DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment eRF3 and eef1a1o

DIOPT Version :10

Sequence 1:NP_477259.1 Gene:eRF3 / 34658 FlyBaseID:FBgn0020443 Length:619 Species:Drosophila melanogaster
Sequence 2:NP_989301.1 Gene:eef1a1o / 394920 XenbaseID:XB-GENE-1218983 Length:461 Species:Xenopus tropicalis


Alignment Length:446 Identity:168/446 - (37%)
Similarity:258/446 - (57%) Gaps:31/446 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly   195 HVNVVFIGHVDAGKSTIGGQIMSLTGMVDKRTLEKYEREAREKSRESWYLSWALDTNQEERDKGK 259
            |:|:|.|||||:||||..|.::...|.:||||:||:|:||.|..:.|:..:|.||..:.||::|.
 Frog     7 HINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGI 71

  Fly   260 TVEVGRAFFETDRKHFTILDAPGHKSFVPNMIGGAAQADLAVLVISARKGEFETGFDRGGQTREH 324
            |:::....|||.:.:.||:|||||:.|:.|||.|.:|||.|||:::...||||.|..:.||||||
 Frog    72 TIDISLWKFETGKFYITIIDAPGHRDFIKNMITGTSQADCAVLIVAGGVGEFEAGISKNGQTREH 136

  Fly   325 AMLAKTAGVKHLVVLVNKMDDPTVNWDQTRYNECKDKILPYLKKLGFNPAKDLTFMPCSGLSGYG 389
            |:||.|.|||.|::.|||||.....:.|.|:.|...::..|:||:|:||| .:.|:|.||..|..
 Frog   137 ALLAFTLGVKQLIIGVNKMDSTEPPFSQKRFEEITKEVSAYIKKIGYNPA-TVPFVPISGWHGDN 200

  Fly   390 LKDQIPETLCPWYRG---------PAFIPFIDELPSL---NRKSDGPFIMPIVDKYK--DMGTVV 440
            :.:  ..|..||::|         .:.:..::.|..:   .|.:|.|..:|:.|.||  .:|||.
 Frog   201 MLE--ASTNMPWFKGWKIERKEGNASGVTLLEALDCIIPPQRPTDKPLRLPLQDVYKIGGIGTVP 263

  Fly   441 MGKVESGTARKGQNLLVMPNRTQVAVDQLFSDDFEVTSVGPGENVKIKLKGIEEEDVSPGFVLCD 505
            :|:||:|..:.|..:...|:.....|..:......:....||:||...:|.|..:|:..|.|..|
 Frog   264 VGRVETGVLKPGMVVTFAPSNVTTEVKSVEMHHEALQEALPGDNVGFNVKNISVKDIRRGNVAGD 328

  Fly   506 AAN--PIKTGKIFDAQVVILEHKSIICAGYSAVM-----HIHCAAEEVTVKALICLVDKKSGDKS 563
            :.|  |::.| .|.|||:||.|...|.|||:.|:     ||.|...|:..|     :|::||.|.
 Frog   329 SKNDPPMQAG-TFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKQK-----IDRRSGKKL 387

  Fly   564 KTRPRFVKQDQVAIMRIECSGMICLEQFKLFPQMGRFTLRDENKTIAIGKVLKVVE 619
            :..|:|:|....||:.:.....:|:|.|..:|.:|||.:||..:|:|:| |:|.|:
 Frog   388 EDDPKFLKSGDAAIVEMIPGKPMCVETFSDYPPLGRFAVRDMRQTVAVG-VIKGVD 442

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
eRF3NP_477259.1 PAM2 12..28 CDD:429316
EF1_alpha 197..416 CDD:206670 96/227 (42%)
eRF3_II 424..505 CDD:293906 24/82 (29%)
eRF3_C_III 511..617 CDD:294003 40/110 (36%)
eef1a1oNP_989301.1 PTZ00141 1..461 CDD:185474 168/446 (38%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.