Protein Alignment Oatp33Eb and Slco1a1

DIOPT Version :9

• Sequence 1: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_038825.1
• Gene: Slco1a1 / 28248
• MGIID: 1351891
• Length: 670
• Species: Mus musculus
• Alignment Length: 605
• Identity: 147/605 - (24%)
• Similarity: 251/605 - (41%)
• Gaps: 112/605 - (18%)

  Fly    43 YARLRTFILVLAISGTLQGACESYFRVSAKQASFQFGWNPLIVDWLLVASGLFQ------AVFAL 101
            :::::.|::.|..:...:.....|......|...|||....:|.::   :|.|:      .||..
Mouse    16 FSKMKVFLMSLTCAYLAKSLSGVYMNSMLTQIERQFGIPTSVVGFI---TGSFEIGNLLLIVFVS 77

  Fly   102 AFAYWADVYHPIKWLVGTLMLQAVTCVVAVIPSIMNFADGNQAKDALLD--ANMCATSLAQFQRL 164
            .|.  ..::.||...||.::: .:.|.:...|   :|..|....:..:.  :|:.:.|....:..
Mouse    78 YFG--RKLHRPIIIGVGCVVM-GLGCFLMASP---HFLMGRYKYETTISPTSNLSSNSFLCIENR 136

  Fly   165 TL--------TEAQSSSLTLAMLFVL--QLALGMGGLAYYTLGVSYIDDNSLSQDSPAVIG---- 215
            |.        ||......:|..::||  ....|:|......||:|||:|.:.|::||..||
Mouse   137 TQTLKPTQDPTECVKEIKSLMWIYVLIGNTMRGIGETPIMPLGISYIEDFAKSENSPLYIGILEM 201

  Fly   216 AALAARVFGQQAGSF---LVLGVGLTH-------------VG-WWLGWVILA--------PFIFV 255
            ..:...:.|...|||   :.:.:|..:             || ||:|:::.|        ||.|
Mouse   202 GKIVGPIIGLLLGSFFARVYVDIGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSIPFFF- 265

  Fly   256 GAVLLGLFPKRLPKTVI--------HQAAQRIIEQSSMRRFGSQFSTYMDDSDFWPSLKRLFNNR 312
                   |||.|||..:        ::..::..|::.....|.       ..||.|.:|.|..|.
Mouse   266 -------FPKTLPKKELQDNVDVTKYEKVEKHRERAKKENLGI-------TKDFLPFMKSLCCNP 316

  Fly   313 L-LMFNLLSIMCVQSAVVNYGLQEESYLQSRFFLP-YNEQD-GLAAEWRSAFVSYFLKPPVMALG 374
            : ::|:|.|:           ||...:..:..||| |.||. |.:.......:..:..||| .||
Mouse   317 IYMLFSLTSV-----------LQINGFASTFTFLPKYLEQQYGKSTSEAVFLIGVYSLPPV-CLG 369

  Fly   375 MLISGLVISKAKLSARKITGINIALSIHLVAIFIGLIFVQCDVGAIAGVE-----------GGKL 428
            .||||.::.|.|::.:|...|...||:....||:....:.||...:||:.           |.|.
Mouse   370 YLISGFIMKKFKITVKKAAYIAFGLSLSEYFIFLCNYLLTCDNFPVAGLTTSYKGVQHPLYGEKN 434

  Fly   429 KQPYCSSQCLCTPTAFMPVCPENSSVTYFSPCYAGCTKKTTINSFQLFEGCSCSGDQSLNSTGQM 493
            ....|:::|.|....:.|||.:| .:.|.|.|.|||.|.....:..:|:.|||.|     |:|..
Mouse   435 VLADCNTRCSCLTDTWDPVCGDN-GLAYMSACLAGCEKSVGTGTNMVFQNCSCIG-----SSGNS 493

  Fly   494 RATAGAC-SSDNCQSAIIIFQIMSISVAFLMGVGAIGKTLITLRAVLPQDKSLALAFELMIVGLF 557
            .|..|.| ....|.:.:..|.|.|:..:|:..:.||...::.||.|..::||:.:......:.|.
Mouse   494 SAVLGLCKKGPECDNKLQYFLIKSVFSSFIFSLAAIPGYMVLLRCVKSEEKSIGVGLHAFFIRLL 558

  Fly   558 AYVPVHLSYDIVTRTTCVYW 577
            |.:|..:.:..:...||::|
Mouse   559 AGIPAPVYFGALIDRTCLHW 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Eb	NP_609570.1	oat	23..619	CDD:273279	147/605 (24%)
		MFS	50..>267	CDD:119392	58/263 (22%)
		KAZAL_SLC21	430..483	CDD:238650	18/52 (35%)
Slco1a1	NP_038825.1	oat	1..625	CDD:273279	147/605 (24%)
		MFS	23..>396	CDD:119392	95/408 (23%)
		KAZAL_SLC21	436..488	CDD:238650	18/52 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810