Protein Alignment Oatp33Eb and SLCO1A2

DIOPT Version :9

• Sequence 1: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_001373807.1
• Gene: SLCO1A2 / 6579
• HGNCID: 10956
• Length: 670
• Species: Homo sapiens
• Alignment Length: 595
• Identity: 142/595 - (23%)
• Similarity: 254/595 - (42%)
• Gaps: 94/595 - (15%)

  Fly    44 ARLRTFILVLA---ISGTLQGACESYFRVSAKQASFQFGWNPLIVDWLLVASGLFQ---AVFALA 102
            ::|:.|:|.:.   :|.||.|   ||......|...||.....:|.::   :|.|:   .:..:.
Human    17 SKLKMFLLAITCAFVSKTLSG---SYMNSMLTQIERQFNIPTSLVGFI---NGSFEIGNLLLIIF 75

  Fly   103 FAYWADVYH-PIKWLVGTLMLQAVTCVVAVIPS-IMN--------FADGNQAKDALLDANMCATS 157
            .:|:....| ||...:|.::: .:.|.:..:|. :||        ...||.:.::.|    |..:
Human    76 VSYFGTKLHRPIMIGIGCVVM-GLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFL----CMEN 135

  Fly   158 LAQFQRLTL--TEAQSSSLTLAMLFVL--QLALGMGGLAYYTLGVSYIDDNSLSQDSPAVIGAAL 218
            ..|..|.|.  :|......:|..::||  .:..|||......||:|||:|.:..::||..||...
Human   136 GTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVE 200

  Fly   219 AARVFGQQAGSFLV-------LGVGLTH-------------VG-WWLGWVILAPFIFVGAVLLGL 262
            ...:.|...|..|.       :..|..:             || ||.|::|.|....:.|:....
Human   201 TGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFF 265

  Fly   263 FPKRLPKTVIHQAAQRI-IEQSSMRRFGSQFSTYMDDSDFWPSLKRLFNNRL-LMFNLLSIMCVQ 325
            .|..|||..:...|..| .|....::...:...|....||.|.:|.|..|.: ::|.|:|:
Human   266 LPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYGITKDFLPFMKSLSCNPIYMLFILVSV---- 326

  Fly   326 SAVVNYGLQEESYLQSRFFLP-YNEQD-GLAAEWRSAFVSYFLKPPVMALGMLISGLVISKAKLS 388
                   :|..:::....|:| |.||. |:::......:..:..||: .:|.:|.||::.|.|::
Human   327 -------IQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPI-CIGYIIGGLIMKKFKIT 383

  Fly   389 ARKITGINIALSIHLVAIFIGLIFVQCDVGAIAGV----EGGKLKQPY---------CSSQCLCT 440
            .::...|...||:....::.....:.|:..::.|:    ||  :.|..         |:..|.|.
Human   384 VKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEG--IPQDLYVENDIFADCNVDCNCP 446

  Fly   441 PTAFMPVCPENSSVTYFSPCYAGCTKK--TTINSFQLFEGCSCSGDQSLNSTGQMRATAGAC-SS 502
            ...:.||| .|:.::|.|.|.|||...  |.||  .:|:.|||     :.::|...|..|.| ..
Human   447 SKIWDPVC-GNNGLSYLSACLAGCETSIGTGIN--MVFQNCSC-----IQTSGNSSAVLGLCDKG 503

  Fly   503 DNCQSAIIIFQIMSISVAFLMGVGAIGKTLITLRAVLPQDKSLALAFELMIVGLFAYVPVHLSYD 567
            .:|...:..|.|:|...:|:..:.||...::.||.:..::|||.:........:||.:|..:.:.
Human   504 PDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFG 568

  Fly   568 IVTRTTCVYW 577
            .:..:||::|
Human   569 ALMDSTCLHW 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Eb	NP_609570.1	oat	23..619	CDD:273279	142/595 (24%)
		MFS	50..>267	CDD:119392	59/257 (23%)
		KAZAL_SLC21	430..483	CDD:238650	21/63 (33%)
SLCO1A2	NP_001373807.1	oat	1..625	CDD:273279	142/595 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810