Protein Alignment Oatp33Eb and Slco1c1

DIOPT Version :9

• Sequence 1: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_067446.1
• Gene: Slco1c1 / 58807
• MGIID: 1889679
• Length: 715
• Species: Mus musculus
• Alignment Length: 670
• Identity: 156/670 - (23%)
• Similarity: 277/670 - (41%)
• Gaps: 126/670 - (18%)

  Fly    38 PGCQKYARLRTFILVLAISGTLQGACESYFRVSAKQASFQFGWNPLIVDWLLVASGLFQ----AV 98
            |.|.|   |:.|:..|:.....:...|.|.:.:..|...:|.....:|.   :..|.|:    .|
Mouse    37 PCCGK---LKVFLGALSFVYFAKALAEGYLKSTVTQIERRFEIPSSLVG---IIDGSFEIGNLLV 95

  Fly    99 FALAFAYWADVYHPIKWLVGTLMLQAVTCVVAVIPSIM---------NFADGNQAKDALLDANMC 154
            ......:.|.::.|.....|.|::...|.::||....|         .::..:....::....:.
Mouse    96 ITFVSYFGAKLHRPKIIGAGCLVMGFGTMLIAVPQFFMEKYSYEKYERYSPSSNVTPSISPCYLE 160

  Fly   155 ATS------LAQFQRLTLTE--AQSSSLTLAMLFVLQLALGMGGLAYYTLGVSYIDDNSLSQDSP 211
            ::|      |.:.|.....|  ..|||.....:|:..|..|:|......||::|:||.:...::.
Mouse   161 SSSPSPSSILGKSQNKISHECVGDSSSSMWVYVFLGNLLRGLGETPIQPLGIAYLDDFASEDNAA 225

  Fly   212 AVIG----AALAARVFGQQAGS-----FLVLG-VGLTHV-----------GWWLGWVILAPFIFV 255
            ..||    .|:...:||...||     ::.:| |.|.|:           .||||::|......:
Mouse   226 FYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGFLSLL 290

  Fly   256 GAVLLGLFPKRLPKTVIHQAAQRIIEQSSMRRFG--SQFSTYMDD-------------------S 299
            .||.....||.||::            .|....|  |:.|.::||                   .
Mouse   291 AAVPFWCLPKTLPRS------------QSRENSGSTSEKSKFIDDPIHYQMAPGDDKMKIMEMAK 343

  Fly   300 DFWPSLKRLFNNRLLMFNLLSIMCVQSAVVN--YGL--QEESYLQSRFFLPYNEQDGLAAEWRSA 360
            ||.||||.||.|.:.:..|    |..:...|  :|:  .:..|::        :|.|.::. ::.
Mouse   344 DFLPSLKTLFRNPVYILYL----CASTVQFNSLFGMVTYKPKYIE--------QQYGQSSS-KAN 395

  Fly   361 FVSYFLKPPVMALGMLISGLVISKAKLSARKITGINIALSIHLVAIFIGLIFVQCDVGAIAGV-- 423
            ||...:..|.:|||:...|:|:.|.:|...:.|.:.:..|:....:|:.|..:.|:..::||:
Mouse   396 FVIGLINIPAVALGIFSGGIVMKKFRLGICEATKLYLGSSVFGYLLFLSLFALGCENSSVAGLTV 460

  Fly   424 --EGGKLKQPY-------CSSQCLCTPTAFMPVCPENSSVTYFSPCYAGCTKKTTINSFQLFEGC 479
              :|.|....:       |:|:|.|:.:.:.|:|.:| .:||.|.|.|||...:......:|..|
Mouse   461 SYQGTKPVSYHERALFSDCNSRCKCSDSKWEPMCGDN-GITYVSACLAGCQSSSRSGKNIIFSNC 524

  Fly   480 SCSG---DQSLNSTGQMRATAGACSSDN-CQSAIIIFQIMSISVAFLMGVGAIGKTLITLRAVLP 540
            :|.|   .:|.|.:|.|    |.|..|| |....:.|.::|:..::.:.:|.|...::.||.:.|
Mouse   525 TCVGFAAPKSGNWSGMM----GRCQKDNGCSQMFLYFLVISVITSYTLSLGGIPGYILLLRCIQP 585

  Fly   541 QDKSLALAFELMIVGLFAYVPVHLSYDIVTRTTCVYWAPNYER------CLLRETPKHGNILDIL 599
            |.||.||....:.|.:.|.:|..:.:.::..|:|:.|  .:::      |.|.::....:|...|
Mouse   586 QLKSFALGIYTLAVRVLAGIPAPVYFGVLIDTSCLKW--GFKKCGSRGSCRLYDSHAFRHIYLGL 648

  Fly   600 TASLILASVLFDILVYIFAK 619
            |..|...||...:.|....|
Mouse   649 TTLLGTVSVFLSMAVLFVLK 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Eb	NP_609570.1	oat	23..619	CDD:273279	155/668 (23%)
		MFS	50..>267	CDD:119392	53/258 (21%)
		KAZAL_SLC21	430..483	CDD:238650	17/59 (29%)
Slco1c1	NP_067446.1	OATP	44..641	CDD:281175	144/631 (23%)
		MFS	46..>302	CDD:119392	53/258 (21%)
		KAZAL_SLC21	475..528	CDD:238650	17/53 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810