Protein Alignment Oatp33Ea and Slco3a1

DIOPT Version :10

• Sequence 1: NP_609568.3
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_803434.2
• Gene: Slco3a1 / 140915
• RGDID: 620227
• Length: 692
• Species: Rattus norvegicus
• Alignment Length: 688
• Identity: 186/688 - (27%)
• Similarity: 292/688 - (42%)
• Gaps: 130/688 - (18%)

  Fly    45 GTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRNRPRWIAWGIV 109
            ||:.|    |.:..|||||:||.:.|...|:|.|..||..:.|.|.:||.|.:.:|||.|..|.:
  Rat    54 GTVGA----YLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGI 114

  Fly   110 FCGLSCYILVLPHFI-----YGAGHEVLQFTKEYQDSLLNGTTGSDHSFQNISSVKTERLCGVDK 169
            ...|...:..||.|:     |.||.  :::..|.:|......:.||.              |.|
  Rat   115 VMALGALLSALPEFLTHQYKYEAGE--IRWGAEGRDVCATNGSSSDE--------------GPD- 162

  Fly   170 TEDDCDDLF------SYVPLVLIFLSQFVLGVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALR 228
                 .||.      :.:..:|:..:|.:||:|.|....||.:|:||:.::.::.|.:.:...:.
  Rat   163 -----PDLICRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTML 222

  Fly   229 MIGPVVGFFFGFISLNTFID----PTKTPLIDSKDPRWLGAWWLGWVILGTLMCLFSGLIGLFPK 289
            :.||..||..|......::|    .|....|...||||:||||.|:::.|.|:...|.|:..||:
  Rat   223 VFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQ 287

  Fly   290 QLPKVNASRTNSH---LPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADLPKLKDF 351
            .||..:.....|.   ||      :.|.:|.:        .||..|........:.:...:|:..
  Rat   288 SLPPHSEPGMESEQAMLP------EREYERPK--------PSNGVLRHPLEPDSSASCFQQLRVI 338

  Fly   352 PRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGL 416
            |:....||.|.:....:|:|...|...:||..||.||:|.||:....||..::|..:|....:|:
  Rat   339 PKVTKHLLSNPVFTCIVLAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGI 403

  Fly   417 IGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCPN----------TFSMTQAGQLNLT 471
            ...|:::.|...|....:...::|..:|....:|:.||.|..          ..:..:...|:..
  Rat   404 FLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVRYGNNSARGSPLDPY 468

  Fly   472 SNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRGYNATSKLYEDCSCVVNDPAPKSAAQRLLN 536
            |.||.||.|:..|:|||| .....|:.|||.|||...|.|.     |:|:...|
  Rat   469 SPCNNNCECQTDSFTPVC-GADGITYLSACFAGCNSTNLTG-----CACLTTVP----------- 516

  Fly   537 LLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGIC-TKNCNWSFWA 600
                   ||                                    ::.:.||.| :..|..:|..
  Rat   517 -------PE------------------------------------NATVVPGKCPSPGCQEAFLT 538

  Fly   601 FSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLV 665
            |.....:.|..|:..:..:|::..|.|:.|.||:|.|:..:::.||..||.|:|||..||||||.
  Rat   539 FLCVMCVCSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLF 603

  Fly   666 WTKTCNGNGNCQLYDQTRFRY-SLNFLSCLLTFMGLLF 702
            |:..|...|.|.|||...:|| .::....|.:|..:|:
  Rat   604 WSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILY 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_609568.3	OATP	36..684	CDD:460821	181/667 (27%)
Slco3a1	NP_803434.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		MFS_SLCO3_OATP3	39..563	CDD:340960	153/608 (25%)