Protein Alignment Oatp33Eb and Oatp26F

DIOPT Version :10

• Sequence 1: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: XP_061514349.1
• Gene: Oatp26F / 1275562
• VectorBaseID: AGAMI1_012141
• Length: 783
• Species: Anopheles gambiae
• Alignment Length: 738
• Identity: 169/738 - (22%)
• Similarity: 281/738 - (38%)
• Gaps: 165/738 - (22%)

  Fly    33 GW--CRGPGCQKYARLRTFILVLAISGTLQG-ACESYFRVSAKQASFQFGWNPLIVDWLLVASGL 94
            ||  .|....:::...:..:..|..:|.:|| ....:..|.......:||.......  |||||.
Mosquito    86 GWFALRPKWMERFMTPKWALFWLCWAGAVQGLVVNGFINVVITTIERRFGLRSTQTG--LVASGY 148

  Fly    95 FQAVFALAFAYWADVYHPIKWLVGTLMLQ---------AVTCVVAVIPSIMNFADGNQAKDALLD 150
            ..|.|....        |:.:..|.|...         ||..:.|.:.::.:|..| |.:....|
Mosquito   149 DIASFLCLV--------PVSYFGGRLGASKPRWIGWGVAVMGLGAFVFALPHFLVG-QYRATNSD 204

  Fly   151 ANMC--ATSL------AQFQRLT--------------------LTEAQSSSLTLAMLFVLQLALG 187
            .|:|  ||:|      |..:.||                    .:::::.|..:...|..||.||
Mosquito   205 QNVCTLATALVTNGTGASVEALTELVGCNHDTVSPLANGGQGPTSDSENLSWNVWFFFTAQLLLG 269

  Fly   188 MGGLAYYTLGVSYIDDNSLSQDSPAVIGAALAARVFGQQAGSFLVLG-----------------V 235
            .|....|||||:|||:|...:.|...:|......|.|..||  .|:|                 :
Mosquito   270 AGASPLYTLGVTYIDENVSKKMSSVYLGIYYTMAVVGPAAG--YVIGGQLLLFYTDMFVVDATTL 332

  Fly   236 GLT-H----VG-WWLGWVILAPFIFVGAVLLGLFPKRLPKTVIHQAAQRIIEQSSMRRFGSQFST 294
            ||| |    || ||:|:|.:|.|..:.||.:..:|..||      .::::.:.|...|.|
Mosquito   333 GLTPHSKVWVGAWWIGFVFMAAFCLLLAVPILAYPPALP------GSEKLQKVSEAHRGG----- 386

  Fly   295 YMDDSD------FWPSLKRLFNNRLLMFNLLSIMCVQSAVVNYGLQEESYLQSRFFLP--YNEQD 351
              ||.|      .:..:|::....|.:....:...:..|..:.||....:   ..|||  ...|.
Mosquito   387 --DDGDGERSQETFTKIKQIPRALLALLRNPTFFFLNLAGASEGLVISGF---AVFLPKLIENQF 446

  Fly   352 GLAAEWRSAFVSYFLKPPVMALGMLISGLVISKAKLSARKITGINIALSIHLVAIFIGLIFVQCD 416
            .:.|.| ||.:...:..|....|..:.|.::.|..||...|....:..:| ..|:|....|:.|.
Mosquito   447 SVTAVW-SALLMGIITVPAGGGGTFLGGYLVKKLHLSCSGIIKFCLFATI-FAALFTVCFFLSCP 509

  Fly   417 VGAIAGVEG-----GKLKQPY-------------------CSSQCLCTPTAFMPVCPENSSVTYF 457
            ....|||..     ..|..||                   |:.:|.|:...:.|:|..: .:.|:
Mosquito   510 NLTFAGVTAPYFPHENLDTPYARSTEPRDLYYLPKNLDNACNDRCACSRRNYEPICGAD-GIMYY 573

  Fly   458 SPCYAGCTKKTTINSFQLFEGCSCSGDQSLNST--GQMRATAGACSSD----NCQSA---IIIFQ 513
            |||:|||:::..:.:.:::..|:|     :|:|  |:..|..|..|.|    .|||.   :.||.
Mosquito   574 SPCHAGCSEEINLENAKVYRDCTC-----INATFHGEQSALYGGGSYDAVNTMCQSQCDHLWIFV 633

  Fly   514 IMSISVAFLMGVGAIGKTLITLRAVLPQDKSLALAFELMIVGLFAYVPVHLSYDIVTRTTCVYW- 577
            ::...|.|...:..:.....|||.|....:|.||..:.:.|.:...:|..:.:..:...||:.|
Mosquito   634 MLCFLVMFFTFLATMPALSATLRCVHDDQRSFALGIQWIKVRVLGTIPAPMIFGRLIDETCILWQ 698

  Fly   578 ---APNYERCLLRETPKHGNILDILTASLILASVLFDILVYIFAKGLNLYNC--KVTDNNYTPSL 637
               ..::..||:.:..       .::..::|.:::......:|..|...|..  |...|..|.:
Mosquito   699 ESSCDDHGACLVYDNA-------FMSKYMLLLALIGKACSILFFFGAWFYYIPPKTITNGDTAT- 755

  Fly   638 YAPIPHE---DATTSPS--APRG 655
                 |:   |:|||..  .|.|
Mosquito   756 -----HQKQTDSTTSQQKVPPNG 773

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Eb	NP_609570.1	MFS_SLCO_OATP	46..536	CDD:340894	139/591 (24%)
		PHA03247	<635..813	CDD:223021	7/26 (27%)
Oatp26F	XP_061514349.1	None