Protein Alignment Oatp33Ea and slco5a1a

DIOPT Version :9

• Sequence 1: NP_001260417.1
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_001340277.1
• Gene: slco5a1a / 570033
• ZFINID: ZDB-GENE-090316-1
• Length: 549
• Species: Danio rerio
• Alignment Length: 518
• Identity: 147/518 - (28%)
• Similarity: 233/518 - (44%)
• Gaps: 97/518 - (18%)

  Fly   221 LAVAMALRMIGPVVGFFFGFISLNTFIDPTKTPLIDSKDPRWLGAWWLGWVILGTLMCLFSGLIG 285
            ||:...:..:||..|:..|.|.:..::||.....||..|||::|.||.|:::....|.|....:.
Zfish     9 LAIMYVMGALGPAAGYLLGGILIGFYVDPGTVVNIDQGDPRFVGNWWSGFLLCAVAMLLVIFPMF 73

  Fly   286 LFPKQLP----------KVNASRTNSHLPLALRQTKEELKREENLSLSSR--FSSNAALDTIGAA 338
            .|||:||          |..|...:|         .:|:.:|::.::||.  |..|
Zfish    74 SFPKKLPPRQKKSKRGVKKGAGDVSS---------DDEMMKEKSQAVSSSMGFGKN--------- 120

  Fly   339 AGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATII 403
                     :||.|:|.:|:|.|...:|..||........:.|:||:.|::|.||...|.||:|.
Zfish   121 ---------IKDLPKAAVRILSNVTFLFVSLSYTAECAIVTAFITFIPKFIESQFGVPASSASIY 176

  Fly   404 VGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISI---------------LGQISYAF 453
            .|.|.:....||:...|.::.|.|....:.....:|..|:|:               ||.|:..:
Zfish   177 TGLIIVPSAGVGIFLGGYIIKKLKLGAREAAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPY 241

  Fly   454 LYCPNTFSMTQAGQLNLTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRGY-NATSKL--Y 515
            ...| |.:::..   |||.:||:||.|:...|.|||.. ...|:|:.|.|||... |.||.:  |
Zfish   242 TTGP-TLTLSHR---NLTGSCNVNCGCKIHEYAPVCGS-DGITYFNPCLAGCSNIANHTSGIRNY 301

  Fly   516 EDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRST 580
            .||:||        .:::::     ||              ||       |:.:.||:.......
Zfish   302 SDCACV--------QSRQVI-----TP--------------SG-------GNHELQLVIVKTYLN 332

  Fly   581 SDSVIRPGICTKNCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISL 645
            .:.....|.|.:.|. :...|.|...||:...:..:...::|..|:|..||:.||.|:..:::..
Zfish   333 ENGFALAGKCERTCG-TLITFLIFLFIVTLITACAQPSVIIVTLRSVDEEDRPFALGMQFVLLRT 396

  Fly   646 LALIPGPIIFGRLIDSTCLVWTKTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLFDYLVWY 708
            ||.||.||.||.:||:||::|.:.|..:|:|..||.|..|:....|:..|.|:|.||.:|.||
Zfish   397 LAYIPTPIYFGAVIDTTCMLWQQDCGFHGSCWEYDVTSLRFVYFGLAASLKFLGFLFIFLTWY 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_001260417.1	OATP	36..684	CDD:281175	137/492 (28%)
		MFS	40..>280	CDD:119392	19/58 (33%)
		DUF4064	364..447	CDD:290013	24/97 (25%)
		KAZAL_SLC21	470..521	CDD:238650	23/53 (43%)
slco5a1a	NP_001340277.1	OATP	<9..435	CDD:308646	137/492 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810