Protein Alignment Oatp33Ea and Oatp58Dc

DIOPT Version :10

• Sequence 1: NP_609568.3
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_611659.2
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Alignment Length: 741
• Identity: 273/741 - (36%)
• Similarity: 422/741 - (56%)
• Gaps: 78/741 - (10%)

  Fly    18 CGMANWHPPWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEI 82
            ||...:...:.|::|....::.:||::|.|.:|:|.||..|:||:||||||||:.||||..||:|
  Fly    94 CGFWIFKGTFYQRFANQTAYVLLYGIVGCIFSMTYAYFNGTITTIEKRFKIPSKNTGIISVGNDI 158

  Fly    83 SQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSLLNGTT 147
            ||.::|.:|:|..|:.:|||||.:|::.....|.:...|||:||.|.:.|..|.|:     .|..
  Fly   159 SQTLVSAVLAYYAGKGHRPRWIGFGLLTIVFFCILTTAPHFLYGPGEDALALTSEF-----GGMP 218

  Fly   148 GSDHSFQNISSVKTERLCGVDKTEDDCD-DLFSYVPLVLIFLSQFVLGVGNTLYYSLGQTYLDDN 211
            ..:.:.:.|...:::.||.::....:|: ...::.|.:|:|::||:.|:|.:|||:||.:|:|||
  Fly   219 DENATMEAIEEQRSKTLCRLNGGGAECEVGEGNFAPQLLLFVAQFISGIGGSLYYTLGVSYMDDN 283

  Fly   212 TKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDPTKTPLIDSKDPRWLGAWWLGWVILGTL 276
            |||:.||.:|:::..|||:||.:|:......|..:|.|...|:|::|||||||||||||:::|.|
  Fly   284 TKKSKTPALLSLSYFLRMLGPAIGYALASFCLRLYIAPQMHPVINNKDPRWLGAWWLGWLVMGGL 348

  Fly   277 MCLFSGL-IGLFPKQLPKVNASRTNSHLPLALRQTKEELKRE-ENLSLSS----RFSSNAALDTI 335
            :. |||: :.:|||:||:.          :|.|:.:|..:|| |.||:.|    |.::.....|.
  Fly   349 LS-FSGVFLSMFPKELPRA----------VARRKVEENRRREKERLSVKSTEKERLTAELDQKTT 402

  Fly   336 GAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSA 400
            ..|..:..|:  ||.|    .||:.||..:.|.||::||::|.:.:..|..||:|||:.:.|.::
  Fly   403 AEAKASFQDM--LKTF----RRLITNKTYMCNTLSSIFYLVGYTPYWIFTPKYIEVQYRQSAATS 461

  Fly   401 TIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCP-------- 457
            :::.|.:::....||::.||.::|:.||....:..||||||.:::.|.::|||:.||
  Fly   462 SMVTGTVALAFSAVGVLLSGFIISRYKPRARYMAAWNVIVGFLTVAGILAYAFIGCPGNESSVIV 526

  Fly   458 NTFSMTQAGQLNLTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRGYNATS---KLYEDCS 519
            |....:.||.   |:.||..|||:.:.|:|||.| .:.|:.|||||||:.....|   |::.|||
  Fly   527 NIHDSSLAGN---TTTCNSACSCDYVRYSPVCGE-NNMTYISACHAGCKKLLVNSEGKKIFYDCS 587

  Fly   520 CVVNDPAPKSAAQ--RLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSD 582
            |:.:|.|..|.:|  ||               |.||  ||. ..:..|.....||     .:.::
  Fly   588 CIPSDDAGNSTSQFKRL---------------TSFD--LSN-DEVSQNTSVHSQL-----EALAN 629

  Fly   583 SVIRPGICTKNCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLA 647
            ....||.|..||...|.||......:.:.|:|||..|.||:.|.|..:||:.|.|..:.:.|:||
  Fly   630 GQAMPGACPVNCWTQFVAFLAVMCCLKFVGASGRASNFLVSVRCVPEKDKTAAMGFGMTLCSMLA 694

  Fly   648 LIPGPIIFGRLIDSTCLVWTKTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLFDYLVWYYGRN 712
            .||.||.||.:.|..||||.|||...|||.|||....||:|||.:.:...:|.:||..||||.::
  Fly   695 FIPSPIFFGWVFDRVCLVWGKTCTNKGNCWLYDPLSMRYTLNFTAAVFIAIGAIFDLGVWYYAKD 759

  Fly   713 LDIYGDKEAKE--------EERANRK 730
            |.|: |::.||        ||.||.:
  Fly   760 LKIF-DEDVKEVEMKIVQHEEEANNE 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_609568.3	OATP	36..684	CDD:460821	248/667 (37%)
Oatp58Dc	NP_611659.2	OATP	113..731	CDD:460821	248/666 (37%)