Protein Alignment Oatp33Ea and Oatp26F

DIOPT Version :10

• Sequence 1: NP_609568.3
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Alignment Length: 744
• Identity: 197/744 - (26%)
• Similarity: 325/744 - (43%)
• Gaps: 169/744 - (22%)

  Fly    19 GMANWHPPWLQKYATTK--MFMGVYGLLGTIQAMSYMYFI-VTLTTLEKRFKIPSQTTGIILSGN 80
            |...|:|.|||::.|.|  :|...:|  |.:|.:.....| |:::|:|:||.:.|:..|::.||.
  Fly    49 GWCGWNPAWLQRFCTAKWALFWLCWG--GALQGLIVNGLINVSISTIERRFGLRSRQMGLVASGY 111

  Fly    81 EISQIMLSLILSYIGGQR--NRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSLL 143
            :::.....:.::|.||:|  ::||:||.|::..|:...:.:||:|:.|          .|:.::.
  Fly   112 DLASFACLVPVTYYGGRRGASKPRFIAIGLIVMGMGSLVFLLPNFLVG----------NYRATIA 166

  Fly   144 NG----TTGSDHSFQNISSVKTERLCGVDKTEDDCDDLFSYVPLVLIFL-SQFVLGVGNTLYYSL 203
            ..    |||...   |.:|.::...|.::...:...:..::.  |.:|| :|.:.|.|.:..::|
  Fly   167 EANVCETTGLPF---NSNSSQSMTACELNAMGEGQSENLTWT--VWLFLAAQLLHGAGASPLFTL 226

  Fly   204 GQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTF-----IDPTKTPLI-DSKDPRW 262
            |.||:|:|..|..:.:.|.:...:..:||.:|:.||...|..:     :||.:..|. |||  .|
  Fly   227 GVTYIDENVSKKMSSVYLGIYYTMATVGPAIGYVFGGQLLLIYTDWMTVDPVQLSLTSDSK--VW 289

  Fly   263 LGAWWLGWVILGTLMCLFSGLIGL----FPKQLPKVNASRTNSHLPLALRQTKEELKR--EENLS 321
            :||||||: |....|||   ||.|    :||.||...               |.:|:|  |.:.:
  Fly   290 IGAWWLGF-IFAAAMCL---LIALPIFGYPKLLPGAE---------------KLQLERVSEAHAT 335

  Fly   322 LS-SRFSSNAALDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFL 385
            :| :..|||.                 ::..|||::.||.|....|..|:.....|..:||..||
  Fly   336 ISEADDSSNV-----------------VRGLPRAVLSLLANPTFFFLNLAGATEGLVIAGFAAFL 383

  Fly   386 TKYMEVQFHKDAQSATIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGI------- 443
            .|.:|.||......:.:::|.|::.....|....|.::.|          ||:...||
  Fly   384 PKQIENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKK----------WNLACRGIIKMCLLA 438

  Fly   444 -SILGQISYAFLY-CPN-TFSMTQAG--------QLNLTSNCNMNCSCEGISYTPVCHEPTDTTF 497
             ::....:..||. ||| .|:....|        ...|.::||.||.|...:|.|:| ......:
  Fly   439 TTVAALFTICFLVSCPNPKFAGVTTGYKMQPSSDSPALVASCNSNCGCSRTNYDPIC-GVDGVMY 502

  Fly   498 FSACHAGC-RGYNATS-KLYEDCSCV-----VNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEY 555
            :|.|:||| :..:|.| |.|.:|||:     |:|..|.|.|        |...|:. |....|..
  Fly   503 YSPCYAGCVQEEHANSLKRYHNCSCIEQVGFVDDGNPSSEA--------PHFRPDA-TNRKCDST 558

  Fly   556 LSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTKNCNWSFWAFSITSMIVSWFGSSGRVGNV 620
            ...:||                                    |.|.....|:.::..:...:...
  Fly   559 CQTLPL------------------------------------FVALCFILMVFTFLATMPALSAT 587

  Fly   621 LVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVWTKTC--NGNGNCQLYDQTR 683
            |   |.|..:.:|||.||..:.:.||..||.|:|||.|||.:|::|.::|  :..|.|.:||...
  Fly   588 L---RCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALIDESCILWQESCDKDAGGACLVYDNFY 649

  Fly   684 F-RYSLNFLSCLLTFMG--LLFDYLVWYY 709
            . ||.  :|..|:..:|  :.|....|:|
  Fly   650 ISRYM--WLLALICKLGSVVFFACAWWFY 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_609568.3	OATP	36..684	CDD:460821	181/695 (26%)
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	157/638 (25%)