Protein Alignment Oatp33Ea and Slco6d1

DIOPT Version :10

• Sequence 1: NP_609568.3
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_011246380.1
• Gene: Slco6d1 / 70866
• MGIID: 1918116
• Length: 729
• Species: Mus musculus
• Alignment Length: 785
• Identity: 170/785 - (21%)
• Similarity: 296/785 - (37%)
• Gaps: 184/785 - (23%)

  Fly     5 KRRDPNRPPGHYLCGMANWHPPWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKI- 68
            |.:||:..|    .|:.:...|.||::...|.|:       |:..::.:...:....:::..|:
Mouse    58 KYKDPSEEP----YGLGSLVFPCLQRFNNVKSFL-------TLSFLAVVAHSMIFALVDQSIKLY 111

  Fly    69 -----PSQTTGIIL--SGNEISQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYG 126
                 ||:....::  |.|.:: .:.|:.:::.||:.||..|:|.|....|::..:..:|...:
Mouse   112 VAQLSPSRIEEYLMDTSDNFVA-FLFSMFVAHFGGRGNRANWVAAGCFLTGIAAIVFAVPFLNF- 174

  Fly   127 AGHEVLQFTKEYQDSLLNGTTGSDHSFQNISSVKTERLCGVDKTEDDCDDLFSYVPLVL------ 185
               |:::.                       ||..|.||...|....|:      |.||
Mouse   175 ---EIIKL-----------------------SVVKEELCEEGKLPKVCE------PTVLPHKSIC 207

  Fly   186 --IFL-SQFVLGVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFI 247
              ||: .|.:.|:.....|.|..:::.|:....::.|.:|:..|...:|..:||..|.::.....
Mouse   208 IFIFIFGQCLHGIAGLPLYILATSFIFDHVPTNSSGLYIALVDAALGVGYCLGFIGGMLNFKMSA 272

  Fly   248 DPTKTPLIDSKDPRWL-GAWWLGWVILGTL-MCLFSGLIGLFPKQLPKVNASR-TNSHLP----- 304
            ......:...:..|.| ..||..::.:... .|....|:| ||..||.....| ..|..|
Mouse   273 QEVMQAVGHRQRIRILQRGWWRTFIFVAVFAFCTTLPLLG-FPSSLPGARQIRLEKSQEPPTFDR 336

  Fly   305 -LALRQTKEELK---------REENLSLSSRFSSNA----ALDTIGAAAGANADLPKLKDFPRAL 355
             |..::.|..||         ...:|::.|:..|.:    ...|.|.|  .:.||.||...
Mouse   337 RLKNKEIKNNLKSVLHATWIYHRGHLTILSQTCSTSLGGICCSTTGKA--IDGDLQKLTQC---- 395

  Fly   356 MRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGLIGSG 420
              |:||.|::..::..............||.:|::.:|.....||:::.|...:.|.:.|....|
Mouse   396 --LIRNPLVLSQVVCKFTEFTTFKSSAVFLPQYLQTRFLIRPSSASMLTGVFILPGSIFGHFFGG 458

  Fly   421 MVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCP-NTFS-----MTQAGQL-NLTSNCNMNC 478
            .::.:.:.:....|.:.|:...:||:..:...|:.|. :.|:     ..:.|.: |||:.||:.|
Mouse   459 FIVHRMQMNNKNKLKFLVVASFVSIVLFLLTFFVECEISKFAGINDDYDRLGIIGNLTAPCNVPC 523

  Fly   479 SCEGISYTPVCHEPTDTTFFSACHAGCRGYNATSKL-----YEDCSCVVNDPAPKSAAQRLLNLL 538
            .|....|.|||.. .:|.:||.|.|||:   ||.||     |.:|||:
Mouse   524 GCTTSEYNPVCGR-DETQYFSPCFAGCK---ATKKLRKEKTYYNCSCI----------------- 567

  Fly   539 QPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTKNCNW--SFWAF 601
                             ..|:...|:.|.:.|.:              .|.|...|..  .|:||
Mouse   568 -----------------KEGLTTADNEGQYIDAV--------------SGTCNTRCLTLPLFFAF 601

  Fly   602 SITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVW 666
            ..|:..:|.|.|   :.:.|:..::|.....|.:.||...:......:|.||:|....|.||..|
Mouse   602 YFTATFLSSFCS---IPSALIVIQSVPTSWNSMSLGLMSTVWRFTGSVPAPILFAATSDFTCQFW 663

  Fly   667 -TKTCNGNGNCQLYDQTRFRYS----------LNFLSCLLTFMGLLFDYLVWYYGRNLDIYGDKE 720
             ...|.....|.:|:.....|:          |:.||||         |.|  |..:..:.||.:
Mouse   664 GINECGEKVRCWIYNTENLVYTFKTVWINMQILSGLSCL---------YGV--YRHDYVVKGDGK 717

  Fly   721 AKEEE 725
            ..||:
Mouse   718 KAEEK 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_609568.3	OATP	36..684	CDD:460821	148/701 (21%)
Slco6d1	XP_011246380.1	MFS	83..622	CDD:475125	134/643 (21%)