Protein Alignment Oatp33Eb and Slco2a1

DIOPT Version :10

• Sequence 1: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_073158.2
• Gene: Slco2a1 / 24546
• RGDID: 3051
• Length: 644
• Species: Rattus norvegicus
• Alignment Length: 592
• Identity: 142/592 - (23%)
• Similarity: 246/592 - (41%)
• Gaps: 87/592 - (14%)

  Fly    43 YARLRTFILVLAISGTLQGACESYFRVSAKQASFQFGWNPLIVDWLLVASGLFQAVFALAFAYWA 107
            ::.::.|:|...:....|....:||:.|......:||.:......:...:.:..|...:..:|:.
  Rat    28 FSNIKVFVLCHGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNATLIIFISYFG 92

  Fly   108 D-VYHPIKWLVGTLMLQAVTCVVAVIPSIM-------NFADGNQAKDALLDANMCATSLAQF--- 161
            . |..|....:|.|:| |....|..:|..:       :..|||::.   ...::|...|...
  Rat    93 SRVNRPRMIGIGGLLL-AAGAFVLTLPHFLSEPYQYTSTTDGNRSS---FQTDLCQKHLPALPPS 153

  Fly   162 ---QRLTLTEAQSSSLTLAMLFVLQLALGMGGLAYYTLGVSYIDDNSLSQDSPAVIGAALAARVF 223
               ..:..|..::||| ..::.|.||..|:|.:.....|:||:||.:...:||..|....|..||
  Rat   154 KCHSTVPDTHKETSSL-WGLMVVAQLLAGIGTVPIQPFGISYVDDFAEPTNSPLYISILFAIAVF 217

  Fly   224 GQQAGSFLVLGVGLTHV-----------------------GWWLGWVILAPFIFVGAVLLGLFPK 265
            |...|  .:||..:..:                       .||||.:|.:.|:.|.::....||:
  Rat   218 GPAFG--YLLGSVMLRIFVDYGRVDTATVNLSPGDPRWIGAWWLGLLISSGFLIVTSLPFFFFPR 280

  Fly   266 RLPKTVIHQAAQRII--EQSSMRRFGSQFSTYMDDSDFWPSL-KRLFNNRLLMFNLLSIMCVQSA 327
            .:.:     .|:|.:  |::..........:.||....:|.: .||..|.|.|..:|| .|..|:
  Rat   281 AMSR-----GAERSVTAEETMKTEEDKSRGSLMDFIKRFPRIFLRLLMNPLFMLVVLS-QCTFSS 339

  Fly   328 VVNYGLQEESYLQSRFFLPYNEQDGLAAEWRSAFVSYFLKPPVMALGMLISGLVISKAKLSARKI 392
            |: .||   |...::|.   .:|.|..|.:.: |:...:..|..|||||..|:::.:.....:.|
  Rat   340 VI-AGL---STFLNKFL---EKQYGATAAYAN-FLIGAVNLPAAALGMLFGGILMKRFVFPLQTI 396

  Fly   393 TGINIALSIHLVAIFIGLIFVQCDVGAIAGVEGGKL-------KQPYCSSQCLCTPTAFMPVCPE 450
            ..:...:....:.:.:.|.|:.|...|:|.|.....       :.|.|...|.|..:.|.|||.:
  Rat   397 PRVAATIITISMILCVPLFFMGCSTSAVAEVYPPSTSSSIHPQQPPACRRDCSCPDSFFHPVCGD 461

  Fly   451 NSSVTYFSPCYAGCTKKTTINSFQ---LFEGCSCSGDQSLNSTGQMRATAGACSSDNCQSAIIIF 512
            | .|.|.|||:|||:...|.:...   ::..|||.      |.|...|..|:|.:...|  :::.
  Rat   462 N-GVEYVSPCHAGCSSTNTSSEASKEPIYLNCSCV------SGGSASAKTGSCPTSCAQ--LLLP 517

  Fly   513 QIMSISVAFLMGVGAIGKT---LITLRAVLPQDKSLALAFELMIVGLFAYVPVHLSYDIVTRTTC 574
            .|..||.|.|  :..|...   ::.||.|...:||.|:..:.:::.|.|::|....|.::..::|
  Rat   518 SIFLISFAAL--IACISHNPLYMMVLRVVNQDEKSFAIGVQFLLMRLLAWLPAPSLYGLLIDSSC 580

  Fly   575 VYWAPNY 581
            |.|  ||
  Rat   581 VRW--NY 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Eb	NP_609570.1	MFS_SLCO_OATP	46..536	CDD:340894	127/542 (23%)
		PHA03247	<635..813	CDD:223021
Slco2a1	NP_073158.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		MFS_SLCO2A_OATP2A	30..542	CDD:341019	127/543 (23%)