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Protein Alignment eRF3 and Hbs1l

DIOPT Version :9

Sequence 1:	NP_001260415.1	Gene:	eRF3 / 34658	FlyBaseID:	FBgn0020443	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	XP_038962831.1	Gene:	Hbs1l / 293408	RGDID:	1308509	Length:	682	Species:	Rattus norvegicus

Alignment Length:	622	Identity:	205/622 - (32%)
Similarity:	308/622 - (49%)	Gaps:	74/622 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 FSYNSVVNVAEEAAAVVVAAAAAEETADPG-PASGSA------------TPATTPDSVGSGGSTA 78
            |.....::|..|...|......:|.....| |:.|.:            .|.....:|.....|.
  Rat   106 FDVQKALSVVLEQDGVQTLKEKSERAVCAGQPSKGKSVISRSSQSESEIVPKVAKMTVSGKKQTM 170

  Fly    79 GAAPP--PPTAQGAGAAAPSAQPPTSSSNSASP------APGSPATTPSAGAA---AADPTPIDG 132
            |...|  |....|....||...||....:.|||      .|.|.|..||...:   ...|||
  Rat   171 GFEVPGLPSEENGHNVRAPYKGPPGDDVSIASPNVPETGTPKSTAHPPSLQTSEELGCTPTP--- 232

  Fly   133 LNPSDKIANNETDPADSWDVDDAVITPEDEEVEDAEFTEGEATPKVSKKKVVK--VEENRSKREH 195
            |..|.|:.                     ::::                  ||  :|:.:..::.
  Rat   233 LRKSGKLR---------------------QQID------------------VKAGLEKRQGGKQL 258

  Fly   196 VNVVFIGHVDAGKSTIGGQIMSLTGMVDKRTLEKYEREAREKSRESWYLSWALDTNQEERDKGKT 260
            :|:|.||||||||||:.|.::.|.|.|:|||:.|||:|:::..:.|:..:|.||...|||::|.|
  Rat   259 LNLVVIGHVDAGKSTLMGHMLYLLGNVNKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVT 323

  Fly   261 VEVGRAFFETDRKHFTILDAPGHKSFVPNMIGGAAQADLAVLVISARKGEFETGFDRGGQTREHA 325
            ::||...|||..|..|::||||||.|:||||.||||||:||||:.|.:||||.||:.|||||||.
  Rat   324 MDVGMTKFETTTKVVTLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHG 388

  Fly   326 MLAKTAGVKHLVVLVNKMDDPTVNWDQTRYNECKDKILPYLKKLGFNPAKDLTFMPCSGLSGYGL 390
            :|.::.||..|.|.|||||.  |||.|.|:.|...|:..:||:.||..: |:.|:|.|||||..|
  Rat   389 LLVRSLGVTQLAVAVNKMDQ--VNWQQERFQEITGKLGHFLKQAGFKES-DVAFIPTSGLSGENL 450

  Fly   391 KDQIPET-LCPWYRGPAFIPFIDELPSLNRKSDGPFIMPIVDKYKDMGT--VVMGKVESGTARKG 452
            ..:...: |..||:|...:..||......|..|.||.:.:.|.:||.|:  .|.||:|:|..:.|
  Rat   451 TSRSQSSDLTKWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCVTGKIEAGYVQTG 515

  Fly   453 QNLLVMPNRTQVAVDQLFSDDFEVTSVGPGENVKIKLKGIEEEDVSPGFVLCDAANPIKTGKIFD 517
            ..||.||.........:...|..|.....|::|.:.|.|::...::.|.:.|....|||....|.
  Rat   516 DRLLAMPPNETCTAKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKEPIKACTRFR 580

  Fly   518 AQVVILEHKSIICAGYSAVMHIHCAAEEVTVKALICLVDKKSGDKSKTRPRFVKQDQVAIMRIEC 582
            |:::|...:..|..|:..::|....:|...:|.||.:::|.:|:.:|.:|:.:.:.|.|::.::.
  Rat   581 ARILIFNIEVPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKLLTKGQNALVELQT 645

  Fly   583 SGMICLEQFKLFPQMGRFTLRDENKTIAIGKVLKVVE 619
            ...:.||.:|.|.::|||.||....|:|.|.|.::.|
  Rat   646 QRPVALELYKDFKELGRFMLRYGGSTVAAGVVTEIKE 682

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.