DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Oatp33Ea and LOC100536648

DIOPT Version :9

Sequence 1:	NP_001260417.1	Gene:	Oatp33Ea / 34660	FlyBaseID:	FBgn0032433	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	XP_021330963.1	Gene:	LOC100536648 / 100536648	-ID:	-	Length:	416	Species:	Danio rerio

Alignment Length:	442	Identity:	110/442 - (24%)
Similarity:	195/442 - (44%)	Gaps:	73/442 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 MFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRNR 100
            ||:|........::::..|...|:|.:|:||:|||.|.|.|....|:..:::..::||:|.:.:|
Zfish     1 MFIGALAFCYFSKSLTGSYTKSTITQIERRFEIPSSTVGFIDGSFEMGNMLVITLVSYVGAKFHR 65

  Fly   101 PRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSLLNGTTGSDHSFQNISSVKTER-- 163
            |:.|..|::..|:...::..||||.|          .|:.......|....:|..||:..::.
Zfish    66 PKIIGAGVLLMGIGTLLMASPHFIMG----------RYKYGTAATHTNDAGNFTVISTCSSDSQE 120

  Fly   164 -----LCGVDKTEDDCDDLFSYVPLVLIFLSQFVLGVGNTLYYSLGQTYLDDNTKKTNTPLMLAV 223
                 ..|..|.|.:....:     |::.|...:.|:|......||.:::||..:..|:...:..
Zfish   121 TLQQPYSGCQKEEAESSPFW-----VIVLLGNAMRGIGEASIVPLGMSFIDDYARPENSAFYIGC 180

  Fly   224 AMALRMIGPVVGFFFGFISLNTFID--------PTKTPLIDSKDPRWLGAWWLGWVILGTLMCLF 280
            ...:.:|||:|||..|.:..|.::|        .|.||    :|.||:||||||:|:.|.|..|.
Zfish   181 LNTIGVIGPIVGFSLGSLCANLYVDIGLVNQESVTITP----QDSRWVGAWWLGYVVSGLLTLLA 241

  Fly   281 SGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADL 345
            :...|..|:.||:      ||.:. .|....|:.|...::                        :
Zfish   242 AFPFGFLPRALPE------NSQIS-ELDHPSEQHKNPPSI------------------------M 275

  Fly   346 PKLKDFPRALMRLLRNKLLIFNILSAVF----YILGASGFMTFLTKYMEVQFHKDAQSATIIVGP 406
            ..:|||..:..|||.||:.|..:..::.    :.:|    :|:..||:|.||.:.|.....::|.
Zfish   276 EIVKDFAPSFKRLLANKIYILYLAHSIVAFNDFAIG----ITYTPKYLEQQFGQSASKTNFLIGI 336

  Fly   407 ISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCPN 458
            .||....:|:..||:::.:.|..:......|:..|..::...|::..|.|.|
Zfish   337 TSIPTFALGIFLSGLMMKRFKWGLLASARVNLYTGVTTLFLTITFFALSCKN 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_001260417.1	OATP	36..684	CDD:281175	110/442 (25%)
		MFS	40..>280	CDD:119392	67/254 (26%)
		DUF4064	364..447	CDD:290013	18/86 (21%)
		KAZAL_SLC21	470..521	CDD:238650
LOC100536648	XP_021330963.1	OATP	1..>405	CDD:308646	110/442 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010