Protein Alignment Oatp33Eb and F47E1.2

DIOPT Version :10

• Sequence 1: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_509531.1
• Gene: F47E1.2 / 181145
• WormBaseID: WBGene00018566
• Length: 744
• Species: Caenorhabditis elegans
• Alignment Length: 508
• Identity: 132/508 - (25%)
• Similarity: 220/508 - (43%)
• Gaps: 82/508 - (16%)

  Fly   168 EAQSSSLTLAMLFVLQLALGMGGLAYYTLGVSYIDDNSLSQDSPAVIGAALAARVF----GQQAG 228
            |..|:|....:.|...|.||:|....::|||..:|||...:..||..||..:.||.    |...|
 Worm   255 EQTSNSYPFLVFFFSLLLLGIGRTVPWSLGVPLLDDNIKKKSLPAYFGAISSIRVLGPICGYMIG 319

  Fly   229 SF-------LVLGVGLTHV------GWWLGWVILAPFIFVGAVLLGLFPKRLPKTVIH------- 273
            ||       |....|||..      .||:|      |:|:|::.|      .|.|::.
 Worm   320 SFCNKFYYTLNPPNGLTPADPTWIGAWWMG------FLFIGSIAL------FPSTMLFFFPQGKE 372

  Fly   274 ---QAAQ-RIIEQSSMRRFGSQFSTY-MDDSDFWPSLKRLFNNRLLMFNLLSIMCVQSAVVNYGL 333
               .|.| |.:.:..:::...:..|. |...||..|.|::.:.::.|.::|..:|...|...|.:
 Worm   373 GDGSAVQLRDVHKEKLKKSVDEDRTITMKLKDFAKSCKKVLSTKIYMGSVLGRVCDVLAFKGYIV 437

  Fly   334 QEESYLQSRFFLPYNEQDGLAAEWRSAFVSYFLKPPVMALGMLISGLVISKAKLSARKITGINIA 398
            ....||::.|.:|    ..|...:.:.|..:     ...||:...|.|..|.||:.|:.....:.
 Worm   438 FLPKYLENHFGIP----QYLVHRYMAMFGVF-----GFGLGVATGGYVTKKLKLNGRRAAMFVML 493

  Fly   399 LSIHLVAIFIGLIFVQCDVGAIAGVEGGKLKQP------YCSSQCLCTPTAFMPVCPENSSVTYF 457
            :|...|.::.|.||:.|:  :|....|...:|.      .|:|||.|......||| :.:...||
 Worm   494 MSTLNVCLYSGKIFIGCE--SIVNSIGSNNRQTNYNFTRECNSQCSCENARLYPVC-DQTGFAYF 555

  Fly   458 SPCYAGCTKKTTINSFQL--FEGCSCSGDQSLNSTGQMRATAGACS----SDNCQSAIIIFQIMS 516
            |||:|||.:.....|..:  |..|.|             |..|..|    .:.|:::.:||.:..
 Worm   556 SPCHAGCREAMQYGSDPVLDFTSCQC-------------APGGVVSKKFCENTCKTSSVIFFLTV 607

  Fly   517 ISVAFLMGVGAIGKTLITLRAVLPQDKSLALAFELMIVGLFAYVPVHLSYDIVTRTTCVYW--AP 579
            :..:|:.|:|.:...||.||:|.|:.:||:|..:.|.|.||..:|..:.:.:|....|:.|  |.
 Worm   608 LPGSFVAGLGVVPAMLILLRSVPPETRSLSLGLQGMAVSLFGTLPSPILWGLVIDAACLVWDKAC 672

  Fly   580 NYER--CLLRETPKHGNILDILTASLILASVLFDILVYIFAKGLNLYNCKVTD 630
            |..|  |.:....:....:.:|...:...:::.|:.|:..||.||:.:..|::
 Worm   673 NGARGSCSIYHPDRLRVWMHLLYVVIRTVALITDVYVWKHAKNLNIMDEPVSE 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Eb	NP_609570.1	MFS_SLCO_OATP	46..536	CDD:340894	105/408 (26%)
		PHA03247	<635..813	CDD:223021
F47E1.2	NP_509531.1	AraJ	8..>93	CDD:442063
		oat	95..715	CDD:273279	128/496 (26%)