Protein Alignment Oatp33Ea and LOC1277223

DIOPT Version :10

• Sequence 1: NP_609568.3
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_001237849.3
• Gene: LOC1277223 / 1277223
• VectorBaseID: AGAMI1_010864
• Length: 687
• Species: Anopheles gambiae
• Alignment Length: 734
• Identity: 220/734 - (29%)
• Similarity: 355/734 - (48%)
• Gaps: 97/734 - (13%)

  Fly    18 CGMANWHPPWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEI 82
            ||......|:.|:.|:.|:::.::||:|.|...:..||..||||:||..:|.|:|.|||.:|:::
Mosquito    37 CGFWVCRGPFWQRLASKKLYVLLFGLMGCILNSTTSYFYGTLTTVEKSIQISSRTVGIITAGSDL 101

  Fly    83 SQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSLLNGTT 147
            |.::.||.|||....|.:|.|||.|||...|||::..||||::....      .|.:.:|.|.|.
Mosquito   102 SFVLASLFLSYYASNRRKPLWIAMGIVSMALSCFVNALPHFLFSKAQ------AELEQNLGNLTK 160

  Fly   148 GSDHSFQNISSVKTERLCGVDKTEDDCD-DLFSYVPLVLIFLSQFVLGVGNTLYYSLGQTYLDDN 211
            |:|:            ||..|:...||. |:....|.:::|...|:.|:|.:||::||.||||||
Mosquito   161 GADN------------LCREDRLAPDCSLDVGDIRPQIVLFFGSFLSGIGTSLYFTLGLTYLDDN 213

  Fly   212 TKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDPTKTPLIDSKDPRWLGAWWLGWVILGTL 276
            .:|...|.:.::|...|.:||:|||....:.|..|:.....|..:..||||:||||:||:.||:.
Mosquito   214 VRKEKVPFLSSLAAFGRRMGPLVGFSLASLCLKYFVHVGVDPGYNQSDPRWIGAWWMGWLALGST 278

  Fly   277 MCLFSGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGA 341
            :.:.:.....|||.||:.                      .|.:|||.:.|..:...|.......
Mosquito   279 LIIIAPFFASFPKVLPRT----------------------AERISLSRQASRASGTSTAEEDVET 321

  Fly   342 NADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIVGP 406
            |..: ...|....:.||:.||..:||.::::||..|...:..|..||:|:|:......|.:|.|.
Mosquito   322 NRKV-SFSDMLVTVRRLVTNKAYVFNNVASIFYFFGYMPYFLFQAKYIEIQYRLTPSQANMITGS 385

  Fly   407 ISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCP--NTFSMTQAGQLN 469
            .|::...:|::.:|||:.|.:.|..::..||||...:|....:.||:..|.  |...:....|
Mosquito   386 TSLVFSALGILIAGMVIQKLRVSSRQLAGWNVITSILSAALIVGYAWFGCSALNNADIVANSQ-- 448

  Fly   470 LTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRGY---NATSKLYEDCSCVVNDPAPKSAA 531
             .::|::.|:||.:.|.|:|.. ...|:.|.||||||..   ...:.||.:|||:.
Mosquito   449 -DASCSLGCNCEFVKYAPICGS-DGQTYLSPCHAGCRDSLKDPTGTTLYTNCSCIA--------- 502

  Fly   532 QRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTKNCNW 596
                     :|..:||                  .:|.....|.|          ||.|..:|..
Mosquito   503 ---------SPTDDLD------------------ANFTSSYGSAT----------PGSCPVDCGT 530

  Fly   597 SFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDS 661
            .|:.|.:...:..:.|.:....|.|:..|.|...||:.:.|.::.:.:|.:.:|.||:||.:||.
Mosquito   531 PFYFFLMCLCLNKFIGGTESAANFLIGLRCVEPRDKAISMGFSMAINTLFSFLPAPIVFGAIIDR 595

  Fly   662 TCLVWTKTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLFDYLVWYYGRNLDIYGDKEAKEEER 726
            ||::|.:||...|||.|||....|.|:|:.:.:...:|..||...|||.:|..|:.||..::...
Mosquito   596 TCVLWGRTCAKQGNCWLYDGEALRASMNYTAAVFVIIGTCFDMGTWYYSKNFKIFDDKPGEQSAS 660

  Fly   727 ANRKDQPITPLLAKKSEQE 745
            .:..::.:..|::|..|:|
Mosquito   661 KSPTERELVSLVSKAKEEE 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_609568.3	OATP	36..684	CDD:460821	197/653 (30%)
LOC1277223	XP_001237849.3	None