Protein Alignment Ref2 and Ncl

DIOPT Version :10

• Sequence 1: NP_609574.1
• Gene: Ref2 / 34667
• FlyBaseID: FBgn0032439
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_036881.2
• Gene: Ncl / 25135
• RGDID: 3153
• Length: 714
• Species: Rattus norvegicus
• Alignment Length: 230
• Identity: 58/230 - (25%)
• Similarity: 99/230 - (43%)
• Gaps: 51/230 - (22%)

  Fly    18 NKNKFVN----------AKNE----RVQGGSIRK------RNSEGGLRGIQRSRNGTGFIRKSKF 62
            |.||.|.          |||:    .|:.|:.||      .::|    .::::...||.   ..|
  Rat   320 NPNKSVAELKVAISELFAKNDLAAVDVRTGTNRKFGYVDFESAE----DLEKALELTGL---KVF 377

  Fly    63 KQETLLKPPK--------KPTLVMVCNLDYGVDDDDIMELFNQDGVVEKGFVHYDRDGNSLGTAH 119
            ..|..|:.||        ....::..||.:.:.:|::.|:|  :..||...|  .:||.|.|.|:
  Rat   378 GNEIKLEKPKGRDSKKVRAARTLLAKNLSFNITEDELKEVF--EDAVEIRLV--SQDGRSKGIAY 438

  Fly   120 LSFKYREEAFQIIEQFHGVRLDGRRLKLHLV-QNTRNFKRTDVDDLSLRMGSFKTRFLQNGTFKT 183
            :.||...:|.:.:|:..|..:|||.:.|:.. :..:..:||..:  |...|..||..|.|.::..
  Rat   439 IEFKSEADAEKNLEEKQGAEIDGRSVSLYYTGEKGQRQERTGKN--STWSGESKTLVLSNLSYSA 501

  Fly   184 --RSLQNGFQKSRLFRNSSFKPRPFKKHNFKSRAF 216
              .:||..|:|      ::|...|...|. ||:.:
  Rat   502 TEETLQEVFEK------ATFIKVPQNPHG-KSKGY 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ref2	NP_609574.1	RRM_SF	75..149	CDD:473069	22/73 (30%)
Ncl	NP_036881.2	8 X 8 AA tandem repeats of X-T-P-X-K-K-X-X	58..135
		RRM1_NCL	312..386	CDD:409837	17/72 (24%)
		RRM2_NCL	395..470	CDD:409838	22/78 (28%)
		RRM3_NCL	489..561	CDD:409839	13/48 (27%)
		RRM4_NCL	576..653	CDD:409840
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	646..714