Protein Alignment Oatp33Ea and F21G4.1

DIOPT Version :10

• Sequence 1: NP_609568.3
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_509659.3
• Gene: F21G4.1 / 181203
• WormBaseID: WBGene00009023
• Length: 640
• Species: Caenorhabditis elegans
• Alignment Length: 760
• Identity: 185/760 - (24%)
• Similarity: 310/760 - (40%)
• Gaps: 185/760 - (24%)

  Fly    29 QKYA-TTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILS 92
            :||. :..:|:.:..|:..:|.....|.:..||||||||...|:.:|.:||..:|...|..|::.
 Worm    10 KKYKFSINIFVLLMVLVIAVQGTYLGYVVGMLTTLEKRFGFSSEKSGWLLSLYDIGHTMAILLIG 74

  Fly    93 YIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGAG----HEVLQFTKEYQDSLLNGTTGSDHSF 153
            |||...:.||....|::...||.::|.||...||..    .:::|..:.|...:...|.|.
 Worm    75 YIGSHYHLPRITGIGVILSSLSMFMLALPVLFYGTADYTQEQLMQKKEAYSVEMSCDTNGR---- 135

  Fly   154 QNISSVKTERLCGVDKTEDDC-------DDLFSYVPLVLIFLSQFVLGVGNTLYYSLGQTYLDDN 211
            :.|||           ..:||       .:.|     :::...|...|:....:.::...|:|.|
 Worm   136 REISS-----------QGEDCWREHHEHTNAF-----IILAFGQLFAGIFAAPFNTIAYVYIDSN 184

  Fly   212 TK-KTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDPTKTPL------IDSKDPRWLGAWWLG 269
            .| |..:|.:|.:..::...||.:||.     |::.::...|.|      |.:.|..|:||||||
 Worm   185 VKQKRESPFLLGLLTSMYAFGPALGFM-----LSSILNGVYTSLGDAPDHIGTHDEHWIGAWWLG 244

  Fly   270 WVILGTLMCLFSGLIGLFPKQLPKVNASRTNSH---LPLALRQTKEELKREENLSLSSRFSSNAA 331
            :::.|:...:.:.....||         ||..|   ..|.|..::.::..|:.|:    |..|..
 Worm   245 FLVCGSAYLILAVPFFFFP---------RTYKHPDSFHLMLEHSRPQVSPEDRLT----FKENIT 296

  Fly   332 LDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVF--YILGASGFMTFLTKYMEVQFH 394
            |              .|::||..|.:|:.||:.|..:::.:|  |::|  |:.|:|.|::|.|:.
 Worm   297 L--------------FLREFPMVLKKLITNKVYITMVIAWMFGSYLIG--GYQTYLPKFIETQYG 345

  Fly   395 KDAQSATIIVGPISIMGMVVGLIGSGMVLSKKK--PSVSKVLM---WNVIVGGISILGQISYAF- 453
            :.|..|.|..|.||:..:.|.....|.:||:..  |..|.:.:   |.||:        :||..
 Worm   346 RSASMADIYSGIISVGAIAVSTALGGWILSRYNIAPRSSIICLIGSWIVIL--------VSYIIG 402

  Fly   454 --LYC--PNTFSMTQAGQLN---------LTSNCNMNCSCE------GISYTPVCHEPTDTTFFS 499
              |.|  |....:|.....:         ....|...|:||      |:||       ....|:|
 Worm   403 MNLGCSQPKVEGLTYVDYASRWHFYHHREREQECLEYCNCETVLKFDGVSY-------NGQNFYS 460

  Fly   500 ACHAGCRGYNATSKLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDD 564
            .|||||..|:..|..:.:|.|...:...|       .|:.|      |...:| .||: |.|:
 Worm   461 PCHAGCTEYDIYSNTWSNCQCAYGNMVDK-------GLVHP------DCGIFF-AYLA-VMLI-- 508

  Fly   565 NGDFDDQLLSRTRRSTSDSVIRPGICTKNCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAH 629
             |.|...|.                           |.:|.|||               .|:|..
 Worm   509 -GLFIGNLF---------------------------FMVTMMIV---------------LRSVFD 530

  Fly   630 EDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVWTKTC-NGNGNCQLYDQTRFRYSLNFLSC 693
            |:|..|..||..:.:|...||.|:|:|..||..|::|.:.| |..|||.|||...|....:.::.
 Worm   531 EEKVIALSLASFITNLFGFIPAPVIYGFFIDLCCILWNRQCPNERGNCVLYDNDMFTKMFHGVNS 595

  Fly   694 LLTFMGLLFDYLVWYYGRNLDIYGD------KEAKEEERANRKDQ 732
            ......::|..:.::..:.:.:..:      .|::|.|..:.:::
 Worm   596 FFQVFAIIFAGICYWLSKTVKLPEEMPMVDFPESREREYRDEEEE 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_609568.3	OATP	36..684	CDD:460821	178/696 (26%)
F21G4.1	NP_509659.3	OATP	18..586	CDD:460821	178/696 (26%)