Protein Alignment CG5421 and ATP6AP1

DIOPT Version :10

• Sequence 1: NP_609569.1
• Gene: CG5421 / 34661
• FlyBaseID: FBgn0032434
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001174.2
• Gene: ATP6AP1 / 537
• HGNCID: 868
• Length: 470
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 63/337 - (18%)
• Similarity: 117/337 - (34%)
• Gaps: 106/337 - (31%)

  Fly   104 RVAEKTGDIIWHIPKISEMGSL-------EAEMELPCQKGEIHAFSFNDRNLLA-----HD---- 152
            |:..:....:|.:|.:....||       .||.::|.      ....:||:|.|     |:
Human    11 RMGPRCAQALWRMPWLPVFLSLAAAAAAAAAEQQVPL------VLWSSDRDLWAPAADTHEGHIT 69

  Fly   153 AAMAVATYQ--------------FSDCPVVHVYTAY-----TEEDKALQRRKSQKTQHMSIKNKI 198
            :.:.::||.              ..|...:..:|||     .::|.|..          :::|.:
Human    70 SDLQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFGNKQDSAFS----------NLENAL 124

  Fly   199 DGQPSN-----------SDTEVELQPHQISQSQADNMTVLRNEMIVLTFRSILLATKEQRSVLSP 252
            |..||:           |.....||....:.....::..||...:..:..::||       :..|
Human   125 DLAPSSLVLPAVDWYAVSTLTTYLQEKLGASPLHVDLATLRELKLNASLPALLL-------IRLP 182

  Fly   253 FNRTEVMLAQGREPLQVGLLNSHDIFGGIVMVLNTELGPLIVELI---PSQ------------GN 302
            :..:..::|    |.:| |..:.::.|.::..|.:|..|....|.   ||:            |.
Human   183 YTASSGLMA----PREV-LTGNDEVIGQVLSTLKSEDVPYTAALTAVRPSRVARDVAVVAGGLGR 242

  Fly   303 WYLTRM---------IFMNNTHYPRDLYFYGFEFSLCCTDITVYSSEASRLSFFDFHLDI---LW 355
            ..|.:.         :..|:| .|| :.|:...||:...|   ...:.:.|:|....|::   .|
Human   243 QLLQKQPVSPVIHPPVSYNDT-APR-ILFWAQNFSVAYKD---QWEDLTPLTFGVQELNLTGSFW 302

  Fly   356 QDKDNGLDLQYE 367
            .|....|.|.||
Human   303 NDSFARLSLTYE 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5421	NP_609569.1	None
ATP6AP1	NP_001174.2	VAS1_LD	265..405	CDD:461752	15/54 (28%)
		Ac45-VOA1_TM	420..458	CDD:466669