Protein Alignment Oatp33Eb and Slco1a1

DIOPT Version :9

• Sequence 1: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_058807.1
• Gene: Slco1a1 / 50572
• RGDID: 3700
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 148/610 - (24%)
• Similarity: 255/610 - (41%)
• Gaps: 122/610 - (20%)

  Fly    43 YARLRTFILVL-------AISGTLQGA----CESYFRVSAKQA-----SFQFGWNPLIVDWLLVA 91
            :::::.|:|.|       ::||....:    .|..|.:|...|     ||:.|
  Rat    16 FSKMKVFLLSLTCACLTKSLSGVYMNSMLTQIERQFDISTSVAGLINGSFEIG------------ 68

  Fly    92 SGLFQAVFALAFAYWADVYHPIKWLVGTLMLQAVTCVVAVIPSIMNFADGNQAKDALLD--ANMC 154
             .||..||...|.  ..::.|:...:|.::: .:.|::..:|   :|..|....:..:.  .|:.
  Rat    69 -NLFFIVFVSYFG--TKLHRPVVIGIGCVIM-GLGCLLMSLP---HFFMGRYEYETTISPTGNLS 126

  Fly   155 ATSLAQFQRLTLT----------EAQSSSLTLAMLFVLQLALGMGGLAYYTLGVSYIDDNSLSQD 209
            :.|....:..|.|          ..:..||....:.|..:..|:|......||:|||:|.:.|::
  Rat   127 SNSFLCMENRTQTLKPTQDPAECVKEMKSLMWICVMVGNIIRGIGETPIVPLGISYIEDFAKSEN 191

  Fly   210 SPAVIG----AALAARVFGQQAGSF---LVLGVGLTH-------------VG-WWLGWVILA--- 250
            ||..||    ..:|..:||...||:   :.:.:|..:             || ||:|:::.|
  Rat   192 SPLYIGILEMGKVAGPIFGLLLGSYCAQIYVDIGSVNTDDLTITPSDTRWVGAWWIGFLVCAGVN 256

  Fly   251 -----PFIFVGAVLLGLFPKRLPKTVIHQAAQRIIEQSSMRRFGSQF--STYMDDSDFWPSLKRL 308
                 ||.|:        ||.|||.. .|....:.:...:.::|.|.  .......||...:|||
  Rat   257 ILTSIPFFFL--------PKALPKKG-QQENVAVTKDGKVEKYGGQAREENLGITKDFLTFMKRL 312

  Fly   309 FNNRLLMFNLLSIMCVQSAVVNYGLQEESYLQSRFFLP-YNEQD-GLAAEWRSAFVSYFLKPPVM 371
            |.|.:.|..:|:.:          ||...::....||| |.||. |.:.......:..:..||:
  Rat   313 FCNPIYMLFILTSV----------LQVNGFINKFTFLPKYLEQQYGKSTAEAIFLIGVYSLPPI- 366

  Fly   372 ALGMLISGLVISKAKLSARKITGINIALSIHLVAIFIGLIFVQCDVGAIAG-------------V 423
            .||.||.|.::.|.|::.:|...:...||:....:|:....:.||..|:||             |
  Rat   367 CLGYLIGGFIMKKFKITVKKAAYLAFCLSVFEYLLFLCHFMLTCDNAAVAGLTTSYKGVQHQLHV 431

  Fly   424 EGGKLKQPYCSSQCLCTPTAFMPVCPENSSVTYFSPCYAGCTKKTTINSFQLFEGCSCSGDQSLN 488
            |...|..  |:::|.|:...:.|||.:| .|.|.|.|.|||.|.....:..:|:.|||     :.
  Rat   432 ESKVLAD--CNTRCSCSTNTWDPVCGDN-GVAYMSACLAGCKKFVGTGTNMVFQDCSC-----IQ 488

  Fly   489 STGQMRATAGAC-SSDNCQSAIIIFQIMSISVAFLMGVGAIGKTLITLRAVLPQDKSLALAFELM 552
            |.|...|..|.| ....|.:.:..|.|::|.::|:..:.||...::.||.|..::|||.:.....
  Rat   489 SLGNSSAVLGLCKKGPECANRLQYFLILTIIISFIYSLTAIPGYMVFLRCVKSEEKSLGVGLHTF 553

  Fly   553 IVGLFAYVPVHLSYDIVTRTTCVYW 577
            .:.:||.:|..:.:..:...||::|
  Rat   554 CIRVFAGIPAPVYFGALIDRTCLHW 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Eb	NP_609570.1	oat	23..619	CDD:273279	148/610 (24%)
		MFS	50..>267	CDD:119392	59/273 (22%)
		KAZAL_SLC21	430..483	CDD:238650	19/52 (37%)
Slco1a1	NP_058807.1	oat	1..625	CDD:273279	148/610 (24%)
		MFS	40..>408	CDD:119392	92/406 (23%)
		KAZAL_SLC21	436..488	CDD:238650	20/59 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	645..670

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810