Protein Alignment Oatp33Ea and F47E1.4

DIOPT Version :10

• Sequence 1: NP_609568.3
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_509532.1
• Gene: F47E1.4 / 181146
• WormBaseID: WBGene00018568
• Length: 728
• Species: Caenorhabditis elegans
• Alignment Length: 817
• Identity: 191/817 - (23%)
• Similarity: 316/817 - (38%)
• Gaps: 215/817 - (26%)

  Fly    36 MFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRNR 100
            :|:.::.::..::::...|....|.::|::|::.|..:|:::|..|...|...:|:||.|.:.||
 Worm     6 IFIVLFVVVFFLESIGASYIYTALQSIERQFQMSSGISGLLVSATECGYIPCVVIMSYFGSKGNR 70

  Fly   101 PRWIAWGIVFCGLSCYILVLPHFIYGAGHE----------------------------------- 130
            .|||..|::...::..:|..|:|::....:
 Worm    71 SRWIGGGVLLMSITYLMLGTPNFLFPTRQQKTNGLNISESLRPTPSQLLPNSTLKDLLSYPLMED 135

  Fly   131 ---------VLQFTKE------------YQDSLLNGTTG---------------------SDHSF 153
                     :|..|.:            .|.|..|.|.|                     |.:|.
 Worm   136 QLPSSTYQFLLNLTDDKTPIEQTQTEPTEQGSNPNVTFGIDGYLMKGILIEADNLVKNNYSQNSI 200

  Fly   154 QNISSVKTERLCGVDKTEDD--------------CDDLFSYV-----------------PLVLIF 187
            :.:.|:...|  .|:::.||              |..|.:::                 |.::.|
 Worm   201 KQLLSMFIHR--RVNRSIDDIQKMKTKAVVPFTVCGKLTNFLRASIENSKCRAGSSNIWPFLVFF 263

  Fly   188 LSQFVLGVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDPTKT 252
            :|.|.||||.|:.::||...||||.||.:.|:......::|::||:.|:..|..| |.|....:.
 Worm   264 VSLFFLGVGRTIPWNLGIPLLDDNIKKKHLPMYFGAIASIRVLGPICGYLIGSFS-NQFYYTLQA 327

  Fly   253 PL-IDSKDPRWLGAWWLGWVILGTLMCLFSGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKR 316
            |. :...:..|:||||||::::|.|....|.|:..||:        ..||.|.|      .|::.
 Worm   328 PSGLTPVNQGWIGAWWLGFLLIGALSMFPSLLLFFFPQ--------GKNSTLQL------REIRE 378

  Fly   317 EENLSLSSRFSSNAALDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGF 381
            .:|                |.|:.:.....|:|:|..:...:|..|:....:|..|..|....|:
 Worm   379 NKN----------------GRASESKPIKMKIKEFVISCKSVLGTKIFTGCLLGRVCDIFAFKGY 427

  Fly   382 MTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISIL 446
            :.||.||:|.||..........:....:.|..:|:...|.:..|.:.:..:..:..:||..::|.
 Worm   428 VVFLPKYLETQFGIPQYLVHRYMSMFGVFGFGLGIALGGFITKKFRLTGRQTALLMMIVSVLNIT 492

  Fly   447 GQISYAFLYC---PNTFSM-TQAGQLNLTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRG 507
            ...|..|:.|   .|:..: ::....|.|:.||..||||.....||| ....|.:||.||||||
 Worm   493 VYSSKIFIGCNLIVNSIGLNSRELNYNFTNECNSQCSCENAHLYPVC-SADGTAYFSPCHAGCR- 555

  Fly   508 YNATS------KLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNG 566
             .||.      ..:..|.||
 Worm   556 -EATQFGSDPVIGFASCECV--------------------------------------------- 574

  Fly   567 DFDDQLLSRTRRSTSDSVIRPGICTKNCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHED 631
                          ...|:....|...|.:|...|..|.::.|:......|.::|:..|:|....
 Worm   575 --------------ESGVVSKSFCQNKCQFSSILFLATVLLGSFVAGVAVVPDMLILLRSVDVGS 625

  Fly   632 KSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVWTKTCNG-NGNCQLYDQTRFRYSLNFLSCLL 695
            :|.:.||..|.|||...:|..||:|.:||:.|.||.||||| ||:|.:||....|..::.|...:
 Worm   626 RSLSMGLQGMAISLFGTLPSSIIWGLVIDTACRVWDKTCNGANGSCSIYDSDHLRIWMHLLYVGV 690

  Fly   696 TFMGLLFDYLVWYYGRNLDIYGDKEAKEEERANRKDQ 732
            .|:.||.|..||....||.|..|..|...|..:..|:
 Worm   691 RFISLLSDIYVWKNAGNLKIMDDPVADNIEALSNPDK 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_609568.3	OATP	36..684	CDD:460821	176/767 (23%)
F47E1.4	NP_509532.1	oat	95..707	CDD:273279	161/706 (23%)