Protein Alignment Oatp33Eb and Slco1a4

DIOPT Version :9

• Sequence 1: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_001342506.1
• Gene: Slco1a4 / 28250
• MGIID: 1351896
• Length: 670
• Species: Mus musculus
• Alignment Length: 611
• Identity: 150/611 - (24%)
• Similarity: 260/611 - (42%)
• Gaps: 116/611 - (18%)

  Fly    39 GCQKYARLRTFILVLA---ISGTLQGACESYFRVSAKQASFQFGWNPLIVDWLLVASGLFQ---A 97
            |.:.:::::.|:|.|.   :|.:|.|   :|......|...|||....:|.   :.:|.|:   .
Mouse    12 GVRCFSKIKAFLLALTCAYVSKSLSG---TYMNSMLTQIERQFGIPTSVVG---LINGSFEIGNL 70

  Fly    98 VFALAFAYWADVYH-PIKWLVGTLMLQAVTCVVAVIPSIMNFADGNQAKDAL------LDAN--M 153
            :..:..:|:....| ||...||..:: .:.|.:..||   :|..|....:..      |.:|  :
Mouse    71 LLIIFVSYFGTKLHRPIMIGVGCAVM-GLGCFLISIP---HFLMGRYEYETTILPTSNLSSNSFV 131

  Fly   154 CATSLAQFQRLTL--TEAQSSSLTLAMLFVL--QLALGMGGLAYYTLGVSYIDDNSLSQDSPAVI 214
            |..:..|..:.|.  ||......:|..::||  .:..|||......||:|||:|.:.|::||..|
Mouse   132 CTENRTQTLKPTQDPTECVKEMKSLMWIYVLVGNIIRGMGETPIMPLGISYIEDFAKSENSPLYI 196

  Fly   215 GAALAARVFGQQAGSFLVLGVGLTHV-----------------------GWWLGWVILA------ 250
            |........|...|  |:||....::                       .||:|:::.|
Mouse   197 GILETGMTIGPLIG--LLLGSSCANIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILT 259

  Fly   251 --PFIFVGAVLLGLFPKRLPKTVIH---QAAQRIIEQSSMRRFGSQFSTYMDDSDFWPSLKRLFN 310
              ||.|        |||.|.|..:.   ...:...|:....:...:....  ..||:..:|.|..
Mouse   260 SIPFFF--------FPKTLLKEGLQDNGDGTENAKEEKHREKIKEENRGI--TKDFFLFMKSLSC 314

  Fly   311 NRLLM-FNLLSIMCVQSAVVNYGLQEESYLQSRFFLP-YNEQD-GLAAEWRSAFVSYFLKPPVMA 372
            |.:.| |.|:|:           :|..:::.|..|:| |.||. |.:.......:..::.||: .
Mouse   315 NPIYMIFILISV-----------IQVNAFINSFTFMPKYLEQQYGKSTAEIVFLMGLYMLPPI-C 367

  Fly   373 LGMLISGLVISKAKLSARKITGINIALSI--HLVAIFIGLIFVQCDVGAIAGV----EGGKLKQP 431
            ||.||.||::.|.|::.:|...|...||:  :|:: |:..| :.||...:||:    ||  ::.|
Mouse   368 LGYLIGGLIMKKFKITVKKAAYIGFWLSLTEYLLS-FVSYI-MTCDNFPVAGLTTSYEG--VQHP 428

  Fly   432 Y---------CSSQCLCTPTAFMPVCPENSSVTYFSPCYAGCTKKTTINSFQLFEGCSCSGDQSL 487
            .         |:::|.|....:.|||.:| .::|.|.|.|||.|.....:..:|:.|||     :
Mouse   429 LYVENNVLADCNTKCSCLTNTWDPVCGDN-GLSYMSACLAGCEKSVGTGTNMVFQNCSC-----I 487

  Fly   488 NSTGQMRATAGAC-SSDNCQSAIIIFQIMSISVAFLMGVGAIGKTLITLRAVLPQDKSLALAFEL 551
            .|:|...|..|.| ....|.:.:..|.|:||...|:..:|||...::.||.:..::|||.:....
Mouse   488 QSSGNASAVLGLCDKGPECANKLQYFLIISIIGCFIFSLGAIPGYMVLLRCMKSEEKSLGVGLHT 552

  Fly   552 MIVGLFAYVPVHLSYDIVTRTTCVYW 577
            ..:.:...:|..:.:..:...||::|
Mouse   553 FCMRILGGIPAPIYFGALIDRTCLHW 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Eb	NP_609570.1	oat	23..619	CDD:273279	150/611 (25%)
		MFS	50..>267	CDD:119392	63/266 (24%)
		KAZAL_SLC21	430..483	CDD:238650	19/61 (31%)
Slco1a4	NP_001342506.1	oat	1..625	CDD:273279	150/611 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	649..670

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810