Protein Alignment eRF3 and eRF3

DIOPT Version :10

• Sequence 1: NP_477259.1
• Gene: eRF3 / 34658
• FlyBaseID: FBgn0020443
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_061517594.1
• Gene: eRF3 / 1280274
• VectorBaseID: AGAMI1_011461
• Length: 607
• Species: Anopheles gambiae
• Alignment Length: 620
• Identity: 472/620 - (76%)
• Similarity: 522/620 - (84%)
• Gaps: 23/620 - (3%)

  Fly     5 ENTEISTKFSTLNVNAVEFVPSFSYNSVVNVAEEAAAVVVAAAAAEETADP-GPASGSATPATTP 68
            ::.|::.|.|||||||:||||. .::......:.|||...|.:.......| .||:.:|.|||..
Mosquito     6 DSNEVAKKLSTLNVNAMEFVPG-KFSPAPAAVQTAAAATAAPSGTSPAGSPTAPAAATALPATAS 69

  Fly    69 DSVGSGGSTAGAAPPPPTAQGAGAAAPSAQPPTSSSNSASPAPGSPATTPSAGAAAADPTPID-G 132
            .:..|.||::|..    ...|.|.....|..|||:  :|:|.|      ||:.|    |||:: .
Mosquito    70 SATSSAGSSSGGG----GGGGGGGGGGGATTPTST--AATPTP------PSSSA----PTPMERD 118

  Fly   133 LNPSDKIANNETDPADSWDV-DDAVITPEDEEVE--DAEFTEGEATPKVSKKKVVKVEENRSKRE 194
            .:|.....|||::|.||||. :|:::||||||:|  |.| .:||..|||||||..||||:|||:|
Mosquito   119 ADPVQMPENNESEPLDSWDAEEDSILTPEDEEMELDDVE-ADGETAPKVSKKKPPKVEESRSKKE 182

  Fly   195 HVNVVFIGHVDAGKSTIGGQIMSLTGMVDKRTLEKYEREAREKSRESWYLSWALDTNQEERDKGK 259
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   183 HVNVVFIGHVDAGKSTIGGQIMSLTGMVDKRTLEKYEREAREKSRESWYLSWALDTNQEERDKGK 247

  Fly   260 TVEVGRAFFETDRKHFTILDAPGHKSFVPNMIGGAAQADLAVLVISARKGEFETGFDRGGQTREH 324
            |||||||:|||::||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   248 TVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGAAQADLAVLVISARKGEFETGFDRGGQTREH 312

  Fly   325 AMLAKTAGVKHLVVLVNKMDDPTVNWDQTRYNECKDKILPYLKKLGFNPAKDLTFMPCSGLSGYG 389
            |||||||||||||||||||||||||||..||||||||||||||||||||.|||||||.||::|.|
Mosquito   313 AMLAKTAGVKHLVVLVNKMDDPTVNWDLERYNECKDKILPYLKKLGFNPLKDLTFMPVSGITGQG 377

  Fly   390 LKDQIPETLCPWYRGPAFIPFIDELPSLNRKSDGPFIMPIVDKYKDMGTVVMGKVESGTARKGQN 454
            |::.|..:.||||:|||||||||||||||||:||||||||||||||||||:|||||||.|:||.|
Mosquito   378 LREPIDASTCPWYQGPAFIPFIDELPSLNRKTDGPFIMPIVDKYKDMGTVLMGKVESGVAKKGTN 442

  Fly   455 LLVMPNRTQVAVDQLFSDDFEVTSVGPGENVKIKLKGIEEEDVSPGFVLCDAANPIKTGKIFDAQ 519
            ||||||||||.||||:|||.||||||||||||||:|||||||||||||||||:||||||||||||
Mosquito   443 LLVMPNRTQVCVDQLWSDDEEVTSVGPGENVKIKVKGIEEEDVSPGFVLCDASNPIKTGKIFDAQ 507

  Fly   520 VVILEHKSIICAGYSAVMHIHCAAEEVTVKALICLVDKKSGDKSKTRPRFVKQDQVAIMRIECSG 584
            ||||||||||||||||||||||||||:||||||||||||:|:|||||||||||||||||||||||
Mosquito   508 VVILEHKSIICAGYSAVMHIHCAAEEITVKALICLVDKKTGEKSKTRPRFVKQDQVAIMRIECSG 572

  Fly   585 MICLEQFKLFPQMGRFTLRDENKTIAIGKVLKVVE 619
            :||||||||||||||||||||||||||||||||||
Mosquito   573 LICLEQFKLFPQMGRFTLRDENKTIAIGKVLKVVE 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eRF3	NP_477259.1	PAM2	12..28	CDD:429316	12/15 (80%)
		EF1_alpha	197..416	CDD:206670	200/218 (92%)
		eRF3_II	424..505	CDD:293906	72/80 (90%)
		eRF3_C_III	511..617	CDD:294003	101/105 (96%)
eRF3	XP_061517594.1	None