Protein Alignment Oatp33Ea and LOC1277224

DIOPT Version :10

• Sequence 1: NP_609568.3
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_316669.4
• Gene: LOC1277224 / 1277224
• VectorBaseID: AGAMI1_000322
• Length: 772
• Species: Anopheles gambiae
• Alignment Length: 730
• Identity: 274/730 - (37%)
• Similarity: 417/730 - (57%)
• Gaps: 69/730 - (9%)

  Fly    18 CGMANWHPPWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEI 82
            ||...:..|.||::|..|:::.:||::|.|.:.:|.||..|:||||||:||||:.||||..||:|
Mosquito    96 CGFWMFQGPMLQRFANKKVYVFMYGVVGCIFSATYAYFNGTITTLEKRYKIPSKNTGIISVGNDI 160

  Fly    83 SQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSLLNGTT 147
            |.::||.||||..|:.:||||||:|::.....|::..|||.:||.|...|..|.||     ..|.
Mosquito   161 SALLLSAILSYYAGKGHRPRWIAFGLLMITAFCWLTALPHLLYGPGEAALSLTTEY-----GATY 220

  Fly   148 GSDHSFQNISSVKTERLCGVDKTED-DCD-DLFSYVPLVLIFLSQFVLGVGNTLYYSLGQTYLDD 210
            .::.:.:.:.:.|.:.||..:.|.. :|: :..:..|.:::|::||:.|:|::|||:||.:|:||
Mosquito   221 DANQTAEVMEAQKAKILCRTNATRGAECEREEGTLAPQIVLFIAQFISGIGSSLYYTLGVSYMDD 285

  Fly   211 NTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDPTKTPLIDSKDPRWLGAWWLGWVILGT 275
            |.||:.||.:::|:..|||:||.:|:......|..:|.|:.||.|.:.|||||||||:||:|||.
Mosquito   286 NIKKSKTPALVSVSYFLRMLGPAIGYTLASYFLKLYISPSMTPTISNTDPRWLGAWWMGWLILGA 350

  Fly   276 LMCLFSGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAG 340
            ::..|:..:.:||||||:.           |.|:...:.||...:.||.             |:.
Mosquito   351 VLAFFAIFMAMFPKQLPRA-----------AARKRIAQEKRRLGMQLSD-------------ASK 391

  Fly   341 ANADLP-KLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIV 404
            ...:|| ..||..:...||||||:|:.|.:::|||..|...:..|..||:|.|:.:.|.:::::.
Mosquito   392 REDELPASFKDMLKTFKRLLRNKILMLNNIASVFYFFGYMPYWIFTPKYIETQYKQSASTSSLVT 456

  Fly   405 GPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYC---PNTFSMTQAG 466
            |.:::....:|::.||:|:||.||....:..||||||.:|::|.|:||||.|   .|:..:....
Mosquito   457 GTVALCFSAIGVLLSGLVISKFKPRARYMAAWNVIVGLLSVMGMIAYAFLGCSASENSVIVNIPS 521

  Fly   467 QLNLTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRGYN--ATSKLYEDCSC---VVNDPA 526
            |.:||..||..|.|:.:.|:|:|.| ...|:.|||||||:..|  ...|:|.:|||   |||..:
Mosquito   522 QTDLTPTCNSACQCDYVKYSPICGE-DGNTYISACHAGCKRQNQYGDLKIYGECSCITPVVNYTS 585

  Fly   527 PKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICT 591
            |      |.|.|.....   .|||      |.....|:|           ..|...|.| .|.|.
Mosquito   586 P------LYNQLLTGGN---HTTT------STAAARDEN-----------MFSLGGSAI-AGPCP 623

  Fly   592 KNCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFG 656
            .||...|..|.:....:.:.|::||..|.||:.|.|..:||:.:.|..:|::||::.||.||.||
Mosquito   624 LNCQKEFITFLVVMCFLKFSGATGRASNFLVSVRCVDEKDKAVSMGFGMMVLSLMSFIPSPIFFG 688

  Fly   657 RLIDSTCLVWTKTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLFDYLVWYYGRNLDIYGDK-E 720
            .::|.|||||.|||.|.|||.|||....||.|||::.....:|.|||..||||.::|.|:.|: :
Mosquito   689 LVLDKTCLVWGKTCTGKGNCWLYDGETLRYLLNFIAAAFVLVGTLFDCGVWYYVKDLKIFDDEVQ 753

  Fly   721 AKEEERANRKDQPIT 735
            .||...|:::::.||
Mosquito   754 DKEIALADKEEEAIT 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_609568.3	OATP	36..684	CDD:460821	246/658 (37%)
LOC1277224	XP_316669.4	OATP	114..716	CDD:460821	246/658 (37%)