Protein Alignment eRF3 and gspt1l

DIOPT Version :9

• Sequence 1: NP_001260415.1
• Gene: eRF3 / 34658
• FlyBaseID: FBgn0020443
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_942101.1
• Gene: gspt1l / 325284
• ZFINID: ZDB-GENE-030131-4009
• Length: 577
• Species: Danio rerio
• Alignment Length: 620
• Identity: 366/620 - (59%)
• Similarity: 434/620 - (70%)
• Gaps: 69/620 - (11%)

  Fly     3 AQENTEISTKFSTLNVNAVEFVPSFSYNSVVNVAEEAAAVVVAA----AAAEETADPGPASGSAT 63
            ||.:.::|...::|||:|..|||:..           |||.|.:    .:||.....||.:.:..
Zfish    19 AQVDVQLSKALTSLNVDAKPFVPNVH-----------AAVFVPSFQQKGSAETVESAGPDTDANV 72

  Fly    64 PATTPDSVGSGGSTAGAAPPPPTAQGAGAAAPSAQPPTSSSNSASPAPGSPATTPSAGAAAADPT 128
            ....|:           |||........|...:.:...|..:.|...||.||.
Zfish    73 EVAEPE-----------APPMENGDAEMATDDTWEQKGSEPSEAEAEPGGPAR------------ 114

  Fly   129 PIDGLNPSDKIANNETDPADSWDVDDAVITPEDEEVEDAEFTEGEATPKVSKKKVVKVEENRSKR 193
              ||..|.:          ||         |::|.:|:.|        :|...|||..:.|..|:
Zfish   115 --DGGQPEE----------DS---------PQEEGMEEEE--------EVPTPKVVPTQPNAPKK 150

  Fly   194 EHVNVVFIGHVDAGKSTIGGQIMSLTGMVDKRTLEKYEREAREKSRESWYLSWALDTNQEERDKG 258
            |||||||||||||||||||||||.|||||||||||||||||:||:||:|||||||||||||||||
Zfish   151 EHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKG 215

  Fly   259 KTVEVGRAFFETDRKHFTILDAPGHKSFVPNMIGGAAQADLAVLVISARKGEFETGFDRGGQTRE 323
            ||||||||:|||::||||||||||||||||||||||:||||||||||||||||||||::||||||
Zfish   216 KTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTRE 280

  Fly   324 HAMLAKTAGVKHLVVLVNKMDDPTVNWDQTRYNECKDKILPYLKKLGFNPAKDLTFMPCSGLSGY 388
            |||||||||||||:|||||||||||||...||.|||:|::|:|||:||||.||:.|||||||:|.
Zfish   281 HAMLAKTAGVKHLIVLVNKMDDPTVNWSLERYEECKEKLVPFLKKVGFNPRKDVHFMPCSGLNGA 345

  Fly   389 GLKDQIPETLCPWYRGPAFIPFIDELPSLNRKSDGPFIMPIVDKYKDMGTVVMGKVESGTARKGQ 453
            .||:  |...||||.|..|||.:|.||:.||.||||..:||||||||||||::||:|||:..|.|
Zfish   346 NLKE--PAENCPWYTGLPFIPHLDSLPNFNRSSDGPVRLPIVDKYKDMGTVILGKLESGSIGKAQ 408

  Fly   454 NLLVMPNRTQVAVDQLFSDDFEVTSVGPGENVKIKLKGIEEEDVSPGFVLCDAANPIKTGKIFDA 518
            .|::||||..|.|..|.||:.|....|||||:|::|||||||::.|||:||:|.|...||:.|||
Zfish   409 QLVMMPNRHTVEVLSLLSDEVETDEAGPGENLKLRLKGIEEEEILPGFILCNAENLCHTGRTFDA 473

  Fly   519 QVVILEHKSIICAGYSAVMHIHCAAEEVTVKALICLVDKKSGDKSKTRPRFVKQDQVAIMRIECS 583
            |:||:|||||||.||:||:|||...|||.:.|||||||||:||||||||||||||||.|.|:..:
Zfish   474 QIVIIEHKSIICPGYNAVLHIHTCIEEVQITALICLVDKKTGDKSKTRPRFVKQDQVCIARLRTA 538

  Fly   584 GMICLEQFKLFPQMGRFTLRDENKTIAIGKVLKVV 618
            |.||||.||.||||||||||||.||||||||||:|
Zfish   539 GTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLV 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eRF3	NP_001260415.1	PAM2	12..28	CDD:284542	7/15 (47%)
		TEF1	191..619	CDD:227581	323/428 (75%)
		EF1_alpha	197..416	CDD:206670	180/218 (83%)
		eRF3_II	424..505	CDD:293906	48/80 (60%)
		eRF3_C_III	511..617	CDD:294003	80/105 (76%)
gspt1l	NP_942101.1	TEF1	150..572	CDD:227581	320/423 (76%)
		EF1_alpha	154..370	CDD:206670	179/217 (82%)
		eRF3_II	379..460	CDD:293906	48/80 (60%)
		eRF3_C_III	466..572	CDD:294003	80/105 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	364	1.000	Domainoid score	I890
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68226
Inparanoid	1	1.050	692	1.000	Inparanoid score	I665
OMA	1	1.010	-	-		QHG54149
OrthoDB	1	1.010	-	-		D1150082at2759
OrthoFinder	1	1.000	-	-		FOG0002347
OrthoInspector	1	1.000	-	-		otm26021
orthoMCL	1	0.900	-	-		OOG6_101550
Panther	1	1.100	-	-	LDO	PTHR23115
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2104
SonicParanoid	1	1.000	-	-		X149
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	14.010