Protein Alignment Oatp33Eb and Y70G10A.3

DIOPT Version :9

• Sequence 1: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_499267.1
• Gene: Y70G10A.3 / 190573
• WormBaseID: WBGene00013499
• Length: 690
• Species: Caenorhabditis elegans
• Alignment Length: 698
• Identity: 150/698 - (21%)
• Similarity: 262/698 - (37%)
• Gaps: 161/698 - (23%)

  Fly    22 DDSVDCGIKGLGWCRGPGCQKYARLRTFILVLAISGTLQ------------GACESYFRVSAKQA 74
            :|..:..:.|.|.|.....|.:...:..::||.|...:|            ...|..|::::...
 Worm    23 EDDAEKLLCGYGACTPSWLQGFHNAKCLLVVLGICAFIQSFVVNAIFPVGLSTLERRFKMTSTHT 87

  Fly    75 SFQFGWNPLIVDWLLVASGLFQAVFALAFAYWADVYHPIKWLVGTLMLQAVTCVVAVIP------ 133
            .....|....|  |||       ||.:  .:|.:..|..:|:....::.|:..::..:|
 Worm    88 GIISSWYDFAV--LLV-------VFPV--CHWGNNGHKGRWIGWGGVIMALGSLICALPHWMVDI 141

  Fly   134 ------SIMNFADGNQAKDALLDANMCATSLAQFQRLTLTEAQSSSLT-LAMLFVL-QLALGMGG 190
                  .:.|..|..|.  |..|...||           .:..||... ...:|:| |...|:|.
 Worm   142 YHPDVNDLTNQTDFGQC--ANRDDPECA-----------GKPHSSWFNPYFWMFILGQTLHGVGS 193

  Fly   191 LAYYTLGVSYIDDNSLSQDSPA--VIGAALAA--RVFGQQAGSFLV------------------- 232
            ...:::|.:|:|:|...:.||.  .|.|.|.:  .|.|..||.||:
 Worm   194 TPLFSIGTTYMDENVSQKASPVYLAIHAVLTSFGPVIGVFAGGFLLNLYDDFDRVERIPMERSDP 258

  Fly   233 LGVGLTHVGWWLGWVILAPFIFVGAVLLGL----FPKRLPKTVIHQAAQRIIEQSSMRRFGSQFS 293
            ..||    .||:|::|.:    :.|:::..    |.:.||:...|:|  :.:.|
 Worm   259 RWVG----AWWVGFIISS----ISALMIAFPILAFARELPEAKRHRA--KDVNQ----------- 302

  Fly   294 TYMDDSDFWPSLKR-LFNNRLLMFNLLS----IMCVQSAVVNYGLQEESYLQSRF--FLPYNEQD 351
            .::.:.|......| |......::.:||    ::|:...:.      ||.:.:.|  |:|...:.
 Worm   303 CHVANGDVNAKAPRDLMKLPACVWKILSNPTFLVCIFVGIF------ESIIINGFAAFMPKILET 361

  Fly   352 GLA-----AEWRSAFVSYFLKPPVMALGMLISGLVISKAKLSARKITGINIALSIHLVAIFIGLI 411
            .|:     |.:.|:.|.:     ..|.|:::.|.:|.:.||....:..:.|...:..:....||:
 Worm   362 LLSTNPTLASYLSSVVIF-----AAATGVMVGGTIIRQLKLQVGGMLKMIIVCHVFALLFTTGLL 421

  Fly   412 FVQCD----VGAIAGVEGGKLKQPY-------CSSQCLCTPTAFMPVCPENSSVTYFSPCYAGCT 465
             ..|.    ||...|.|...:::.:       |::.|.| ...:.|||..|:...|:|.|:||||
 Worm   422 -SHCPQREFVGINLGYEDLSIEKMHDFSISSTCNADCHC-KMEWNPVCDRNTGHMYYSACHAGCT 484

  Fly   466 KKTTINSFQLFEGCSCSGDQS---------------LNSTGQMRATAGACSSDNCQSAIIIFQIM 515
            .:|||:....:.||.|....|               ||.        |.|..|......|:...:
 Worm   485 GRTTIDGSSQWSGCGCLTSNSTFHNLIHGIKEHPDVLNQ--------GYCHQDCGYREYILMVTL 541

  Fly   516 SISVAFLMGVGAIGKTLITLRAVLPQDKSLALAFELMIVGLFAYVPVHLSYDIVTRTTCVYWAPN 580
            .|:|......| |....|.||.|....::|||......|.|..::|..:.:.|:..|.|:.|..:
 Worm   542 FITVVASFASG-IPTQQIMLRVVPFDQRTLALGVNWTFVRLLGFIPGGILFGIIIDTACLEWGES 605

  Fly   581 YER---CLLRETPKHGNILDILTASLILASVLFDILVYIFAKGLNLYN 625
            ..:   ||:.:..|....:..|.....|.|:|..|:.|:..:..:|.|
 Worm   606 CGKATSCLVYDPFKLSWTITGLAIVCKLLSILATIIGYMTYRPSDLDN 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Eb	NP_609570.1	oat	23..619	CDD:273279	148/689 (21%)
		MFS	50..>267	CDD:119392	55/269 (20%)
		KAZAL_SLC21	430..483	CDD:238650	20/59 (34%)
Y70G10A.3	NP_499267.1	OATP	49..620	CDD:281175	136/637 (21%)
		MFS	51..>421	CDD:119392	83/425 (20%)
		KAZAL_SLC21	449..500	CDD:238650	19/51 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4629
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.760