Protein Alignment Oatp33Eb and Y32F6B.1

DIOPT Version :10

• Sequence 1: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: NP_505689.2
• Gene: Y32F6B.1 / 179463
• WormBaseID: WBGene00012531
• Length: 760
• Species: Caenorhabditis elegans
• Alignment Length: 625
• Identity: 141/625 - (22%)
• Similarity: 244/625 - (39%)
• Gaps: 153/625 - (24%)

  Fly   106 WADVYHPIKWLVGTLMLQAVTCVVAVIPS---IMNFADGNQAKDAL------------------- 148
            |.:..||:                 :.|.   :||: :|::..|.|
 Worm   132 WLEQIHPL-----------------IDPKNQVVMNY-EGDEKSDLLQKYVEYCHYHKGSEICKNL 178

  Fly   149 ----------LDANM-------------CATSL--AQFQRLTLTEAQSSSLTLAMLFVLQLALGM 188
                      .||.|             |.:.|  .:.|.....:.||:.....|:|...|.||:
 Worm   179 EKYIAEKFPITDAKMSNVRAMVALPYGFCHSMLNFVRAQHYACKKDQSTLGPFMMIFGGLLVLGV 243

  Fly   189 GGLAYYTLGVSYIDDNSLSQDSPAVIGAALAARVFGQQAGSFLVLG-------------VGLTHV 240
            |....::||:..:|||...|:.|.........::.|...|  |::|             .|||.:
 Worm   244 GRTMPFSLGLPLMDDNVKKQNLPLYFSFMFFVKILGPVIG--LLVGGQLNKLYVDFNPPQGLTPL 306

  Fly   241 G------WWLGWVILAPFIFVGAVLLGLFP----------------KRLPKTVIHQAAQRIIEQS 283
            .      ||||::|....:|..:::|..||                |..|:..::...:.|.:..
 Worm   307 DPMWIGCWWLGFLIFGTLLFGPSLVLYFFPSDDLDINAPEEFDDDGKVKPRKRLNLVDRHIKKDE 371

  Fly   284 SMRRFGSQF--STYMDD-SDFWPSLKRLFNNRLLMFNLLSIMCVQSAVVNYGLQEESYLQSRFFL 345
            .    |:..  .|.||. :||..::..|..|::.:..:...:....|...|.:.:..||:.:|.:
 Worm   372 Q----GNALMPETIMDKINDFKATIANLVKNKIFVGAMFGRIIDVLAFKGYFVFQAKYLELQFGV 432

  Fly   346 P-YNEQDGLAAEWRSAFVSYFLKPPVMALGMLISGLVISKAKLSARKITGINIALSIHLVAIFIG 409
            | |..|..:|:   :..|.:       |.|:::..|.:...||..||........|  |||..|.
 Worm   433 PQYRIQRYIAS---TGIVGF-------ACGVILGSLSMKFLKLQGRKAAAWVAVCS--LVAALIS 485

  Fly   410 LIFVQCDVG--AIAGVEGGKLK--QPY---CSSQCLCTPTAFMPVCPENSSVTYFSPCYAGC--- 464
              |....||  ::.|..|.::|  .|.   |...|:|..|...|||..:.| .|:|||:|||
 Worm   486 --FANGTVGCKSVIGQIGDQIKINGPVFDGCRDDCMCEQTPLYPVCDVSGS-AYYSPCHAGCAMG 547

  Fly   465 --------TKKTTINSFQLFEGCSCSGDQSLNSTGQMRATAGACSSDNCQSAIIIFQIMSISVAF 521
                    ..|.|:::. :||.|:|. |..:....:     ..|.::.|:.....|.:.....|.
 Worm   548 WKNYSIFDNTKATVDTL-IFENCACV-DNKVKEVSR-----SYCRTEECEERFGRFFMHQAFGAV 605

  Fly   522 LMGVGAIGKTLITLRAVLPQDKSLALAFELMIVGLFAYVPVHLSYDIVTRTTCVYWAPNYE---R 583
            ..|:|.:...||.||||.|:.:|::|.|...:|.|.|.:|..:.:..:...:|:.|..:.:   .
 Worm   606 FGGLGVVPGMLIVLRAVPPEHRSVSLGFNGFLVSLLATLPSPIIWGKIIDMSCLLWKKSCDSSGS 670

  Fly   584 CLLRETPKHGNILDILTASLILASVLFDILVYIFAKGLNL 623
            |.:.:|.:....|.::...|.:.|::.|:.|:.:|:||.|
 Worm   671 CSVYDTDELRVRLHVIYGCLRIFSLISDVWVWYWARGLKL 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Eb	NP_609570.1	MFS_SLCO_OATP	46..536	CDD:340894	116/533 (22%)
		PHA03247	<635..813	CDD:223021
Y32F6B.1	NP_505689.2	oat	4..706	CDD:273279	137/619 (22%)