.....:|.:.|.                     .::|.|||:||.|.||.||
Frog    64 RSRPVLTRGGRNRPAPYSRPKQLPDKWQHDLFDSGFGTGAGMETGGKLLVSNLDFGVSDADIQEL 128

  Fly    95 FNQDGVVEKGFVHYDRDGNSLGTAHLSFKYREEAFQIIEQFHGVRLDGRRLKLHLVQNTRNFKRT 159
            |.:.|.::|..|||||.|.|||||.:.|:.:.:|.:.::|::||.||||.:.:.||.:....:|.
Frog   129 FAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIEAQRR 193

  Fly   160 DVDDLSLRMGSFKTR 174
            .:...|...|..:.|
Frog   194 PIQSQSRGGGITRPR 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ref2	NP_001246007.1	RRM	2..>198	CDD:223796	64/209 (31%)
Ref2	NP_001246007.1	RRM_SF	75..149	CDD:302621	34/94 (36%)
alyref	NP_001017027.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..89		25/89 (28%)
		RRM_THOC4	109..183	CDD:241124	34/73 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	189..260		4/20 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1369069at2759
OrthoFinder	1	1.000	-	-		FOG0001223
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19965
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020