Protein Alignment Oatp33Ea and slco1f4

DIOPT Version :9

• Sequence 1: NP_001260417.1
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_001074135.2
• Gene: slco1f4 / 791184
• ZFINID: ZDB-GENE-070112-2172
• Length: 644
• Species: Danio rerio
• Alignment Length: 720
• Identity: 178/720 - (24%)
• Similarity: 303/720 - (42%)
• Gaps: 165/720 - (22%)

  Fly    32 ATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGG 96
            ::.|:|:.........::|:..|...|:|.:||||:|||.|.|.|....|:..:::..::||||.
Zfish    24 SSLKIFICALAFSYFSKSMTGSYTKSTITQIEKRFEIPSSTVGFIDGSFEMGNMLVITLVSYIGA 88

  Fly    97 QRNRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSLLNGTTGSDHSFQNISSVKT 161
            :.:||:.|..|::..|:...::..|||:.|          .|:.......|....:|..||:..:
Zfish    89 KFHRPKIIGAGVLLMGIGTLLMASPHFLMG----------RYKYGTAATHTNDAGNFTVISTCSS 143

  Fly   162 ER-------LCGVDKTEDDCDDLFSYVPLVLIFLSQFVLGVGNTLYYSLGQTYLDDNTKKTNTPL 219
            :.       ..|..|.|.:....:     |::.|...:.|:|......||.:::||..:..|:..
Zfish   144 DSQETLQQPFSGCQKEEAESSPFW-----VIVVLGNTMRGIGEASIVPLGMSFIDDYARPENSAF 203

  Fly   220 MLAVAMALRMIGPVVGFFFGFISLNTFID----PTKTPLIDSKDPRWLGAWWLGWVILGTLMCLF 280
            .:.....|:.|||:.|:..|.:..|.::|    ..::..|..:|.||:||||||:|:.|.|..|.
Zfish   204 YIGCLNTLKGIGPIFGYMLGSLCANLYVDFGLVDQESVTITPQDSRWVGAWWLGYVVSGLLTLLA 268

  Fly   281 SGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADL 345
            :......||.||:      ||.:.| |..|.::.|...:|:
Zfish   269 AFPFWFLPKVLPE------NSQISL-LDNTPQQHKTTPSLT------------------------ 302

  Fly   346 PKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGF---MTFLTKYMEVQFHKDAQSATIIVGPI 407
            ..:|||.....|||.||:.   ||...:.|:..:.|   .|:..||:|.||.:.|..|..::|..
Zfish   303 EIVKDFAPTFKRLLTNKIY---ILYLAYSIVAFNDFAIVATYTPKYLEQQFGQSASKANFLIGVT 364

  Fly   408 SIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGG-ISILGQISYAFLYCPNTFSMT-------- 463
            ||..:.:|:..||:::.:.|        |.::... :::|..::..||..| .|:::
Zfish   365 SIPAVALGVFLSGLMMKRFK--------WGLLASARVNLLTIVATVFLAVP-FFALSCENLDIAG 420

  Fly   464 -----------QAGQLNLTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCR-----GYNATS 512
                       |....::..:||.:|.|..:.:.|||.| ...|:.|.|||||.     |.|.|
Zfish   421 VTVPYQGSTEVQGVTSDVLPSCNADCGCPDLQWDPVCGE-NGVTYISPCHAGCNSTQGAGRNMT- 483

  Fly   513 KLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTR 577
              :.||.|:.:                                 .|:.:
Zfish   484 --FHDCRCIQS---------------------------------WGLSV---------------- 497

  Fly   578 RSTSDSVIRPGICTKN--CNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLAL 640
             ..|.:|:  |.|:::  ||...:.:.....:..:....|.:....::.|.|..|.||.:.|:.|
Zfish   498 -GNSSAVL--GQCSRDPKCNRMIYIYLGLQSLAFFLCGLGIIPFFTMSLRIVDPELKSLSVGMLL 559

  Fly   641 MMISLLALIPGPIIFGRLIDSTCLVW--TKTCNGNGNCQLYDQTRFRY-------SLNFLSCLLT 696
            :.:.:|..||.||.||.|||||||.|  .|:| |.|.|::||...||:       .|..|:|.|.
Zfish   560 LAVRVLGGIPAPIYFGALIDSTCLKWGQNKSC-GRGACRIYDIETFRFLFQGLTMCLRVLACSLL 623

  Fly   697 FMGLL 701
            ::..:
Zfish   624 WIATI 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_001260417.1	OATP	36..684	CDD:281175	171/690 (25%)
		MFS	40..>280	CDD:119392	66/250 (26%)
		DUF4064	364..447	CDD:290013	20/86 (23%)
		KAZAL_SLC21	470..521	CDD:238650	20/55 (36%)
slco1f4	NP_001074135.2	OATP	28..604	CDD:281175	171/690 (25%)
		MFS	30..>412	CDD:119392	111/439 (25%)
		KAZAL_SLC21	439..491	CDD:238650	21/55 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920