Protein Alignment Oatp33Ea and slco2a1

DIOPT Version :10

• Sequence 1: NP_609568.3
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_001428961.1
• Gene: slco2a1 / 100038802
• ZFINID: ZDB-GENE-060606-3
• Length: 625
• Species: Danio rerio
• Alignment Length: 742
• Identity: 184/742 - (24%)
• Similarity: 310/742 - (41%)
• Gaps: 182/742 - (24%)

  Fly     3 EVKRRDPNRPPGHYLCGMANWHPPWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFK 67
            ::..:|..:|.....|.:              |:|:..:|||...|.:...||..|:||:|:|:.
Zfish     2 DIYAKDIKKPKPSLFCNI--------------KIFVLCHGLLQLTQLLYSSYFKSTITTIERRYG 52

  Fly    68 IPSQTTGIILSGNEISQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFI-----YGA 127
            :.|.::|.|.|.:|:...:|...:||:|.:.:|||:|..|.:...:|..||.||||:     |.:
Zfish    53 LDSLSSGTISSLHEVGNTVLIAFVSYLGSRVHRPRFIGLGGLLMSISAMILALPHFLSQPYTYDS 117

  Fly   128 GHEVLQFTKEYQDSLLNGTTGSDHSFQNISSVKTERLCGVDKTEDDCDDLFSYVPL-VLIFLSQF 191
               ||..:::....|....||::             .||    ::|...|...... ||:..:|.
Zfish   118 ---VLHASRQDMCYLRANVTGAE-------------ACG----QEDSRKLMDTSKFWVLMATAQL 162

  Fly   192 VLGVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDPTK----- 251
            :.|:|:......|.:|:||.....|:||.:|:..|:.:.||..|:..|.:.|..::|..|
Zfish   163 LFGIGSVPIQPFGISYIDDFAGAGNSPLYIAILFAVSVFGPSFGYLLGSVVLRIYVDVDKSSAGE 227

  Fly   252 ----TPLIDSKDPRWLGAWWLGWVILGTLMCLFSGLIGLFPKQLPKVNASRTNSHLPLALRQTKE 312
                ||:    ||||:||||:|.:|....:.|.|.....||:.|          |:..:.....|
Zfish   228 ALELTPV----DPRWVGAWWIGLLITSGGLALTSIPYFFFPRSL----------HVEQSFNLEGE 278

  Fly   313 ELKREENLSLSSRFSSNAALDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILG 377
            .:|.:...|.||.                   |...|.||:..:|||.:.|.:..:|....:...
Zfish   279 IMKEDPKKSESSL-------------------LDFFKMFPKIFVRLLLSPLFMLLVLCQCCFSSV 324

  Fly   378 ASGFMTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGG 442
            .:|..|||.|::|.|:...|..:::::|.:::..:.:|::..|:::.:...|...:..::|::..
Zfish   325 IAGLATFLNKFLERQYSASAAYSSLLIGALNLPSIAIGMVLGGLIMKRWGLSFRAIPRFSVVMLT 389

  Fly   443 ISILGQISYAFLYCPNTFSMTQ--AGQLNLTSN--------CNMNCSCEGISYTPVCHEPTDTTF 497
            ||:...:...|:.||     ||  ||...:.||        |:.||||...::.|||.|..:..:
Zfish   390 ISVFCCVPLFFMGCP-----TQDVAGVYPIKSNSTNGIHLTCSANCSCPISTFNPVCGEGNNIEY 449

  Fly   498 FSACHAGCRGYNATSK------LYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYL 556
            .|.|||||..|....|      .|.:|.|:                  ||
Zfish   450 ISPCHAGCANYTTDPKNPYRVQSYINCKCI------------------PT--------------- 481

  Fly   557 SGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTKNCNWSFWAFSITSMIVSWFGSSGRVGNVL 621
                                      ...:||.|:..|.    .:.:..|::  ...:|.:.::.
Zfish   482 --------------------------GTAKPGPCSNTCP----HYLLPVMLL--ISLAGLIASLT 514

  Fly   622 VN------YRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVWTKTCNGNGNCQLYD 680
            .|      .|||..|:||||.|:..:::.:|..:|.|.:||..|||||:.|...|.....|..||
Zfish   515 HNPIYMMVLRAVPPEEKSFAIGIQFLLLRVLTWLPAPALFGMTIDSTCIWWKTACEKKQGCGYYD 579

  Fly   681 QT--RFRY---SLNFLS---CLLTFMG 699
            ..  |.||   .:.:.:   .||.|:|
Zfish   580 NNLLRNRYLGLQVGYKTLGIALLAFIG 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp33Ea	NP_609568.3	OATP	36..684	CDD:460821	173/686 (25%)
slco2a1	NP_001428961.1	None