Protein Alignment Oatp33Ea and slco2a1

DIOPT Version :9

• Sequence 1: NP_001260417.1
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_001135668.1
• Gene: slco2a1 / 100216228
• XenbaseID: XB-GENE-5814577
• Length: 637
• Species: Xenopus tropicalis
• Alignment Length: 708
• Identity: 179/708 - (25%)
• Similarity: 305/708 - (43%)
• Gaps: 162/708 - (22%)

  Fly    35 KMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRN 99
            |:|:..:.||...|.:...||...|||:||||.:.|.::|::.|.:|||..:|.:.:||.|.:.:
 Frog    27 KVFVVCHALLQLSQLLYSAYFKSCLTTIEKRFGLSSSSSGLLSSIHEISNAVLIIFVSYFGSRVH 91

  Fly   100 RPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSLLNGTTGSDHSFQNISSVKTERL 164
            |||.|..|.:...|..::|.:|||:          :::||.:.||.        .|.|.|   .|
 Frog    92 RPRVIGVGGLLLALGTFLLTVPHFV----------SEKYQYTELNS--------GNRSQV---LL 135

  Fly   165 CGVDKTEDDCDDLFSYVPL----------VLIFLSQFVLGVGNTLYYSLGQTYLDDNTKKTNTPL 219
            |..:.....|.....::|:          .::.:.|.:.|:|.......|.:|:||..:..|:.|
 Frog   136 CTGENRTFHCKTQGQHLPVTTNNGGSSMWAIMVVGQLLAGIGTVPIQPFGISYVDDFAEPNNSAL 200

  Fly   220 MLAVAMALRMIGPVVGFFFGFISLNTFIDPTKTPL----IDSKDPRWLGAWWLGWVILGTLMCLF 280
            .:|:..|:.:.||..|:..|.:.|..|:|..:..|    :...||||:||||||.:|....:.:.
 Frog   201 YIAILFAVAVFGPAFGYLLGSVVLRMFVDIGRVNLEHVDLTVADPRWIGAWWLGLLIASGCLVIT 265

  Fly   281 SGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADL 345
            |.....||||:               ||  .|:...|||:.        ..:..:.|..|:.:|.
 Frog   266 SIPYFFFPKQM---------------LR--NEKPAPEENVL--------RKIPDVKAEEGSLSDF 305

  Fly   346 PKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIVGPISIM 410
              :|.|||.:.||:.|.|.:..:|....:....:...|||.||:|.|:......|..::|.:::.
 Frog   306 --IKKFPRYVRRLITNPLFLMLVLCQCSFSSVIAALSTFLNKYLEKQYSSSTSYANFLIGAVNLP 368

  Fly   411 GMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCPNTFSMTQAGQL------- 468
            ...:|::..|:::.:...|:..:..:.:.:..:|||..:...|:.|     .|||.::
 Frog   369 TAALGMLIGGIIMKRFCISLQIIPRFALAILLLSILLCVPLFFMGC-----STQALEMGMVEHST 428

  Fly   469 --NLTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRGYNATS----KLYEDCSCVVNDPAP 527
              |..|.|...|:|...::.|||.. ....:.|.||||||.:|.||    ::|.:|||:.:
 Frog   429 SGNTLSTCTSQCACPEYAFQPVCGS-NGVEYLSPCHAGCRAFNQTSSEKLRMYRNCSCITD---- 488

  Fly   528 KSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTK 592
                                                               ::.:...:.|.|..
 Frog   489 ---------------------------------------------------TSGEGTAQTGSCPT 502

  Fly   593 NCNWSFWAFSITSMIVSWFGSSGRVGNVLVN------YRAVAHEDKSFAQGLALMMISLLALIPG 651
            :|:      .:...::.....:|.:..:..|      .|.|..::||||.|:..:::..||.:|.
 Frog   503 SCS------HLLLPVMFLISFAGLIACLTHNPLYMMVLRVVRQDEKSFAIGVQFLLMRFLAWLPA 561

  Fly   652 PIIFGRLIDSTCLVWTKTCNGN-GNCQLY--DQTRFRYSLNFLSCLLTFMGLLFDYLV 706
            |.:||.:||||||||.::|:|| |.|:.|  |..|.||           :||...|.:
 Frog   562 PALFGLVIDSTCLVWDRSCSGNRGACRYYNNDLLRNRY-----------LGLQMGYKI 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_001260417.1	OATP	36..684	CDD:281175	172/683 (25%)
		MFS	40..>280	CDD:119392	73/253 (29%)
		DUF4064	364..447	CDD:290013	15/82 (18%)
		KAZAL_SLC21	470..521	CDD:238650	20/54 (37%)
slco2a1	NP_001135668.1	MFS	25..535	CDD:391944	145/622 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920