Protein Alignment Oatp33Ea and LOC556735

DIOPT Version :10

• Sequence 1: NP_609568.3
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_684701.3
• Gene: LOC556735 / 556735
• -ID: -
• Length: 859
• Species: Danio rerio
• Alignment Length: 735
• Identity: 212/735 - (28%)
• Similarity: 344/735 - (46%)
• Gaps: 138/735 - (18%)

  Fly    50 MSYMYFIVTL----------TTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRNRPRWI 104
            |.|:.||.:|          ||:|||:.:.|..:|:::|..:|..:::.:.:||.||:..||||:
Zfish   148 MCYLTFIQSLMVSGYLSSVITTIEKRYSLRSSESGLLVSCFDIGSLLVVVFISYFGGRGQRPRWL 212

  Fly   105 AWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSL------LNGTTGSDHSFQNISSVKTER 163
            |.|.||..:...:..||||| ...:::    ||...|:      |||....|  ..::||
Zfish   213 AVGGVFIAVGAALFSLPHFI-SPPYQI----KEVNSSMGNEGLCLNGNRSRD--ALDVSS----- 265

  Fly   164 LCGVDKTEDDCDDLFSYVPLVLIFLSQFVLGVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALR 228
             |..|:..:|     ..:.:.|...:|.::|:|:|..|:||.||||||.||.|..|.||:...:.
Zfish   266 -CPRDQEGND-----HSIYVALFVCAQVLVGMGSTPIYTLGPTYLDDNVKKENASLYLAIMYVMG 324

  Fly   229 MIGPVVGFFFGFISLNTFIDPTKTPLIDSKDPRWLGAWWLGWVILGTLMCLFSGLIGL-----FP 288
            .:||..|:..|.:.:..::||.....|:..|||::|.||.|:     |:|.|:.|:.:     ||
Zfish   325 ALGPAAGYLLGGVLIGFYVDPKTIVNIEQSDPRFVGNWWSGF-----LLCAFAMLLVIFPMFTFP 384

  Fly   289 KQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADLPKLKDFPR 353
            |:||..:..:...|...:.....:::.:|:         ||:...|:.::.|...|   :||.|:
Zfish   385 KKLPPRHKKKKKKHAADSASNDDDDVLKEK---------SNSKGQTVASSMGFGRD---IKDLPK 437

  Fly   354 ALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGLIG 418
            |.:|:|.|...:|..||........:.|:||:.|::|.||...|.:|:|..|.|.:....||::.
Zfish   438 AAIRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVL 502

  Fly   419 SGMVLSKKKPSVSKVLMWNVIVGGISI---------------LGQISYAFLYCPNTFSMTQAGQL 468
            .|.::.|.|....:.....:|..|:|:               ||.|:..:...| |.::|..
Zfish   503 GGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGP-TLTLTHR--- 563

  Fly   469 NLTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCR--GYNATS-KLYEDCSC-----VVNDP 525
            |||..||:||.|....|.|||.. ...|:|:.|.|||.  |.::|. :.|.||:|     |:..|
Zfish   564 NLTGGCNVNCGCRINEYAPVCGS-DGITYFNPCLAGCSTVGNDSTGIRNYTDCACVQSRQVITPP 627

  Fly   526 APKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGIC 590
            ......|..|.:::          ||          |::||                 ....|.|
Zfish   628 TSGQGNQLQLVIVK----------TY----------LNENG-----------------FALSGKC 655

  Fly   591 TKNCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIF 655
            .:.|| :...|.|...||:...:..:...::|..|:|..:::.||.|:..:::..||.||.||.|
Zfish   656 DRTCN-TLIPFLIFLFIVTLITACAQPSAIIVTLRSVDEQERPFALGMQFVLLRTLAYIPTPIYF 719

  Fly   656 GRLIDSTCLVWTKTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLFDYLVWY---YGRNLDIYG 717
            |.:||:||::|.:.|..:|:|..||.|.||:....|:..|.|:|.:|.:|.||   |
Zfish   720 GAVIDTTCMLWQQDCGIHGSCWEYDVTSFRFVYFGLAASLKFVGFIFIFLTWYSIKY-------- 776

  Fly   718 DKEAKEEERANRKDQPITPL 737
                 :|:|..|..|.:.||
Zfish   777 -----KEDRLKRWQQHLPPL 791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_609568.3	OATP	36..684	CDD:460821	195/677 (29%)
LOC556735	XP_684701.3	MFS_SLCO5_OATP5	142..689	CDD:340962	171/618 (28%)