Protein Alignment bun and tsc22d1

DIOPT Version :9

• Sequence 1: NP_001036357.2
• Gene: bun / 34665
• FlyBaseID: FBgn0259176
• Length: 1331
• Species: Drosophila melanogaster
• Sequence 2: NP_001315054.1
• Gene: tsc22d1 / 335842
• ZFINID: ZDB-GENE-030131-7785
• Length: 971
• Species: Danio rerio
• Alignment Length: 1311
• Identity: 298/1311 - (22%)
• Similarity: 425/1311 - (32%)
• Gaps: 482/1311 - (36%)

  Fly    19 PGNNPVRRNSMLTPSRGVTIGGTGGNIRKLTKVS-SLTSNH-HFAVCYPPSNIYQNSNNAGSNSA 81
            |.:.|.|.||..|         .||:....|..| ||.||: ..|..|.|..:.|:.....|:..
Zfish    51 PMSLPRRENSSST---------VGGSSTLTTSASTSLNSNNLMLADEYSPPVLIQSQTQTASSLG 106

  Fly    82 LQRTTSESLRLNMMSRVAAGATPTTVSRASSNSSLATSTSTSLAPKSSSSSGGSNSTPQQQQQQL 146
            .| ....||.:.:.:.:.....||.|::....|....   ||:.|..:|.|..::.|...:....
Zfish   107 PQ-NPPHSLSIPLQTPMLPQTLPTAVAQMKKKSGFQI---TSVTPAQTSVSTNNSITEDTESCDD 167

  Fly   147 VSSNNSSSSSNNSFTKASSPNNNGARSVGGAATSAATGT--------TAAAGSHHHQP------- 196
            :..:::...|::.....|.|..|.:   ||...|::..|        |..|.|.:..|
Zfish   168 LDESHTEDLSSSEIMDVSLPRANNS---GGPERSSSEETLNNFHEAETPGALSPNQPPIITQAHL 229

  Fly   197 H--------HHHHHHHHHHQHHNHQQQQQQQTSLSQGHASLTVAGGSASAGGGGGGG-------- 245
            |        ||||||||||.|||                  .|:.|.....||...|
Zfish   230 HGTMVNGTVHHHHHHHHHHHHHN------------------PVSSGKTHPAGGTLIGVPLGAPVT 276

  Fly   246 SGSSSGTAAGGTNRKPKTTSSFEITSV----TVGHPKLNAAGDTG---DESADDLDESHTDDNSR 303
            |..:|.:|:.|...........|..||    .:|.|....|..||   ..|...:...:|..|:.
Zfish   277 SVVTSSSASTGQKMPSNVVGLIENASVGTTSAIGQPLATLASGTGVISVTSGATISTGNTLTNNV 341

  Fly   304 ITDLENETPSMSEDTFSKEEVYYAN--NALSTNAPVIPTSSQYGLVVVDPIAPSLGQTIQNVQVN 366
            ........|.:...|.:...|.|::  |::|...|.: |....|::       .:|.|   ....
Zfish   342 SVLNSASVPVVGGKTTNSSSVNYSSALNSISNQTPNL-THVPSGII-------GMGIT---AAAT 395

  Fly   367 VSDNIINVVSGAVTP----------------GGTKKKDDIKETQHRSERFKVVKIEST-EPFKRG 414
            ||.::.:...|.:.|                ....::..:......|.||:|||::|| ||||:|
Zfish   396 VSGSVASTGGGQMGPAVMGQHAMPAPSVPVMSAQPQQAQVPTPASTSSRFRVVKLDSTSEPFKKG 460

  Fly   415 RWMCMDYLDHSSVGNGGNNNEKTGSSTSEAHAATTDGGAAGVGAGSEAPAHKTTQSMILPPTQKL 479
            ||.|.:|.|..                           |..|.:...||:.:|.:|:
Zfish   461 RWTCTEYYDKE---------------------------APNVASSENAPSTRTVESI-------- 490

  Fly   480 NENHLEANSTDANWNYAEQQQQQQQQQQQQQTIVGNALTKTLPVALRNVSRSSSVTRSPNATVE- 543
                             .|...:....|.:.|:.|::::.:  .:....|..|..|..|:...:
Zfish   491 -----------------RQCVPESVAGQDRDTVSGSSVSSS--ASHYTESLGSGETGGPSTVKQT 536

  Fly   544 FLSPNLLAQQQQQQQQLFDSVNANAASSPNPAGDPNNMDYARTAAMQLHQTLQQLKQREDAMDVP 608
            |..|    ..|.|.|.|........|::|.||          ||.:|     ||          |
Zfish   537 FQQP----MSQMQPQDLVQVHLKTNAAAPMPA----------TANIQ-----QQ----------P 572

