Protein Alignment Oatp33Ea and Slco1a7

DIOPT Version :10

• Sequence 1: NP_609568.3
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_001365611.1
• Gene: Slco1a7 / 435927
• MGIID: 3643685
• Length: 670
• Species: Mus musculus
• Alignment Length: 714
• Identity: 167/714 - (23%)
• Similarity: 280/714 - (39%)
• Gaps: 136/714 - (19%)

  Fly    59 LTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHF 123
            |..:|::|.:.:.|.|:|.....:..:::.:.:||.|.:.:||..|..|.:|.||.|:|:.||||
Mouse    44 LLQIERQFGLLTSTVGLITGSFSMGMLLVIIPVSYFGTKLHRPIMIGVGCMFMGLGCFIISLPHF 108

  Fly   124 IYGAGHEVLQFTKEYQDSLLNGTTGSDHSFQNISSVKTERLCGVDKTED--DCDDLFSYVPLVLI 186
            :.|        ..||:.::...:..|.:||..:.:    |...:..|:|  :|......:..:.:
Mouse   109 LMG--------RYEYETTISPTSNLSSNSFLCMEN----RSLTLKPTQDTTECGREIKSLMWIYV 161

  Fly   187 FLSQFVLGVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDP-- 249
            .:...:.|:|.|....||.:|::|..|..|:||.:.:......|...:|:..|....|.::|.
Mouse   162 LVGNIIRGMGETAIMPLGISYIEDFAKSENSPLYIGILEIGITISYWIGYSLGSFCANIYVDTDS 226

  Fly   250 --TKTPLIDSKDPRWLGAWWLGWVILGTLMCLFSGLIGLFPKQLPKV----NASRTNSHLPLALR 308
              |....|...|.||:||||:|:::...:..|.|.....|||.|||.    |...|.:
Mouse   227 GNTDDLTITPTDTRWVGAWWIGFLVCAGVNFLTSIPFFFFPKTLPKEGLQDNGDGTEN------- 284

  Fly   309 QTKEELKREENLSLSSRFSSNAALDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVF 373
             .|||..||:....:.|.                     :|||...:..|..|.:.:..:|.:|.
Mouse   285 -AKEEKHREKAKKENQRI---------------------IKDFFPLMKNLSCNPIYMLYLLISVL 327

  Fly   374 YILGASGFMTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNV 438
            ........::::.||:|.|:.|.:.....|:|...:..:.:|.:..|:::.|.|.:..|..   .
Mouse   328 QFNTFVSMVSYVPKYLEQQYGKSSADVLFIMGIYMLPPICLGYLLGGLIMKKFKITAKKAA---Y 389

  Fly   439 IVGGISILGQISYAFLYCPNTFSMTQAG--------------QLNLTSNCNMNCSCEGISYTPVC 489
            |...:|:...:.....|..|..|...||              ...:.::||..|||...::.|||
Mouse   390 IAFCLSLTDYLLSLSNYMTNCDSFQVAGLTASYEGVQHPLHVDHEVLADCNTRCSCLTNTWDPVC 454

  Fly   490 HEPTDTTFFSACHAGCRGY--NATSKLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYF 552
            .. ....:.|||.|||...  |..:.::::|||:
Mouse   455 GN-NGLAYMSACLAGCEKSVGNGINMVFQNCSCI------------------------------- 487

  Fly   553 DEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTK--NCNWSFWAFSITSMIVSWFGSSG 615
                                     ||:.:|....|:|.|  :|:.....|.|...:..:..|..
Mouse   488 -------------------------RSSGNSSAVLGLCNKGPDCDNMLKYFIIIFSVKMFIFSLS 527

  Fly   616 RVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVW-TKTCNGNGNCQLY 679
            .:...:|..|.:..|:||...||......:.|.||.||.||.|||..||.| |..|.....|::|
Mouse   528 SIPGYMVLLRCMKPEEKSLGVGLHTFCTKIFAGIPAPIYFGALIDRACLHWGTLKCGEKAACRIY 592

  Fly   680 DQTRFRYSLNFLSCLLTFMGLLFDYLVWYYGRNLDIYGDKEAKEEERANRKDQPITPLLAKKSE 743
            |...|||....|...||....|....:....|...:..|.::.:.|.|.      |.|:.|:::
Mouse   593 DINSFRYLFFGLPAALTGSSYLPAVFLLRLMRTFQLPEDTDSPDTELAE------TKLIEKEND 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_609568.3	OATP	36..684	CDD:460821	153/653 (23%)
Slco1a7	NP_001365611.1	oat	1..624	CDD:273279	160/680 (24%)