Protein Alignment Oatp33Eb and SLCO2A1

DIOPT Version :9

• Sequence 1: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_005621.2
• Gene: SLCO2A1 / 6578
• HGNCID: 10955
• Length: 643
• Species: Homo sapiens
• Alignment Length: 611
• Identity: 141/611 - (23%)
• Similarity: 245/611 - (40%)
• Gaps: 115/611 - (18%)

  Fly    36 RGPGCQK--YARLRTFILVLAISGTLQGACESYFRVSAKQASFQFGWNPLIVDWLLVASGLFQAV 98
            |...|.:  :..::.|:|...:....|....:||:.|......:||.:......:...:.:..|:
Human    19 RAGRCARSVFGNIKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAI 83

  Fly    99 FALAFAYWAD-VYHPIKWLVGTLMLQAVTCVVAVIPSIMN-------FADGNQAKDALLDANMCA 155
            ..:..:|:.. |:.|....:|.|.| |....:..:|..::       .:.||.::   |.|.:|.
Human    84 LIIFVSYFGSRVHRPRLIGIGGLFL-AAGAFILTLPHFLSEPYQYTLASTGNNSR---LQAELCQ 144

  Fly   156 TSLAQFQRL--------TLTEAQSSSLTLAMLFVLQLALGMGGLAYYTLGVSYIDDNSLSQDSPA 212
               ..:|.|        |....:.:|....::.|.||..|:|.:.....|:||:||.|...:||.
Human   145 ---KHWQDLPPSKCHSTTQNPQKETSSMWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEPSNSPL 206

  Fly   213 VIGAALAARVFGQQAGSFLVLGVGLTHV-----------------------GWWLGWVILAPFIF 254
            .|....|..|||...|  .:||..:..:                       .||||.:|.:..:.
Human   207 YISILFAISVFGPAFG--YLLGSVMLQIFVDYGRVNTAAVNLVPGDPRWIGAWWLGLLISSALLV 269

  Fly   255 VGAVLLGLFP-------KRLPKTVIHQAAQRIIEQSS-------MRRFGSQFSTYMDDSDFWPSL 305
            :.:.....||       ||.|.|.  ..|:::.|..|       ::||...|
Human   270 LTSFPFFFFPRAMPIGAKRAPATA--DEARKLEEAKSRGSLVDFIKRFPCIF------------- 319

  Fly   306 KRLFNNRLLMFNLLSIMCVQSAVVNYGLQEESYLQSRFFLPYNEQDGLAAEWRSAFVSYFLKPPV 370
            .||..|.|.:..:|: .|..|:|: .||   |...::|.   .:|.|.:|.:.: |:...:..|.
Human   320 LRLLMNSLFVLVVLA-QCTFSSVI-AGL---STFLNKFL---EKQYGTSAAYAN-FLIGAVNLPA 375

  Fly   371 MALGMLISGLVISKAKLSARKITGINIALSIHLVAIFIGLIFVQCDVGAIAGVEGGKL------K 429
            .|||||..|:::.:...|.:.|..|...:....:.:.:.|.|:.|....:|.|.....      :
Human   376 AALGMLFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMGCSTPTVAEVYPPSTSSSIHPQ 440

  Fly   430 QPYCSSQCLCTPTAFMPVCPENSSVTYFSPCYAGCT--KKTTINSFQL-FEGCSCSGDQSLNSTG 491
            .|.|...|.|..:.|.|||.:| .:.|.|||:|||:  ..::..|.|| :..|||.      :.|
Human   441 SPACRRDCSCPDSIFHPVCGDN-GIEYLSPCHAGCSNINMSSATSKQLIYLNCSCV------TGG 498

  Fly   492 QMRATAGACSSDNCQSAII--IFQIMSISVAFLMGVGAIGKT---LITLRAVLPQDKSLALAFEL 551
            ...|..|:|... |...::  ||.|..:|:     :..|...   ::.||.|..::||.|:..:.
Human   499 SASAKTGSCPVP-CAHFLLPAIFLISFVSL-----IACISHNPLYMMVLRVVNQEEKSFAIGVQF 557

  Fly   552 MIVGLFAYVPVHLSYDIVTRTTCVYW 577
            :::.|.|::|....|.:....:|:.|
Human   558 LLMRLLAWLPSPALYGLTIDHSCIRW 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Eb	NP_609570.1	oat	23..619	CDD:273279	141/611 (23%)
		MFS	50..>267	CDD:119392	54/262 (21%)
		KAZAL_SLC21	430..483	CDD:238650	22/55 (40%)
SLCO2A1	NP_005621.2	oat	1..630	CDD:273279	141/611 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145475
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740