Protein Alignment eRF3 and Dgp-1

DIOPT Version :10

• Sequence 1: NP_477259.1
• Gene: eRF3 / 34658
• FlyBaseID: FBgn0020443
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_611302.1
• Gene: Dgp-1 / 37080
• FlyBaseID: FBgn0027836
• Length: 669
• Species: Drosophila melanogaster
• Alignment Length: 643
• Identity: 132/643 - (20%)
• Similarity: 220/643 - (34%)
• Gaps: 222/643 - (34%)

  Fly   105 NSASPAPGSPATTPSAGAAAADPTPIDGL---------------------NPS------------ 136
            |:...||...|......:|.::...:|||                     .|:
  Fly     2 NNIQSAPNGVAVGVGIKSARSNIFNVDGLPQQMAAMSVDYSSIRGKDVLVQPTEEQIELLQKRLQ 66

  Fly   137 DKIANN--ET--DPADSWDVDDAVITPEDEEVE-----------DAEFTEGEATPKVSKKKVVKV 186
            |:||:|  ||  :.....|..|:.:.||..|..           ||:              |||:
  Fly    67 DRIADNCGETIYEIGVGEDGSDSGLNPEQFEASVATLHLLAANIDAD--------------VVKL 117

  Fly   187 EENRSK---------REHVN--------VVFIGHVDAGKSTIGGQIMSLTGMVDKRTLEKYEREA 234
            .|.|::         |:|::        |..:|:|||||||       |.|::....|:.....|
  Fly   118 RERRAEKGQSAQFLIRKHIDTTDFMEIRVAVVGNVDAGKST-------LLGVLTHGELDNGRGHA 175

  Fly   235 REKSRESWYLSWALDTNQEERDKGKTVEVGRAFF-----------------------ETDRKHFT 276
            |::          |..::.|.:.|:|..||....                       |...|..|
  Fly   176 RQR----------LFRHKHEIESGRTSSVGNDILGFDGVGNVVNKPDHGHLDWVKICENSAKVIT 230

  Fly   277 ILDAPGHKSFVPNMIGGAA--QADLAVLVISARKGEFETGFDRGGQTREHAMLAKTAGVKHLVVL 339
            .:|..||:.::...:.|..  ..|..:|:|.|..|..       |.|:||..||....|...||:
  Fly   231 FIDLAGHERYLKTTVFGMTGHAPDFGMLMIGANAGII-------GMTKEHLGLALALAVPVFVVV 288

  Fly   340 VNKMDDPTVNWDQTRYNECKDKILPYLKKLGFNPAK---------------DLTFMPCSGLSGYG 389
                         |:.:.|...:|....||.|...|               |:.....:.:|
  Fly   289 -------------TKIDMCPANVLQENMKLLFKMLKSQGCRKVPVVVRSHDDVVLSATNFVS--- 337

  Fly   390 LKDQIPETLCPWYR-----GPAF-------------IPFIDELPSLNRKSDGPFIMPIVDKYKDM 436
                  |.|||.::     |...             :|..:.||: ..:.|..:.:|      .:
  Fly   338 ------ERLCPIFQVSNVTGDNLELLKMFLNLLSTRMPGSESLPA-EFQIDDVYAVP------GV 389

  Fly   437 GTVVMGKVESGTARKGQNLLVMPNR----TQVAVDQLFSDDFEVTSVGPGENVKIKLKGIEEEDV 497
            ||||.|....||.|....|::.|:.    ..:.:..:......|..|..|:.....||.|:...:
  Fly   390 GTVVSGTCLQGTIRLNDCLMLGPDAVGSFVPITIKSIHRKRMNVARVRCGQTASFALKKIKRAYL 454

  Fly   498 SPGFVLCDAANPIKTGKIFDAQVVILEHKSIICAGYSAVMHIHCAAEEVTVKAL----ICLVDKK 558
            ..|.|:.......:....|:.::::|.|.:.|.|.|.|:  :||.:...|...:    .||   :
  Fly   455 RKGMVMVSQDLKPQACWEFEGEILVLHHPTTISARYQAM--VHCGSIRQTASIIHMSRDCL---R 514

  Fly   559 SGDKSKTRPRFVKQDQVAIMRIECSGMICLEQFKLFPQMGRFTLRDENKTIAIGKVLK 616
            :|||:..:.||:||.:                   :.:.|:..:..|.:|.|:|.:|:
  Fly   515 TGDKAHVKFRFIKQPE-------------------YIRAGQRLVFREGRTKAVGNILR 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eRF3	NP_477259.1	PAM2	12..28	CDD:429316
		EF1_alpha	197..416	CDD:206670	57/284 (20%)
		eRF3_II	424..505	CDD:293906	19/84 (23%)
		eRF3_C_III	511..617	CDD:294003	25/110 (23%)
Dgp-1	NP_611302.1	GTPBP1	55..556	CDD:444076	123/590 (21%)
		dermokine	<561..>651	CDD:455732