Protein Alignment Oatp33Ea and slco3a1

DIOPT Version :9

• Sequence 1: NP_001260417.1
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_002933360.2
• Gene: slco3a1 / 100498508
• XenbaseID: XB-GENE-6035424
• Length: 707
• Species: Xenopus tropicalis
• Alignment Length: 712
• Identity: 193/712 - (27%)
• Similarity: 306/712 - (42%)
• Gaps: 139/712 - (19%)

  Fly    29 QKYATTKMFMGVYGLL----------GTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEIS 83
            :|...|..|:.:...|          ||:.|    |.:..|||||:||.:.|...|:|.|..||.
 Frog    25 KKKKKTSCFLNIKIFLVSECALMLAQGTVGA----YLVSMLTTLERRFNLQSADVGVIASSFEIG 85

  Fly    84 QIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQ---DSLLNG 145
            .:.|.|.:||.|.:.:|||.|..|.:...|...:..||.|:          |.:|:   ..:..|
 Frog    86 NLALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFL----------THQYKYEPGEIRWG 140

  Fly   146 TTGSDHSFQNISSVKTERLCGVDKTED----DCDDLFS-----YVPLVLIFLSQFVLGVGNTLYY 201
            ..|.|             :|.::.|..    |.|.:.|     .:..:|:..:|.:||:|.|...
 Frog   141 AEGRD-------------ICSINDTSSGEIPDPDIICSNTATTNMMYLLLIGAQVLLGIGATPVQ 192

  Fly   202 SLGQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDP--TKTPLID--SKDPRW 262
            .||.:|:||:.::.::.|.:.:...:.:.||..||..|......::|.  |.|..:|  ..||||
 Frog   193 PLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAFLTDTSKLDITPDDPRW 257

  Fly   263 LGAWWLGWVILGTLMCLFSGLIGLFPKQL-PKVNASRTNSHLPLALRQTKEELKREENLSLSSRF 326
            :||||.|:::.|.|:...|.|:..||:.| |:::.|..:..  ..|..|:.|..:..|..|  |.
 Frog   258 IGAWWAGFLLCGVLLFFSSLLMFGFPQSLSPRIDRSEESEQ--TMLPDTEYERPKPSNGVL--RH 318

  Fly   327 SSNAALDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEV 391
            ||.....|        :...:|:..|:....||.|.:....:|:|...|...:||..||.||:|.
 Frog   319 SSETEDGT--------SCFQQLRVIPKVTKHLLSNPVFTCIVLAACMEIAVVAGFAAFLGKYLEQ 375

  Fly   392 QFHKDAQSATIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYC 456
            ||:....||..::|..:|....:|:...|:::.|...|....:...::|..:|....:|:.||.|
 Frog   376 QFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGC 440

  Fly   457 ---PNTFSMTQAGQLNLT-------SNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRGYNAT 511
               |........|.:::.       ::||.:|.|:..|:|||| .....|:.|||.|||...|..
 Frog   441 DTGPVAGVTVPYGNISVPGASVERYASCNTDCECQTDSFTPVC-GADGITYLSACFAGCTKMNLA 504

  Fly   512 SKLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRT 576
            .     |||                                   ||.||:
 Frog   505 G-----CSC-----------------------------------LSSVPV--------------- 514

  Fly   577 RRSTSDSVIRPGIC-TKNCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLAL 640
                .::.:.||.| :..|..:|..|.....:.|..|:..:..:|::..|||:.|.||:|.|:..
 Frog   515 ----ENNTVVPGKCPSPGCQEAFLTFLCVMCVCSMIGAMAQTPSVIILIRAVSPELKSYALGVLF 575

  Fly   641 MMISLLALIPGPIIFGRLIDSTCLVWTKTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLF 702
            :::.|:..||.|:|||..||||||.|:..|...|.|.|||...:||.  ::|..:|...|.|
 Frog   576 LLLRLIGFIPPPLIFGAGIDSTCLFWSTFCGTQGACALYDNVAYRYL--YVSIAITLKSLAF 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_001260417.1	OATP	36..684	CDD:281175	185/685 (27%)
		MFS	40..>280	CDD:119392	74/265 (28%)
		DUF4064	364..447	CDD:290013	22/82 (27%)
		KAZAL_SLC21	470..521	CDD:238650	19/57 (33%)
slco3a1	XP_002933360.2	MFS_SLCO3_OATP3	36..560	CDD:340960	156/622 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010