  Fly   609 PGA-GGYANYQNGGDSAVGAASNNNSAAAATGESQLSTSYVEQQQQQQQPLSPAPLTPQAAPTFA 672
            |.: ||                             |.|:.|:         |.||| |...|...
Zfish   573 PASIGG-----------------------------LQTTIVQ---------SSAPL-PSHMPKLT 598

  Fly   673 AVAAGQSPNFQ----LEQQQ------QQQQATSQIDGIVPQPFNPQQQQQQTPQQ-STAQQAAAA 726
            ...|.|||..|    :.|||      ||..|.:|   :.|...||..|....|.. |.::|..:
Zfish   599 YAQAAQSPPAQALPVVTQQQMGYPPAQQPAAPAQ---VAPTHVNPLSQGGSLPSDFSQSKQILS- 659

  Fly   727 ANATSAVTAPPPQQTSNTSNAAVTTGQGQTMPLLSHMTSYEQQQPNLGAAAAAAAAGGTAATSVA 791
                   |.||              |..:|:|.||           ......|.|..|...|..:
Zfish   660 -------TVPP--------------GSTKTLPHLS-----------ASIPPVALAGNGQMITPSS 692

  Fly   792 APQAIPTLQLQSAPSTIADPQQLMVPQQQQQQQHQEEQQQQPQQQQQPLPPANIASASANNSNLN 856
            .|   ||  .|..|..:..|||...||.         .|..||..|
Zfish   693 QP---PT--AQPLPQGLLQPQQTPAPQM---------VQVVPQLVQ------------------- 724

  Fly   857 LTNTNVVATGEATTNALTLTDEQATAALAAAFATGAAAAATGATSAAAATQQQIQQLQQQPNAES 921
                                                   :||.|   ...|...|||..||:.|.
Zfish   725 ---------------------------------------STGTT---LIQQTPGQQLTSQPSMEQ 747

  Fly   922 ETESFITASNPGGNRKRAFSNPHIGGPNDPSFMHRLNPQ--LYYYNKSQSGRSSFCVDESLWPTN 984
            :.:|.:.:...|.....|.::..: .||..|     :||  |:.....::|
Zfish   748 QQQSQLGSQARGTQFVPAVTSSSV-PPNIQS-----DPQSSLFQNGSKETG-------------- 792

  Fly   985 NPNGAVSDTNLYMGSSTDEDYEEAIDQFSPTIYTTRSASRAIPIPNSAGSSPQHQMHHSQPRIAI 1049
             |..|||                           ||.:  .:|:.::.....|||...:|.:.|
Zfish   793 -PQPAVS---------------------------TRPS--VMPLEDAQLLLLQHQALLAQTKPA- 826

  Fly  1050 GINQMEGGGPTRSTGAFSASPSIYAYPHSPFYASSPETSFGSAAMPGHPAASSRISFSYDPAFQR 1114
                  ||.....||.                :..||.|.|..|:
Zfish   827 ------GGESASQTGT----------------SRGPEGSSGVNAL-------------------- 849

  Fly  1115 LQVPNASGDRRPRSPLECASVFAAVAAAATCGDAAGGAADTVISSASGTSAVAIDNKIEQAMDLV 1179
                :||.......|::              |:..|         :||.|.||||||||||||||
Zfish   850 ----SASASLLKSLPVD--------------GEEDG---------SSGASVVAIDNKIEQAMDLV 887

  Fly  1180 KSHLMIAVREEVEVLKERISELMDKINKLELENSILKSNIPQETLQQLQLQLQL----------A 1234
            |||||.|||||||||||:|.||:::.::||.||::||:....|.|.|.|.|:|.          |
Zfish   888 KSHLMYAVREEVEVLKEQIKELLERNSQLEQENNLLKNLASPEQLAQFQAQVQSGSSPPSSAQGA 952

  Fly  1235 APPATPAIQAA 1245
            ..|.||:.|.|
Zfish   953 QQPPTPSAQLA 963

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bun	NP_001036357.2	TSC22	1176..1223	CDD:279505	29/46 (63%)
tsc22d1	NP_001315054.1	TSC22	884..940	CDD:279505	34/55 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589769
Domainoid	1	1.000	68	1.000	Domainoid score	I9683
eggNOG	1	0.900	-	-		E1_KOG4797
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001302
OrthoInspector	1	1.000	-	-		otm25341
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2903
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.770