Protein Alignment eRF3 and CG2017

DIOPT Version :9

• Sequence 1: NP_001260415.1
• Gene: eRF3 / 34658
• FlyBaseID: FBgn0020443
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_649603.3
• Gene: CG2017 / 40733
• FlyBaseID: FBgn0037391
• Length: 643
• Species: Drosophila melanogaster
• Alignment Length: 512
• Identity: 103/512 - (20%)
• Similarity: 181/512 - (35%)
• Gaps: 148/512 - (28%)

  Fly   178 VSKKKVVKVEENRSKREHVNVVFIGHVDAGKSTIGGQIMSLTGMVDKRTLEKYEREAREKSRESW 242
            |::..|.|:.:::...| |.|..:|..||||||       |.|::.:..|:.....||..
  Fly   199 VAEVLVRKIPDDQHNIE-VRVAVLGGADAGKST-------LLGVLTQDELDNGHGRARLN----- 250

  Fly   243 YLSWALDTNQEERDKGKTV---------------------EVGRAFFETDR--KHFTILDAPGHK 284
                 :..:..|...|:|.                     |:..|...:||  |..|.:|..||:
  Fly   251 -----MFRHMHEIQSGRTSCISHETLGFDALGNVVNYKYNEMMTAEEISDRSSKLVTFMDLAGHR 310

  Fly   285 SFVPNMIGGAA--QADLAVLVISARKGEFETGFDRGGQTREHAMLAKTAGVKHLVVLVNKMD--- 344
            .::...:...:  ....|:||:||..|..:|       |.||..:.:...:. ..|||.|.|
  Fly   311 RYMRTTVQALSGYSPHYAMLVVSAGSGCNDT-------TEEHLAIVRALDMP-FFVLVTKTDITS 367

  Fly   345 -DPTV--------------------NWDQ---TRYNECKDKILPY-----LKKLGFNPAKDLTFM 380
             |.||                    |.|:   ...|:..:.|:|.     :...|.|......::
  Fly   368 PDATVQELCNLLTTIGCRKVPFVVTNTDEAISAGSNQISENIVPIFCVSNVTGTGLNLVTKFLYV 432

  Fly   381 PCSGLSGYGLKDQIPETLCPWYRGPAFIPFIDELPSLNRKSDGPFIMPIVDKYKDMGTVVMGKVE 445
            ...|:|. ..||::.:..|.:.        :||                :.:..|:|.||.|.:.
  Fly   433 LSPGISN-AEKDRLEQESCEFQ--------VDE----------------IFRVSDVGPVVGGLLV 472

  Fly   446 SGTARKGQNLLVMP----NRTQVAVDQLFSDDFEVTSVGPGENVKIKLKGIEEEDV---SPGFVL 503
            .|...:...:.:.|    :...|.|:.:..:......|..|::..:...  .::||   ..|.||
  Fly   473 QGVLTENMAMKIGPLPDGSFHPVTVNTIHRNKAPCRVVRAGQSASLSFS--MDQDVPTLRSGMVL 535

  Fly   504 C-DAAN----PIKTGKIFDAQVVILEHKSIICAGYSAVMHIHCAAEEVTVKALICLVDKKSGDKS 563
            . |..|    |..| ..|.|:|.:|.|.:.|..|:...:||....:...::.::      .|::.
  Fly   536 LGDIGNSLDEPYGT-FFFQAKVSVLFHATAIYVGFQTTVHIGSIRQTAVIRGIM------GGERL 593

  Fly   564 KTRPRFVKQDQVAIMRIECSGMICLEQFKLFPQMGRFTLR---DENKTIAIGKVLKV 617
            .|.              :|:.:  :.:|...|:..|..:|   .|..:..||.|.:|
  Fly   594 GTN--------------DCASV--MFEFVGHPEYVRPGMRILFREGTSKGIGVVTQV 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eRF3	NP_001260415.1	PAM2	12..28	CDD:284542
		TEF1	191..619	CDD:227581	100/499 (20%)
		EF1_alpha	197..416	CDD:206670	57/275 (21%)
		eRF3_II	424..505	CDD:293906	16/88 (18%)
		eRF3_C_III	511..617	CDD:294003	21/108 (19%)
CG2017	NP_649603.3	GTPBP1	100..635	CDD:227583	103/512 (20%)
		GTPBP1_like	217..436	CDD:206728	50/243 (21%)
		GTPBP_II	450..536	CDD:293895	18/111 (16%)
		GTPBP_III	547..634	CDD:294007	21/109 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464646
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930