Protein Alignment Oatp33Eb and slco1c1

DIOPT Version :9

• Sequence 1: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: XP_005164528.1
• Gene: slco1c1 / 562772
• ZFINID: ZDB-GENE-041210-50
• Length: 710
• Species: Danio rerio
• Alignment Length: 641
• Identity: 149/641 - (23%)
• Similarity: 271/641 - (42%)
• Gaps: 132/641 - (20%)

  Fly    19 NIPDDSVDCGIKGLGWCRGPGCQKYARLRTFILVLAISGTLQGACESYFRVSAKQASFQFGWNPL 83
            |.|..|..|            |..:   :.|::.|:.:...:....||.:.:..|...:|.
Zfish    34 NSPSSSRRC------------CSSF---KMFLVALSFAYFSKALSGSYMKSTITQLERRFD---- 79

  Fly    84 IVDWLL-VASGLFQ----AVFALAFAYWADVYHPIKWLVGTLMLQAVTCVVAVIPSIMNFADGNQ 143
            |..:|: |..|.|:    .|.|....:.|.::.|....:|.|::...|.::|    :.:|..|..
Zfish    80 IPSYLIGVIDGSFEIGNLLVIAFVSYFGAKLHRPKIIAIGCLLMSLGTFLIA----LPHFIIGRY 140

  Fly   144 AKDALLDANMCATSLAQFQRLTLTEAQSSSL---------TLAM---LFVLQLALGMGGLAYYTL 196
            ..:..:..::.::|......|:..|..:||:         .|:|   :|:..:..|:|......|
Zfish   141 KFETSIRLSVNSSSSLSPCSLSSAEPSTSSVPSTGCEHESRLSMWIYVFLGNILRGIGETPVQPL 205

  Fly   197 GVSYIDDNSLSQDSPAVIGA----ALAARVFGQQAGSF---LVLGVGLTHV-------------- 240
            |:|||||::|.:::...||.    ::...|||...||.   :.:.:|..::
Zfish   206 GISYIDDHALEENAAFYIGCVQTISVIGPVFGYLLGSVCAKIYVDIGFVNMESISITPGDARWVG 270

  Fly   241 GWWLGWVILAPFIFVGAVLLGLFPKRLPKTVIHQAAQRIIEQSSMRRFGSQFSTYMDDS------ 299
            .||||::|......:.||.....||.||           :.:..:.::..:.::::.||
Zfish   271 AWWLGYLIAGFITLLSAVPFWFLPKSLP-----------LPERRLSKYSPERNSFIKDSALLEHK 324

  Fly   300 --------------DFWPSLKRLFNNRLLMFNLLSIMCVQ-SAVVNYGLQEESYLQSRFFLPYNE 349
                          ||.|:|:.|..|. :.|..|.:..:| ::::.....:..|::..:
Zfish   325 YQADEPANFLEMAKDFLPTLRSLLGNP-VYFLYLCVTIIQFNSLIGMVTYKPKYIEQHY------ 382

  Fly   350 QDGLAAEWRSAFVSYFLKPPVMALGMLISGLVISKAKLSARKITG-INIALSIHLVAIFIGLIF- 412
              |.:|. ::.|:...:..|.:||||...|:::.|.|||   |.| ...||...|:..|:.|.|
Zfish   383 --GQSAS-KANFLMGVINIPAVALGMFSGGVIMKKFKLS---IMGAAKFALGTSLLGYFLSLFFF 441

  Fly   413 -VQCDVGAIAGV------------EGGKLKQPYCSSQCLCTPTAFMPVCPENSSVTYFSPCYAGC 464
             :.|:..::||:            ..|.|:.. |::.|.|....:.|||.|: .:||.|||.|||
Zfish   442 SMGCENASVAGITMSYNGTESLFMADGSLRAS-CNAACHCPEKNWDPVCGED-GLTYVSPCLAGC 504

  Fly   465 TKKTTINSFQLFEGCSCSGDQSLNSTGQMRATAGACSS-DNCQSAIIIFQIMSISVAFLMGVGAI 528
            ..........:||.|||.|      .|...||||.|:: ::|......|..:|:..:|::.:|..
Zfish   505 RTSHGSGMDTVFEQCSCIG------VGNQTATAGQCNNRESCHRIFPYFLALSVITSFIISLGGT 563

  Fly   529 GKTLITLRAVLPQDKSLALAFELMIVGLFAYVPVHLSYDIVTRTTCVYWAPNYERC 584
            ...::.:|.:.||.|||||.|..:.....|.:|..:.:..:..|||:.|  .:::|
Zfish   564 PGYMLLIRCIKPQLKSLALGFHTLTTRTLAGIPAPIYFGAIIDTTCLKW--GHKKC 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Eb	NP_609570.1	oat	23..619	CDD:273279	147/637 (23%)
		MFS	50..>267	CDD:119392	55/254 (22%)
		KAZAL_SLC21	430..483	CDD:238650	20/52 (38%)
slco1c1	XP_005164528.1	OATP	48..631	CDD:281175	144/612 (24%)
		MFS	50..461	CDD:119392	93/442 (21%)
		KAZAL_SLC21	470..523	CDD:238650	21/54 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810