Protein Alignment Oatp33Eb and Slco6d1

DIOPT Version :9

• Sequence 1: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: XP_011246380.1
• Gene: Slco6d1 / 70866
• MGIID: 1918116
• Length: 729
• Species: Mus musculus
• Alignment Length: 645
• Identity: 132/645 - (20%)
• Similarity: 242/645 - (37%)
• Gaps: 119/645 - (18%)

  Fly    31 GLGWCRGPGCQKYARLRTFI----LVLAISGTLQGACESYFRVSAKQASFQFGWNPLIVDWLLVA 91
            |||....|..|::..:::|:    |.:.....:....:...::...|.|     ...|.::|:..
Mouse    68 GLGSLVFPCLQRFNNVKSFLTLSFLAVVAHSMIFALVDQSIKLYVAQLS-----PSRIEEYLMDT 127

  Fly    92 SGLFQA-VFALAFAYWADVYHPIKWLVGTLMLQAVTCVVAVIPSIMNFADGNQAKDALLDANMCA 155
            |..|.| :|::..|::....:...|:.....|..:..:|..:| .:||        .::..::..
Mouse   128 SDNFVAFLFSMFVAHFGGRGNRANWVAAGCFLTGIAAIVFAVP-FLNF--------EIIKLSVVK 183

  Fly   156 TSLAQFQRLTL----TEAQSSSLTLAMLFVLQLALGMGGLAYYTLGVSYIDDNSLSQDSPAVIGA 216
            ..|.:..:|..    |.....|:.:.:....|...|:.||..|.|..|:|.|:..:..|...|..
Mouse   184 EELCEEGKLPKVCEPTVLPHKSICIFIFIFGQCLHGIAGLPLYILATSFIFDHVPTNSSGLYIAL 248

  Fly   217 ALAARVFG------------QQAGSFLVLGVG------LTHVGWWLGWVILAPFIFVGAV-LLGL 262
            ..||...|            :.:...::..||      :...|||..::.:|.|.|...: |||
Mouse   249 VDAALGVGYCLGFIGGMLNFKMSAQEVMQAVGHRQRIRILQRGWWRTFIFVAVFAFCTTLPLLG- 312

  Fly   263 FPKRLP-----------------------------KTVIHQAAQRIIEQSSMRRFGSQFSTYMD- 297
            ||..||                             |:|:|  |..|..:..:.......||.:.
Mouse   313 FPSSLPGARQIRLEKSQEPPTFDRRLKNKEIKNNLKSVLH--ATWIYHRGHLTILSQTCSTSLGG 375

  Fly   298 ----------DSDFWPSLKRLFNNRLLMFNLLSIMCVQSAVVNY---GLQEESYLQSRFFLPYNE 349
                      |.|.....:.|..|.|:   |..::|..:....:   .:....|||:||.:
Mouse   376 ICCSTTGKAIDGDLQKLTQCLIRNPLV---LSQVVCKFTEFTTFKSSAVFLPQYLQTRFLI---- 433

  Fly   350 QDGLAAEWRSAFVSYFLKPPVMALGMLISGLVISKAKLSARKITGINIALSIHLVAIFIGLIFVQ 414
            :...|:.....|:.     |....|....|.::.:.:::.:......:..|...:.:|:...||:
Mouse   434 RPSSASMLTGVFIL-----PGSIFGHFFGGFIVHRMQMNNKNKLKFLVVASFVSIVLFLLTFFVE 493

  Fly   415 CDVGAIAGVEG--------GKLKQPYCSSQCLCTPTAFMPVCPENSSVTYFSPCYAGCTKKTTIN 471
            |::...||:..        |.|..| |:..|.||.:.:.|||..:.: .|||||:|||.....:.
Mouse   494 CEISKFAGINDDYDRLGIIGNLTAP-CNVPCGCTTSEYNPVCGRDET-QYFSPCFAGCKATKKLR 556

  Fly   472 SFQLFEGCSC--SGDQSLNSTGQ-MRATAGACSSDNCQSAIIIFQIMSISVAFLMGVGAIGKTLI 533
            ..:.:..|||  .|..:.::.|| :.|.:|.|:: .|.:..:.|... .:..||....:|...||
Mouse   557 KEKTYYNCSCIKEGLTTADNEGQYIDAVSGTCNT-RCLTLPLFFAFY-FTATFLSSFCSIPSALI 619

  Fly   534 TLRAVLPQDKSLALAFELMIVGLFAYVPVHLSYDIVTRTTCVYWAPN----YERCLLRET 589
            .:::|.....|::|.....:......||..:.:...:..||.:|..|    ..||.:..|
Mouse   620 VIQSVPTSWNSMSLGLMSTVWRFTGSVPAPILFAATSDFTCQFWGINECGEKVRCWIYNT 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Eb	NP_609570.1	oat	23..619	CDD:273279	132/645 (20%)
		MFS	50..>267	CDD:119392	47/244 (19%)
		KAZAL_SLC21	430..483	CDD:238650	19/54 (35%)
Slco6d1	XP_011246380.1	MFS	83..622	CDD:391944	115/571 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810