Protein Alignment Oatp33Ea and slco3a1b

DIOPT Version :9

• Sequence 1: NP_001260417.1
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_021333633.1
• Gene: slco3a1b / 570448
• ZFINID: ZDB-GENE-161017-34
• Length: 690
• Species: Danio rerio
• Alignment Length: 708
• Identity: 189/708 - (26%)
• Similarity: 291/708 - (41%)
• Gaps: 140/708 - (19%)

  Fly    45 GTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRNRPRWIAWGIV 109
            ||:.|    |.:..|||||:||.:.|...|:|.|..||..:.|.|.:||.|.:.:|||.|..|.:
Zfish    40 GTVGA----YLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARAHRPRLIGCGGI 100

  Fly   110 FCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSLLNGTTGSDHSF---QNISSVKTER-------L 164
            ...|...:..||.|:          |.:||..     ||.....   ||:.|..:..       :
Zfish   101 VMALGALLSALPEFL----------THQYQYQ-----TGESRPVGQGQNVCSNSSRAGLSDPGYI 150

  Fly   165 CGVDKTEDDCDDLFSYVPLVLIFLSQFVLGVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALRM 229
            || ::|..:       :..:|:..:|.:||||.|....||.:|:||:.::.::.|.:.:..:..:
Zfish   151 CG-NRTNTN-------MMYLLLIGAQMLLGVGATPLQPLGVSYIDDHVRREDSSLYIGILFSTLV 207

  Fly   230 IGPVVGFFFGFISLNTFID----PTKTPLIDSKDPRWLGAWWLGWVILGTLMCLFSGLIGLFPKQ 290
            .||..||..|.:....::|    .|.|..|...||||:||||.|::|.|..:.:.|..:..||:.
Zfish   208 FGPACGFILGSLCTKVYVDAVFIDTTTLDITPDDPRWIGAWWGGFIICGLFLFVSSFFMFGFPQS 272

  Fly   291 LPK----VNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADLPKLKDF 351
            |.:    .......:.||..|.|..|.:|..::|.:|:..:....|..|
Zfish   273 LNEPGEGPGGESEQAMLPAELVQEYEGVKTSDDLEISTGLTCCQHLQVI---------------- 321

  Fly   352 PRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGL 416
            |:....||.|.:....||:|...|...:||..||.||:|.||:....||..::|..:|....:|:
Zfish   322 PKVTKHLLSNPVFTCVILAACMEIAVVAGFAAFLGKYLEQQFNLSTSSANQLLGMTAIPCACLGI 386

  Fly   417 IGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCPN--------TFSMTQAGQLNLT-S 472
            ...|:::.|...|....:...:||..||....:|:.||.|..        .:.....|....| :
Zfish   387 FLGGLLVKKLDLSALGAIRLAMIVNIISTACYVSFLFLGCDTGPVAGVTVAYGNESLGSWERTEA 451

  Fly   473 NCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRGYNATSKLYEDCSCVVNDPAPKSAAQRLLNL 537
            .|...|:|...|.:|||.. ...|:.|||.|||...|.|.     |.|:.:...
Zfish   452 ACLSGCNCYKSSLSPVCGS-NGVTYLSACLAGCTRTNLTG-----CKCIAHSEG----------- 499

  Fly   538 LQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGIC-TKNCNWSFWAF 601
                    |.|.|                                    ||.| :..|..:|..|
Zfish   500 --------LGTAT------------------------------------PGKCPSPGCQQAFLTF 520

  Fly   602 SITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVW 666
            .......|..|:..:..:|::..|.|:.|.||:|.|:..:::.||..||.|:|||..||||||:|
Zfish   521 LAVVCACSMIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGIGIDSTCLLW 585

  Fly   667 TKTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLFDYLVWY--------YGRNLDIY 716
            :..|...|.|.|||...:||....::.:|.....:...:.|.        |.:|.:.|
Zfish   586 SSMCGIKGACMLYDNVTYRYLYVSIAIVLKSSAFILYAVTWQCLRHNYCKYIKNSEDY 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_001260417.1	OATP	36..684	CDD:281175	182/666 (27%)
		MFS	40..>280	CDD:119392	75/248 (30%)
		DUF4064	364..447	CDD:290013	25/82 (30%)
		KAZAL_SLC21	470..521	CDD:238650	18/51 (35%)
slco3a1b	XP_021333633.1	OATP	27..603	CDD:308646	182/666 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578755
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940