Protein Alignment Oatp33Ea and Oatp74D

DIOPT Version :9

• Sequence 1: NP_001260417.1
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_001163460.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Alignment Length: 757
• Identity: 223/757 - (29%)
• Similarity: 341/757 - (45%)
• Gaps: 138/757 - (18%)

  Fly    18 CGMANWHPPWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEI 82
            ||:....|.|.:::|:|.:||.|:.|...:|.|...||:..:||:||.|:|.|:||||:||.:|:
  Fly   157 CGLFGCRPRWARRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEM 221

  Fly    83 SQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGA----GHEVLQFTKEYQDSLL 143
            .||..:::|:|..|:.:||||||.|:|...::.:...|||||:|.    ...:||.|   |.|..
  Fly   222 GQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSVILQQT---QVSPP 283

  Fly   144 NGTTGSDHSFQNISSVKTERLC--GVDKTE--DDCDD----------LFSYVPLVLIFLSQFVLG 194
            |.:. |.|.....|......||  |.::|.  .:|::          ..:.:.|.:.|.|....|
  Fly   284 NNSF-SSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSG 347

  Fly   195 VGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDPTKTPLIDSKD 259
            :|.|...:||..|:|||.....:|:.:||.:.:|::||..||.||......::: ...|..|:.|
  Fly   348 IGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVN-FSNPGFDATD 411

  Fly   260 PRWLGAWWLGWVILGTLMCLFSGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSS 324
            |||:||||||.|.:|:||.|.|..:..|||||.........:..|.|..:.:|:
  Fly   412 PRWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPGQTATPAAPVEPEEK----------- 465

  Fly   325 RFSSNAALDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYM 389
                                 |||||||:.:.|.|.|.:|:|...|.||::|..:|..|||.||:
  Fly   466 ---------------------PKLKDFPKTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYL 509

  Fly   390 EVQFHKDAQSATIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFL 454
            |.||......|.:|.....|:.|.:|::.||:.:.|:||:...|..|......:...|.|...|:
  Fly   510 ETQFRLATYDANMIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMFI 574

  Fly   455 YCP-NTFSMTQAGQLNL------TSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRGY---- 508
            .|. |.|:..:....|.      |.:..:||:|:..::.|:|.:  ...:.|||||||...
  Fly   575 GCSMNDFAGYKPSDGNSPALIEPTCSAALNCTCDKENFAPICAD--GKMYISACHAGCSSSSLRP 637

  Fly   509 --NATSKLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQ 571
              |.|  ||.||:|:.:.|...:
  Fly   638 SDNRT--LYSDCACIPDAPEAVN------------------------------------------ 658

  Fly   572 LLSRTRRSTSDSVIRPGICTKNCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQ 636
                            |.|..||. :|..|.:...|..:..|:..||::|:..|....:||:.|.
  Fly   659 ----------------GYCDNNCK-NFIYFILIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAM 706

  Fly   637 GLALMMISLLALIPGPIIFGRLIDSTCLVWTKTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLL 701
            |:....|.|...:|.|||:|.::||.||:|...|..:|.|.|||...||.....::..:.|:..|
  Fly   707 GVIQSAIGLFGNVPCPIIYGAVVDSACLIWKSVCGKHGACSLYDADTFRQYFLGITAGIMFLAFL 771

  Fly   702 FDYLVWYYGRNLDIYGDKEAKEEERAN-------RKDQPITP 736
            .|.:||.....:||..:...:....:|       ...|||||
  Fly   772 MDLVVWRKAHRIDIAPEDPQEGGPASNGRTLEVSESKQPITP 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_001260417.1	OATP	36..684	CDD:281175	202/678 (30%)
		MFS	40..>280	CDD:119392	91/257 (35%)
		DUF4064	364..447	CDD:290013	27/82 (33%)
		KAZAL_SLC21	470..521	CDD:238650	19/62 (31%)
Oatp74D	NP_001163460.1	OATP	175..754	CDD:335235	202/678 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446201
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4773
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3798
	7	6.850