Protein Alignment eRF3 and Hbs1l

DIOPT Version :9

• Sequence 1: NP_001260415.1
• Gene: eRF3 / 34658
• FlyBaseID: FBgn0020443
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_006512866.1
• Gene: Hbs1l / 56422
• MGIID: 1891704
• Length: 685
• Species: Mus musculus
• Alignment Length: 590
• Identity: 195/590 - (33%)
• Similarity: 305/590 - (51%)
• Gaps: 54/590 - (9%)

  Fly    31 SVVNVAEEAAAVVVAAAAAEETADPGPASGSATPATTPDSVGSGGSTAGAAPPPPTAQGAGAAAP 95
            ||::.:.::.:.:|...|....:......|...|..|.:   ..|.:..|....|.......|:|
Mouse   142 SVISRSSQSESEIVPKVAKMTVSGKKQTMGFEVPGLTSE---ENGLSVRAPHKGPPGDDVSVASP 203

  Fly    96 SAQPPTSSSNSASPAPGSPATTPSAGAAAADPTPIDGLNPSDKIANNETDPADSWDVDDAVITPE 160
            :. |.|.:..||.|.| |..|:...|:.   |||:.
Mouse   204 NI-PETGTPKSALPPP-SLQTSEELGST---PTPVR----------------------------- 234

  Fly   161 DEEVEDAEFTEGEATPKVSKKKVVKVEENRSKREHVNVVFIGHVDAGKSTIGGQIMSLTGMVDKR 225
                     ..|:...::..|  .::|:.:..::.:|:|.||||||||||:.|.::.|.|.|:||
Mouse   235 ---------KSGKLRQQIDVK--AELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNVNKR 288

  Fly   226 TLEKYEREAREKSRESWYLSWALDTNQEERDKGKTVEVGRAFFETDRKHFTILDAPGHKSFVPNM 290
            |:.|||:|:::..:.|:..:|.||...|||::|.|::||...|||..|..|::||||||.|:|||
Mouse   289 TMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNM 353

  Fly   291 IGGAAQADLAVLVISARKGEFETGFDRGGQTREHAMLAKTAGVKHLVVLVNKMDDPTVNWDQTRY 355
            |.||||||:||||:.|.:||||.||:.|||||||.:|.::.||..|.|.|||||.  |||.|.|:
Mouse   354 ITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQ--VNWQQERF 416

  Fly   356 NECKDKILPYLKKLGFNPAKDLTFMPCSGLSGYGLKDQIPET-LCPWYRGPAFIPFIDELPSLNR 419
            .|...|:..:||:.||..: |:.|:|.|||||..|..:...: |..||:|...:..||......|
Mouse   417 QEITGKLGHFLKQAGFKES-DVAFIPTSGLSGENLTARSQSSDLTTWYKGMCLLEQIDSFKPPQR 480

  Fly   420 KSDGPFIMPIVDKYKDMGT--VVMGKVESGTARKGQNLLVMPNRTQVAVDQLFSDDFEVTSVGPG 482
            ..|.||.:.:.|.:||.|:  .|.||:|:|..:.|..||.||.........:...|..|.....|
Mouse   481 SIDKPFRLCVSDVFKDQGSGFCVTGKIEAGYIQTGDRLLAMPPNETCTAKGITLHDEPVDWAAAG 545

  Fly   483 ENVKIKLKGIEEEDVSPGFVLCDAANPIKTGKIFDAQVVILEHKSIICAGYSAVMHIHCAAEEVT 547
            ::|.:.|.|::...::.|.:.|....|||....|.|::::...:..|..|:..::|....:|...
Mouse   546 DHVNLTLVGMDIIKINVGCIFCGPKEPIKACTRFRARILVFNIEVPITKGFPVLLHYQTVSEPAV 610

  Fly   548 VKALICLVDKKSGDKSKTRPRFVKQDQVAIMRIECSGMICLEQFKLFPQMGRFTLRDENKTIAIG 612
            :|.||.:::|.:|:.:|.:|:.:.:.|.|::.::....:.||.:|.|.::|||.||....|:|.|
Mouse   611 IKRLISVLNKSTGEVTKKKPKLLTKGQNALVELQTQRPVALELYKDFKELGRFMLRYGGSTVAAG 675

  Fly   613 KVLKV 617
            .|.:|
Mouse   676 VVTEV 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eRF3	NP_001260415.1	PAM2	12..28	CDD:284542
		TEF1	191..619	CDD:227581	168/430 (39%)
		EF1_alpha	197..416	CDD:206670	110/219 (50%)
		eRF3_II	424..505	CDD:293906	23/82 (28%)
		eRF3_C_III	511..617	CDD:294003	29/105 (28%)
Hbs1l	XP_006512866.1	HBS1_N	46..113	CDD:370196
		TEF1	254..680	CDD:227581	167/428 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5256
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1150082at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820