Protein Alignment Oatp33Ea and slco1f1

DIOPT Version :10

• Sequence 1: NP_609568.3
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_073801947.1
• Gene: slco1f1 / 405853
• ZFINID: ZDB-GENE-040426-2192
• Length: 683
• Species: Danio rerio
• Alignment Length: 710
• Identity: 183/710 - (25%)
• Similarity: 301/710 - (42%)
• Gaps: 151/710 - (21%)

  Fly    35 KMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRN 99
            |:|:.........::|:..|...|:|.:||||:|.|.|.|.|....|:..:::..::||:|.:.:
Zfish    73 KIFICALAFCYFSKSMTASYTKSTITQIEKRFEITSSTVGFIDGSFEMGNMLVITLVSYVGAKFH 137

  Fly   100 RPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSLLNGTTGSDHSFQNISSVKTERL 164
            ||:.|..|::..|:...::..|||:.|          .|:.......|....:|..||:..::..
Zfish   138 RPKIIGAGVLLMGIGTLLMASPHFLMG----------RYKYGTAATHTNDAGNFTVISTCSSDSQ 192

  Fly   165 CGVDKTEDDCD--DLFSYVPLVLIFLSQFVLGVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMAL 227
            ..:.:...:|.  :..|.:..|::.|...:.|:|......||.:::||..:..|:...:.....|
Zfish   193 ETLQQPYSECQIIEAESSLLWVVVLLGNAMRGIGEASIVPLGMSFIDDYARPENSAFYIGCLNTL 257

  Fly   228 RMIGPVVGFFFGFISLNTFID--------PTKTPLIDSKDPRWLGAWWLGWVILGTLMCLFSGLI 284
            |.|||:.||..|.:..|.::|        .|.||    :|.||:||||||:|:.|.|..|.:...
Zfish   258 RGIGPIFGFILGSLCANLYVDFDLVNQESVTITP----QDSRWVGAWWLGFVVSGLLTLLAAFPF 318

  Fly   285 GLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADLPKLK 349
            ...|:.||:      ||       || .||...     |.:..:..:|..|            :|
Zfish   319 WFLPRALPE------NS-------QT-SELDHP-----SEQHKTTPSLTEI------------IK 352

  Fly   350 DFPRALMRLLRNKLLIFNILSAVFYILGASGF---MTFLTKYMEVQFHKDAQSATIIVGPISIMG 411
            ||.....|||.||:.   ||...:.|:..:.|   .|:..||:|.||.:.|..|..::|...|..
Zfish   353 DFAPTFKRLLTNKIY---ILYLAYSIVAFNDFAIVATYTPKYLEQQFGQSASKANFLIGVTCIPA 414

  Fly   412 MVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCPNTFSMTQAGQL-------- 468
            :.:|:..||:::.:.|..:......|:..|...:|..:.:..|.|.|   :..||..
Zfish   415 VALGIFLSGLMMKRFKWGLLASARVNLFTGVTMLLLAVPFFALSCEN---LDVAGVTVPYQGSTE 476

  Fly   469 ------NLTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCR-----GYNATSKLYEDCSCVV 522
                  ::..:||.:|.|..:.:.|||.| ...|:.|.|||||.     |:|   |.:.||.|:.
Zfish   477 VQGVISDVLPSCNADCGCPDLQWDPVCGE-NGVTYISPCHAGCNSTQGAGWN---KTFHDCRCIQ 537

  Fly   523 NDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRP 587
            :                                 .|:.:                 ..|.:|:
Zfish   538 S---------------------------------WGLSV-----------------GNSSAVL-- 550

  Fly   588 GICTK--NCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIP 650
            |.|::  |||...:.|.....:|.:..|.|.|..:..:.|.|..|.|:.:.|:.|:.|.:|..||
Zfish   551 GQCSRDPNCNQMIYVFLGVQSLVLFVYSLGAVPFLTFSMRIVDPEMKALSVGVLLLSIRVLGGIP 615

  Fly   651 GPIIFGRLIDSTCLVW--TKTCNGNGNCQLYDQTRFRY-------SLNFLSCLLTFMGLL 701
            .||.||.|||:|||.|  .|:| |.|.|::||...||:       .|..|:|.:.::..:
Zfish   616 APIYFGGLIDTTCLKWGQRKSC-GRGACRIYDNETFRFLFQGMTIGLRVLACSVLWIATI 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_609568.3	OATP	36..684	CDD:460821	177/683 (26%)
slco1f1	XP_073801947.1	None