Protein Alignment Oatp33Eb and slco1e1

DIOPT Version :9

• Sequence 1: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: XP_009299376.1
• Gene: slco1e1 / 100332946
• ZFINID: ZDB-GENE-100818-2
• Length: 695
• Species: Danio rerio
• Alignment Length: 651
• Identity: 151/651 - (23%)
• Similarity: 261/651 - (40%)
• Gaps: 97/651 - (14%)

  Fly    38 PGCQKYARLRTFILVLAISGTLQGACESYFRVSAKQASFQFGWNPLIVDWLLVASGLFQAVF--- 99
            |.|   :.|:.||..|:.:...:..|.:|.:.:..|...:|       |....|.||....|
Zfish    27 PRC---SSLKIFIGALSFAYFSKTLCGTYMKSAITQIERRF-------DLSSSAVGLVDGSFEMG 81

  Fly   100 -----ALAFAYWADVYHPIKWLVGT-LMLQAVTCVVAVIPSIM----NFADGNQ--AKDALLDA- 151
                 |:...:.|.::.|  .|:|. ..|.|:...:..:|.:.    .|....|  |.:.::.|
Zfish    82 NLLFVAVVSHFGARLHRP--RLIGMGCFLMAIGSALTGLPHVFMGRYKFDTAIQGFANETVVIAP 144

  Fly   152 -----NMCATSLAQFQRLTLTEA---QSSSLTLAMLFVLQLALGMGGLAYYTLGVSYIDDNSLSQ 208
                 |....|:......|.|:.   ..||:.: .:|:.....|:|......||:|||||.:.::
Zfish   145 CQYPTNPSEHSIQHIDNTTGTDCVKDPGSSMWI-YVFLGNALRGIGETPVTPLGISYIDDFAKAE 208

  Fly   209 DSPAVIGA----ALAARVFGQQAGSF---LVLGVGLTHV--------------GWWLGWVILAPF 252
            :|...|..    .|...:||...||.   |.:.:|...|              .||||:.:.:.|
Zfish   209 NSAFYISCLQTIMLLGPMFGFLLGSMCAKLYVDIGFVSVDSVSITPQDARWVGAWWLGFFVSSAF 273

  Fly   253 IFVGAVLLGLFPKRLPKTVIHQAAQRIIEQSSMRRFGSQFST--YMDDSD----FWPSLKRLFNN 311
            :.:..|.....|:.|||.  .:..:.|.......:..|...|  .|..:|    |.||||||...
Zfish   274 LVLSGVPFWFLPRSLPKQ--GEEEKEICNTDDANKEHSVLQTTHTMTLADIAKGFLPSLKRLLCT 336

  Fly   312 RLLMFNLLSIMCVQSAVVNYGLQEESYLQSRFFLPYNEQDGLAAEWRSAFVSYFLKPPVMALGML 376
            ......|..|:...::.:.....:..|::.:|        |.:|. |:.|:...|..||:|:|:.
Zfish   337 PAYFLLLCGIVLKFNSFIGLLTFKAKYMEQQF--------GQSAS-RANFLIGVLILPVVAVGIF 392

  Fly   377 ISGLVISKAKLSARKITGINIALSIHLVAIFIGLIF--VQCDVGAIAGVEGGKLKQPY------- 432
            :.||::.:.|||.  :.|..::......|..:.|:.  .:||...:||:.......||
Zfish   393 LGGLLMKRYKLSV--VAGAQLSFITSFTAFLLLLLHFGTKCDNVPVAGLTVSYNGTPYMPSDQRS 455

  Fly   433 ----CSSQCLCTPTAFMPVCPENSSVTYFSPCYAGCTKKTTINSFQLFEGCSCSGDQSLNSTGQM 493
                |:..|.|:.:.:.||| .:|.:||.|||.||||..|......:|..|||....| .:.|..
Zfish   456 LESQCNQDCSCSTSEWDPVC-SDSGITYMSPCLAGCTASTGQGKNTVFHNCSCVLSPS-PAEGGR 518

  Fly   494 RATAGACSSDN-CQSAIIIFQIMSISVAFLMGVGAIGKTLITLRAVLPQDKSLALAFELMIVGLF 557
            ..:.|.|...: |..:...:..:|:..:|:..:|.....:|.:|.:.|:.|||||..:.:::...
Zfish   519 SVSLGQCPQGSACARSFTSYMAVSVLSSFINSLGTTPGYMIIIRCIAPELKSLALGIQTLVMRTL 583

  Fly   558 AYVPVHLSYDIVTRTTCVYW----APNYERCLLRETPKHGNILDILTASLILASVLFDILVYIFA 618
            ..:|..:.:..:..:.|:.|    ......|.:.::..:..|...||.:|...|..|.|.|.:..
Zfish   584 GGIPAPIYFGALIDSACLKWGLKKCGGRGACRIYDSNMYRVIFLSLTTALSGCSYFFIIAVIVLL 648

  Fly   619 K 619
            :
Zfish   649 R 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Eb	NP_609570.1	oat	23..619	CDD:273279	151/649 (23%)
		MFS	50..>267	CDD:119392	56/261 (21%)
		KAZAL_SLC21	430..483	CDD:238650	23/63 (37%)
slco1e1	XP_009299376.1	OATP	34..622	CDD:281175	140/612 (23%)
		MFS	36..>288	CDD:119392	56/261 (21%)
		KAZAL_SLC21	456..508	CDD:238650	20/52 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910