DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ref2 and Poldip3

DIOPT Version :9

Sequence 1:	NP_001246007.1	Gene:	Ref2 / 34667	FlyBaseID:	FBgn0032439	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_001123978.1	Gene:	Poldip3 / 315170	RGDID:	1311073	Length:	420	Species:	Rattus norvegicus

Alignment Length:	156	Identity:	38/156 - (24%)
Similarity:	70/156 - (44%)	Gaps:	31/156 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KMSLDDIIKM-KFNKNKFVNAKNERVQGGSIRKRNSEGGLRGIQRSRNGTGFIRKSKFKQETLLK 69
            |:|:...:.: |..:|   :|....|...|:|.:    .|..:.|:     .:.|.:..:|.
  Rat   218 KLSMSKTLPLTKVVQN---DAYTAPVLPSSVRTK----ALTNMSRT-----LVNKEELPKEL--- 267

  Fly    70 PPKKPTL-------VMVCNLDYGVDDDDIMELFNQDGVVEKG-FVHYDRDGNSLGTAHLSFKYRE 126
            ||.:|.|       :.|.||...|.::||:|||...|.:::. .||       .|.|.:.|..::
  Rat   268 PPAEPVLSPLEGTKMTVNNLHPRVTEEDIVELFCVCGALKRARLVH-------PGVAEVVFVKKD 325

  Fly   127 EAFQIIEQFHGVRLDGRRLKLHLVQN 152
            :|....::::...|||:.:|.:|..|
  Rat   326 DAITAYKKYNNRCLDGQPMKCNLHMN 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ref2	NP_001246007.1	RRM	2..>198	CDD:223796	38/156 (24%)
Ref2	NP_001246007.1	RRM_SF	75..149	CDD:302621	21/81 (26%)
Poldip3	NP_001123978.1	RRM	216..406	CDD:223796	38/156 (24%)
Poldip3	NP_001123978.1	RRM_SKAR	280..348	CDD:241125	20/74 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0533
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19965
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910